Zobrazeno 1 - 10
of 15
pro vyhledávání: '"James M. Clegg"'
Autor:
Yifei Yang, Sam A. Booker, James M. Clegg, Idoia Quintana-Urzainqui, Anna Sumera, Zrinko Kozic, Owen Dando, Sandra Martin Lorenzo, Yann Herault, Peter C. Kind, David J. Price, Thomas Pratt
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background Autism spectrum condition or ‘autism’ is associated with numerous genetic risk factors including the polygenic 16p11.2 microdeletion. The balance between excitatory and inhibitory neurons in the cerebral cortex is hypothesised
Externí odkaz:
https://doaj.org/article/94e25852ab114ae8b3fe8bb4a3c913b2
Autor:
Wai Kit Chan, Katherine Howe, James M Clegg, Scott E Guimond, David J Price, Jeremy E Turnbull, Thomas Pratt
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130147 (2015)
Heparan sulfate (HS) is a linear carbohydrate composed of polymerized uronate-glucosamine disaccharide units that decorates cell surface and secreted glycoproteins in the extracellular matrix. In mammals HS is subjected to differential sulfation by f
Externí odkaz:
https://doaj.org/article/9e8e9c1017294f75b55be1fe7b23f2a7
Publikováno v:
Journal of Cystic Fibrosis. 21:549-550
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3679e3c4c9345cd947370679e6f07236
https://doi.org/10.1016/j.jcf.2021.07.021
https://doi.org/10.1016/j.jcf.2021.07.021
Autor:
Price Dj, Yifei Yang, Martin Lorenzo S, Sam A. Booker, Owen Dando, Peter C. Kind, Yann Herault, Thomas Pratt, Idoia Quintana-Urzainqui, Zrinko Kozic, Anna Sumera, James M. Clegg
Autism spectrum condition or ‘autism’ is associated with numerous monogenic and polygenic genetic risk factors including the polygenic 16p11.2 microdeletion. A central question is what neural cells are affected. To systematically investigate we a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1013a8f8ed9caab96356c390f1766776
https://doi.org/10.1101/2021.06.03.446920
https://doi.org/10.1101/2021.06.03.446920
Publikováno v:
The AAO Journal. 29:7-11
Context The use of osteopathic manipulative medicine (OMM) continues to decline in medical practice, despite an increasing number of osteopathic physicians. Objective This pilot study was designed to determine if a brochure created to increase knowle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f742f3514dd3b9613edf451169662d
https://doi.org/10.53702/2375-5717-29.3.7
https://doi.org/10.53702/2375-5717-29.3.7
Autor:
James M. Clegg, Thomas Pratt
Publikováno v:
Bio Protoc
The interaction between cell surface heparan sulphate and diffusible ligands such as FGFs is of vital importance for downstream signaling, however, there are few techniques that can be used to investigate this binding event. The ligand and carbohydra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946472288d6789cecc1aefb0922d2db6
https://doi.org/10.21769/bioprotoc.3952
https://doi.org/10.21769/bioprotoc.3952
Autor:
Thomas Pratt, James M. Clegg
Publikováno v:
Bio Protoc
Organotypic slice culture is a powerful technique for exploring the embryonic development of the mammalian brain. In this protocol we describe a basic slice culture technique we have used for two sets of experiments: axon guidance transplant assays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25302c304ec8903b90ab8c7a4f484d00
https://doi.org/10.21769/bioprotoc.3674
https://doi.org/10.21769/bioprotoc.3674
Publikováno v:
Frontiers in Neuroscience, Vol 6 (2012)
The thalamus is essential for sensory perception. In mammals, work on the mouse has taught us most of what we know about how it develops and connects to the cortex. The mature thalamus of all mammalian species comprises numerous anatomically distinct
Externí odkaz:
https://doaj.org/article/cadfd35ffe5a4710b6dab1324d7aabe2
Autor:
James M. Clegg, Ziwen Li, Pablo Hernández-Malmierca, Idoia Quintana-Urzainqui, Zrinko Kozic, David Price
Publikováno v:
Quintana Urzainqui, I, Hernandez-Malmierca, P, Clegg, J, Li, C, Kozic, Z & Price, D 2020, ' The role of the diencephalon in the guidance of thalamocortical axons in mice ', Development . https://doi.org/10.1242/dev.184523
Development (Cambridge, England)
article-version (VoR) Version of Record
Development (Cambridge, England)
article-version (VoR) Version of Record
Thalamocortical axons (TCAs) cross several tissues on their journey to the cortex. Mechanisms must be in place along the route to ensure they connect with their targets in an orderly fashion. The ventral telencephalon acts as an instructive tissue, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f7e8be8e235494be0c7e40c87b3995
https://doi.org/10.1101/763201
https://doi.org/10.1101/763201
Publikováno v:
The Journal of Neuroscience
Heparan sulfate (HS) is a cell surface and extracellular matrix carbohydrate extensively modified by differential sulfation. HS interacts physically with canonical fibroblast growth factor (FGF) proteins that signal through the extracellular signal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c75d417612d8a4a37fd1809565978493
https://pubmed.ncbi.nlm.nih.gov/30617207
https://pubmed.ncbi.nlm.nih.gov/30617207