Zobrazeno 1 - 10
of 68
pro vyhledávání: '"James M. Brase"'
Autor:
Kevin S. McLoughlin, Da Shi, Jeffrey E. Mast, John Bucci, John P. Williams, W. Derek Jones, Derrick Miyao, Luke Nam, Heather L. Osswald, Lev Zegelman, Jonathan Allen, Brian J. Bennion, Amanda K. Paulson, Ruben Abagyan, Martha S. Head, James M. Brase
Generative molecular design (GMD) is an increasingly popular strategy for drug discovery, using machine learning models to propose, evaluate and optimize chemical structures against a set of target design criteria. We present the ATOM-GMD platform, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45cdcb6fae94d7e54a5b854991c78868
https://doi.org/10.1101/2023.02.14.528391
https://doi.org/10.1101/2023.02.14.528391
Autor:
James M. Brase
Publikováno v:
National Virtual Biotechnology Laboratory Symposium: Harnessing the unique strengths of DOE to tackle the biotechnology challenges of COVID-19, October 28, 2020.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3587960878d67ac31555ae2ce6ad4475
https://doi.org/10.2172/1718931
https://doi.org/10.2172/1718931
Autor:
James M. Brase, Thomas S. Rush, Brian J. Bennion, Kevin McLoughlin, Thomas D. Sweitzer, Margaret J. Tse, Jonathan E. Allen, Stacie Calad-Thomson, Claire G. Jeong, Amanda Minnich
Drug-induced liver injury (DILI) is the most common cause of acute liver failure and a frequent reason for withdrawal of candidate drugs during preclinical and clinical testing. An important type of DILI is cholestatic liver injury, caused by buildup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d12110e0bc5b0a03cb79780f563a04
http://arxiv.org/abs/2002.12541
http://arxiv.org/abs/2002.12541
Publikováno v:
Nuclear Non-proliferation and Arms Control Verification ISBN: 9783030295363
Hidden within our rapidly growing global streams of business, scientific, and communications data, is information that can reduce the global danger of nuclear weapons proliferation and use. Significant advances in machine learning, the explosion of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94c1af1940c3f2b58fd24ef2c02a342f
https://doi.org/10.1007/978-3-030-29537-0_20
https://doi.org/10.1007/978-3-030-29537-0_20
Autor:
Steve Langer, Ryan Nora, Jayaraman J. Thiagarajan, Kelli Humbird, Katie Lewis, Brian Van Essen, Brian Spears, Jim Gaffney, Michael Kruse, Barry Chen, J. L. Peterson, Peer-Timo Bremer, James M. Brase, J. E. Field
Publikováno v:
Physics of Plasmas. 25:080901
Machine learning is finding increasingly broad applications in the physical sciences. This most often involves building a model relationship between a dependent, measurable output, and an associated set of controllable, but complicated, independent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e655805fdf5c06580b4cf7e39d266af8
https://doi.org/10.1063/1.5020791
https://doi.org/10.1063/1.5020791
Autor:
James E. Larkin, K. Ho, K. Tsubota, William Lupton, James M. Brase, C. Shelton, Claire E. Max, Paul J. Stomski, D. S. Acton, Donald T. Gavel, Andrea M. Ghez, Scot S. Olivier, Jong R. An, Kenneth Avicola, J. Gathright, Bruce Macintosh, Peter Wizinowich, Olivier Lai
Publikováno v:
Scopus-Elsevier
Adaptive optics (AO) is a technology that corrects in real time for the blurring effects of atmospheric turbulence, in principle allowing Earth‐bound telescopes to achieve their diffraction limit and to “see” as clearly as if they were in space
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332b4a1b03b3538a3ef98467621d69cc
https://doi.org/10.1086/316543
https://doi.org/10.1086/316543
Autor:
L. B. Da Silva, Thomas J. Yorkey, B. J. MacGowan, Stanley Mrowka, David Attwood, Dennis L Matthews, James M. Brase, Erik H. Anderson, James E. Trebes, R. A. London, Gary Stone, Dieter P. Kern, D. Minyard, Jeffrey A. Koch, Troy W. Barbee
Publikováno v:
Optics letters. 17(10)
High-brightness and short-pulse-width ( approximately 200 ps) x-ray lasers offer biologists the possibility of high-resolution three-dimensional imaging of specimens in an aqueous environment without the blurring effects associated with natural motio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab46e5bf839a2f3f6ebf428beb7c694
https://pubmed.ncbi.nlm.nih.gov/19794620
https://pubmed.ncbi.nlm.nih.gov/19794620
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes. 41:943-961
x-Ray computed axial tomography (CT) provides cross-sectional views of materials, components, and assemblies for industrial non-destructive evaluation. We have applied CT imaging to quantitatively measure the 3-D distribution ogf x-ray attenuation at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4344e57265ac84a60e7b076f8e69a131
https://doi.org/10.1016/0883-2889(90)90159-e
https://doi.org/10.1016/0883-2889(90)90159-e
Autor:
Herbert W. Friedman, James M. Brase, J.T. Salmon, B. Bissinger, D. Gavel, K. Waltjen, K. Avicola, Claire E. Max, S. Olivier, J. Morris
Publikováno v:
LEOS '92 Conference Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b99893aa39bd7e4592b512714584e98e
https://doi.org/10.1109/leos.1992.694122
https://doi.org/10.1109/leos.1992.694122
Autor:
James M. Brase, David W. Paglieroni, Sergei Nikolaev, George F. Weinert, Aseneth S. Lopez, Charles W. Grant, Douglas N. Poland
Publikováno v:
SPIE Proceedings.
The Image Content Engine (ICE) is being developed to provide cueing assistance to human image analysts faced with increasingly large and intractable amounts of image data. The ICE architecture includes user configurable feature extraction pipelines w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8ab9161fcc9c5e345225aed3389bb88
https://doi.org/10.1117/12.608828
https://doi.org/10.1117/12.608828