Zobrazeno 1 - 10
of 92
pro vyhledávání: '"James M. Burns"'
Publikováno v:
Vaccines, Vol 12, Iss 4, p 351 (2024)
Efficacy data on two malaria vaccines, RTS,S and R21, targeting Plasmodium falciparum circumsporozoite protein (PfCSP), are encouraging. Efficacy may be improved by induction of additional antibodies to neutralizing epitopes outside of the central im
Externí odkaz:
https://doaj.org/article/98773ad8df8e4248a9d22c94a8c7f341
Autor:
James M. Burns
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-3 (2018)
Abstract Efforts to develop an effective malaria vaccine have encountered multiple challenges, and have had limited success to date. As the need remains urgent, novel approaches must be explored. One concept that has gained attention uses whole malar
Externí odkaz:
https://doaj.org/article/c1af66e83fc44dcca6242b6a99fb9cef
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232355 (2020)
BackgroundEradication of Plasmodium falciparum malaria will likely require a multivalent vaccine, but the development of a highly efficacious subunit-based formulation has been challenging. We previously showed that production and immunogenicity of t
Externí odkaz:
https://doaj.org/article/492878b5e2494ae68d8f2b78e8ed3a29
Publikováno v:
J Immunol
Plasmodium falciparum merozoite surface protein (PfMSP)2 is a target of parasite-neutralizing Abs. Inclusion of recombinant PfMSP2 (rPfMSP2) as a component of a multivalent malaria vaccine is of interest, but presents challenges. Previously, we used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f4c95ed36d8399a42b45c987773c2c
https://doi.org/10.4049/jimmunol.2000927
https://doi.org/10.4049/jimmunol.2000927
Autor:
Sudipta Das, Suyash Bhatanagar, Joanne M Morrisey, Thomas M Daly, James M Burns, Isabelle Coppens, Akhil B Vaidya
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005647 (2016)
Among the several new antimalarials discovered over the past decade are at least three clinical candidate drugs, each with a distinct chemical structure, that disrupt Na+ homeostasis resulting in a rapid increase in intracellular Na+ concentration ([
Externí odkaz:
https://doaj.org/article/34132c11ef42427098742ad90d4c36a6
Autor:
James M. Burns
Publikováno v:
The American Historical Review. 125:1365-1369
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2c7da719f8afa873ea94b3161553ce2
https://doi.org/10.1093/ahr/rhz1243
https://doi.org/10.1093/ahr/rhz1243
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
Scientific Reports
Scientific Reports
Vaccine trials and cohort studies in Plasmodium falciparum endemic areas indicate that naturally-acquired and vaccine-induced antibodies to merozoite surface protein 2 (MSP2) are associated with resistance to malaria. These data indicate that PfMSP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2bdbd1356c37f4582bfcd04581987cf
http://link.springer.com/article/10.1038/s41598-019-45440-4
http://link.springer.com/article/10.1038/s41598-019-45440-4
Autor:
James M. Burns
Publikováno v:
Tijdschrift voor Mediageschiedenis, Vol 23, Iss 1-2 (2020)
Tijdschrift voor Mediageschiedenis, 23(1-2), 1-27
Tijdschrift voor Mediageschiedenis, 23(1-2), 1-27
This essay evaluates some of the challenges and opportunities posed by comparative history of cinema-going by looking at the history of one understudied world region, Great Britain’s Caribbean colonies. It concludes with a discussion of potential f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e366c646e8f6078ee414d0150a9d70
https://www.tmgonline.nl/article/10.18146/tmg.585/
https://www.tmgonline.nl/article/10.18146/tmg.585/
Autor:
Jr. James M. Burns
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-3 (2018)
BMC Medicine
BMC Medicine
Background The continuing morbidity and mortality associated with infection with malaria parasites highlights the urgent need for a vaccine. The efficacy of sub-unit vaccines tested in clinical trials in malaria-endemic areas has thus far been disapp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dab95740f4b1458400bc47dc756455a
http://link.springer.com/article/10.1186/s12916-018-1197-1
http://link.springer.com/article/10.1186/s12916-018-1197-1
Autor:
James M. Burns
Publikováno v:
Reforming American Government ISBN: 9780429304125
Reforming American Government
Reforming American Government
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91fd1afb884a69ad04abfdf33eefd0cc
https://doi.org/10.4324/9780429304125-10
https://doi.org/10.4324/9780429304125-10
