Zobrazeno 1 - 10
of 130
pro vyhledávání: '"James M Pipas"'
Autor:
Coyne Drummond, Mary E Gebhardt, Maria Teresa Sáenz Robles, Giovanna Carpi, Isaiah Hoyer, Andrzej Pastusiak, Michael R Reddy, Douglas E Norris, James M Pipas, Ethan K Jackson
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0231061 (2020)
Monitoring the presence and spread of pathogens in the environment is of critical importance. Rapid detection of infectious disease outbreaks and prediction of their spread can facilitate early responses of health agencies and reduce the severity of
Externí odkaz:
https://doaj.org/article/d94b2a2f34cf4caab60a84f845f2e914
Publikováno v:
PLoS Pathogens, Vol 15, Iss 1, p e1007505 (2019)
Polyomavirus BKV is highly prevalent among humans. The virus establishes an asymptomatic persistent infection in the urinary system in healthy people, but uncontrolled productive infection of the virus in immunocompromised patients can lead to seriou
Externí odkaz:
https://doaj.org/article/573af5c84fd84e49b94ee9948f9e3df2
Autor:
Andrzej Pastusiak, Michael R. Reddy, Xiaoji Chen, Isaiah Hoyer, Jack Dorman, Mary E. Gebhardt, Giovanna Carpi, Douglas E. Norris, James M. Pipas, Ethan K. Jackson
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract The Anopheles gambiae 1000 Genomes (Ag1000G) Consortium previously utilized deep sequencing methods to catalogue genetic diversity across African An. gambiae populations. We analyzed the complete datasets of 1142 individually sequenced mosqu
Externí odkaz:
https://doaj.org/article/5969504ef8fe4cfabc70da61814184a0
Autor:
Christopher B Buck, Koenraad Van Doorslaer, Alberto Peretti, Eileen M Geoghegan, Michael J Tisza, Ping An, Joshua P Katz, James M Pipas, Alison A McBride, Alvin C Camus, Alexa J McDermott, Jennifer A Dill, Eric Delwart, Terry F F Ng, Kata Farkas, Charlotte Austin, Simona Kraberger, William Davison, Diana V Pastrana, Arvind Varsani
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005574 (2016)
Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches
Externí odkaz:
https://doaj.org/article/7739ad4591ff4b3b9ba8b0164dfb5663
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26019 (2011)
The retinoblastoma tumor suppressor (pRb) regulates cell cycle entry, progression and exit by controlling the activity of the E2F-family of transcription factors. During cell cycle exit pRb acts as a transcriptional repressor by associating with E2F
Externí odkaz:
https://doaj.org/article/b1d2c61c130442b3b158d0b3aa45993d
Autor:
Ping An, Maria Teresa Sáenz Robles, Paul G. Cantalupo, Abhijit S. Naik, Rachel Sealfon, Michael J. Imperiale, James M. Pipas
Publikováno v:
Journal of Virology. 97
Cultured primary human cells provide powerful tools for the study of viral infectious cycles and host virus interactions. In the case of BKV-associated nephropathy, viral replication occurs primarily in the proximal tubule epithelia in the kidney.
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-15 (2021)
NPJ Genomic Medicine
NPJ Genomic Medicine
Oncogenic human papillomavirus (HPV) genomes are often integrated into host chromosomes in HPV-associated cancers. HPV genomes are integrated either as a single copy, or as tandem repeats of viral DNA interspersed with, or without, host DNA. Integrat
Autor:
Adrie van Bokhoven, Michelle Murkowski, Paul G. Cantalupo, Alexis M. Duray, Maria Teresa Sáenz Robles, Michael J. Imperiale, Melissa Freeland, Alisa J. Stephens-Shields, James M. Pipas
Publikováno v:
Virus Genes
The question of whether some cases of interstitial cystitis may have an infectious etiology has been debated for some time. Previous studies have looked for the presence of certain specific viruses, but generally did not use the types of sensitive an
Autor:
James M. Pipas, Paul G. Cantalupo
Publikováno v:
Current Opinion in Virology. 39:41-48
Next generation sequencing (NGS) technologies provide an increasingly important avenue for detecting known viruses, and for discovering novel viruses present in clinical or environmental samples. Several computational pipelines capable of identifying
Autor:
Ping An, Wenshan Zheng, Alexis M. Duray, Maria Teresa Sáenz-Robles, James M. Pipas, David A. Weitz, Paul G. Cantalupo
Publikováno v:
J Virol
BK virus (BKV) is a human polyomavirus that is generally harmless but can cause devastating disease in immunosuppressed individuals. BKV infection of renal cells is a common problem for kidney transplant patients undergoing immunosuppressive therapy.