Zobrazeno 1 - 10
of 72
pro vyhledávání: '"James M Ward"'
Publikováno v:
eLife, Vol 8 (2019)
The SWI/SNF complex is a critical regulator of pluripotency in human embryonic stem cells (hESCs), and individual subunits have varied and specific roles during development and in diseases. The core subunit SMARCB1 is required for early embryonic sur
Externí odkaz:
https://doaj.org/article/802f4167aa9246da8c5f3c659268b432
Autor:
A. Clare Sparling, James M. Ward, Kakali Sarkar, Adam Schiffenbauer, Payam Noroozi Farhadi, Michael A. Smith, Saifur Rahman, Kamelia Zerrouki, Frederick W. Miller, Jian-Liang Li, Kerry A. Casey, Lisa G. Rider
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Objectives Serum protein abundance was assessed in adult and juvenile dermatomyositis (DM and JDM) patients to determine differentially regulated proteins, altered pathways, and candidate disease activity biomarkers. Methods Serum protein ex
Externí odkaz:
https://doaj.org/article/5ee387052055449bbf31c595ef8f3253
Publikováno v:
eLife, Vol 7 (2018)
The Glucocorticoid Receptor (GR) alters transcriptional activity in response to hormones by interacting with chromatin at GR binding sites (GBSs) throughout the genome. Our work in human breast cancer cells identifies three classes of GBSs with disti
Externí odkaz:
https://doaj.org/article/f5c6465725fc45508379b37933ff4a19
Autor:
Mikyeong Lee, Abhishek Kaul, James M. Ward, Qiyun Zhu, Marie Richards, Ziyue Wang, Antonio González, Christine G. Parks, Laura E. Beane Freeman, David M. Umbach, Alison A. Motsinger-Reif, Rob Knight, Stephanie J. London
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background Chronic exposure to microorganisms inside homes can impact respiratory health. Few studies have used advanced sequencing methods to examine adult respiratory outcomes, especially continuous measures. We aimed to identify metagenom
Externí odkaz:
https://doaj.org/article/97747b8b6c014deea62feb192a18484e
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29457 (2012)
Spoken language and learned song are complex communication behaviors found in only a few species, including humans and three groups of distantly related birds--songbirds, parrots, and hummingbirds. Despite their large phylogenetic distances, these vo
Externí odkaz:
https://doaj.org/article/311d42692c6946e48b121aeba0770a42
Autor:
Ayland C. Letsinger, James M. Ward, Rick D. Fannin, Debabrata Mahapatra, Matthew F. Bridge, Robert C. Sills, Kevin E. Gerrish, Jerrel L. Yakel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Individuals infected by SARS-CoV-2 are at risk of developing neurological-related post-acute disorders. Disputed epidemiological data indicated nicotine may reduce the severity of infection. Here we find exposure to nicotine in drinking wate
Externí odkaz:
https://doaj.org/article/a94472cf3e3e46a2bce2f15c2e749ed5
Autor:
Mi Kyeong Lee, Cheng-Jian Xu, Megan U. Carnes, Cody E. Nichols, James M. Ward, The BIOS consortium, Sung Ok Kwon, Sun-Young Kim, Woo Jin Kim, Stephanie J. London
Publikováno v:
Clinical Epigenetics, Vol 11, Iss 1, Pp 1-12 (2019)
Abstract Background Ambient air pollution is associated with numerous adverse health outcomes, but the underlying mechanisms are not well understood; epigenetic effects including altered DNA methylation could play a role. To evaluate associations of
Externí odkaz:
https://doaj.org/article/ab520356f88c46fea95bb623a309c80d
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 522-539.e6 (2019)
Summary: RNA localization is one mechanism neurons use to spatially and temporally regulate gene expression at synapses. Here, we test the hypothesis that cells exhibiting distinct forms of synaptic plasticity will have differences in dendritically l
Externí odkaz:
https://doaj.org/article/dd9bbd6cf1f0489b968a7648a153599e
Autor:
Nolan G. Gokey, James M. Ward, Eric J. Milliman, Leesa J. Deterding, Kevin W. Trotter, Trevor K. Archer
The Chromatosome superstructure, comprised of core histone containing nucleosomes and linker histones, act in concert as physical barriers to genetic material in the mammalian nucleus to trans-acting factors. Appropriate arrangement, composition, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4dab22b753a4b3ef14ea5c39aaf37b4
https://doi.org/10.1101/2023.05.14.540702
https://doi.org/10.1101/2023.05.14.540702
Autor:
Ayland C. Letsinger, James M. Ward, Rick D. Fannin, Debabrata Mahapatra, Matthew F. Bridge, Robert C. Sills, Kevin E. Gerrish, Jerrel L. Yakel
Publikováno v:
Research square.
Individuals infected by SARS-CoV-2 are at risk of developing neurological-related post-acute disorders. Disputed epidemiological data indicated nicotine may reduce the severity of infection. Here we find exposure to nicotine in drinking water does no