Zobrazeno 1 - 10
of 45
pro vyhledávání: '"James M Otis"'
Autor:
Roger I Grant, Elizabeth M Doncheck, Kelsey M Vollmer, Kion T Winston, Elizaveta V Romanova, Preston N Siegler, Heather Holman, Christopher W Bowen, James M Otis
Publikováno v:
eLife, Vol 10 (2021)
Non-overlapping cell populations within dorsomedial prefrontal cortex (dmPFC), defined by gene expression or projection target, control dissociable aspects of reward seeking through unique activity patterns. However, even within these defined cell po
Externí odkaz:
https://doaj.org/article/ccc94d2bcad448289269753f9ea3d1a1
Autor:
Kelsey M. Vollmer, Lisa M. Green, Roger I. Grant, Kion T. Winston, Elizabeth M. Doncheck, Christopher W. Bowen, Jacqueline E. Paniccia, Rachel E. Clarke, Annika Tiller, Preston N. Siegler, Bogdan Bordieanu, Benjamin M. Siemsen, Adam R. Denton, Annaka M. Westphal, Thomas C. Jhou, Jennifer A. Rinker, Jacqueline F. McGinty, Michael D. Scofield, James M. Otis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Abstract Suppression of dangerous or inappropriate reward-motivated behaviors is critical for survival, whereas therapeutic or recreational opioid use can unleash detrimental behavioral actions and addiction. Nevertheless, the neuronal systems that s
Externí odkaz:
https://doaj.org/article/f0bc29247a204771859cdb2512d2b3cb
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 4146-4156 (2022)
Astrocytes are critical components of neural circuits positioned in close proximity to the synapse, allowing them to rapidly sense and respond to neuronal activity. One repeatedly observed biomarker of astroglial activation is an increase in intracel
Externí odkaz:
https://doaj.org/article/90afc89d4ab84d898e5c38595704b08d
Autor:
Kelsey M. Vollmer, Lisa M. Green, Roger I. Grant, Kion T. Winston, Elizabeth M. Doncheck, Christopher W. Bowen, Jacqueline E. Paniccia, Rachel E. Clarke, Annika Tiller, Preston N. Siegler, Bogdan Bordieanu, Benjamin M. Siemsen, Adam R. Denton, Annaka M. Westphal, Thomas C. Jhou, Jennifer A. Rinker, Jacqueline F. McGinty, Michael D. Scofield, James M. Otis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a10243d94f984facbf4098b64656b615
Autor:
Benjamin M. Siemsen, Sarah M. Barry, Kelsey M. Vollmer, Lisa M. Green, Ashley G. Brock, Annaka M. Westphal, Raven A. King, Derek M. DeVries, James M. Otis, Christopher W. Cowan, Michael D. Scofield
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
BackgroundPrelimbic cortical projections to the nucleus accumbens core are critical for cue-induced cocaine seeking, but the identity of the accumbens neuron(s) targeted by this projection, and the transient neuroadaptations contributing to relapse w
Externí odkaz:
https://doaj.org/article/b5fc6239108848da9c09372d755b51fc
Autor:
Kelsey M. Vollmer, Elizabeth M. Doncheck, Roger I. Grant, Kion T. Winston, Elizaveta V. Romanova, Christopher W. Bowen, Preston N. Siegler, Lisa M. Green, Ana-Clara Bobadilla, Ivan Trujillo-Pisanty, Peter W. Kalivas, James M. Otis
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
Multiphoton microscopy is one of several new technologies providing unprecedented insight into the activity dynamics and function of neural circuits. Unfortunately, some of these technologies require experimentation in head-restrained animals, limiti
Externí odkaz:
https://doaj.org/article/e849e26865d34ed0bb63394d673d8812
Autor:
Saurabh S. Kokane, Robert D. Cole, Bogdan Bordieanu, Chevin M. Ray, Ishraq A. Haque, James M. Otis, Jacqueline F. McGinty
Publikováno v:
The Journal of Neuroscience. 43:4019-4032
Dysregulation of the input from the prefrontal cortex (PFC) to the nucleus accumbens (NAc) contributes to cue-induced opioid seeking but the heterogeneity in, and regulation of, prelimbic (PL)-PFC to NAc (PL->NAc) neurons that are altered has not bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::068fa619e2d664092d3ef6ffd46b0641
https://doi.org/10.1523/jneurosci.0108-23.2023
https://doi.org/10.1523/jneurosci.0108-23.2023
Autor:
Jacqueline F. McGinty, James M. Otis
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2020)
The paraventricular thalamic nucleus (PVT) is highly interconnected with brain areas that control reward-seeking behavior. Despite this known connectivity, broad manipulations of PVT often lead to mixed, and even opposing, behavioral effects, cloudin
Externí odkaz:
https://doaj.org/article/213dc20678b64fddba28339b51a1551a
Autor:
James M. Otis, Michael K. Fitzgerald, Hanna Yousuf, Jake L. Burkard, Matthew Drake, Devin Mueller
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Presentation of drug-associated cues provokes craving and drug seeking, and elimination of these associative memories would facilitate recovery from addiction. Emotionally salient memories are maintained during retrieval, as particular pharmacologic
Externí odkaz:
https://doaj.org/article/9ee29c24959b44b1a2c38e2548927b28
Autor:
Kelsey M. Vollmer, Lisa M. Green, Jacqueline E. Paniccia, Roger I. Grant, Kion T. Winston, Sophie Buchmaier, Elizabeth M. Doncheck, Rachel E. Clarke, Michael D. Scofield, James M. Otis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3a79984484bf8cf1b47606ab49a6a2e
https://doi.org/10.2139/ssrn.4417783
https://doi.org/10.2139/ssrn.4417783
