Zobrazeno 1 - 10
of 127
pro vyhledávání: '"James M Mullin"'
Autor:
Ariel Shepley-McTaggart, Cari A Sagum, Isabela Oliva, Elizabeth Rybakovsky, Katie DiGuilio, Jingjing Liang, Mark T Bedford, Joel Cassel, Marius Sudol, James M Mullin, Ronald N Harty
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0251955 (2021)
Newly emerged SARS-CoV-2 is the cause of an ongoing global pandemic leading to severe respiratory disease in humans. SARS-CoV-2 targets epithelial cells in the respiratory tract and lungs, which can lead to amplified chloride secretion and increased
Externí odkaz:
https://doaj.org/article/2040963e947d4968bd423ee2b28d9917
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242536 (2020)
Retinoic acid (RA) has been shown to improve epithelial and endothelial barrier function and development and even suppress damage inflicted by inflammation on these barriers through regulating immune cell activity. This paper thus sought to determine
Externí odkaz:
https://doaj.org/article/971496afaf204a1fb638b2e412ca90c2
Autor:
James M Mullin, Katherine M Diguilio, Mary C Valenzano, Rachael Deis, Sunil Thomas, E Peter Zurbach, Shaheed Abdulhaqq, Luis J Montaner
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0170306 (2017)
Human semen has the potential to modulate the epithelial mucosal tissues it contacts, as seminal plasma (SP) is recognized to contain both pro- and anti-barrier components, yet its effects on epithelial barrier function are largely unknown. We addres
Externí odkaz:
https://doaj.org/article/f7eba496fdd641c1a93b4aa132a2a9fa
Autor:
Mary Carmen Valenzano, Katherine DiGuilio, Joanna Mercado, Mimi Teter, Julie To, Brendan Ferraro, Brittany Mixson, Isabel Manley, Valerissa Baker, Beverley A Moore, Joshua Wertheimer, James M Mullin
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133926 (2015)
The micronutrients zinc, quercetin, butyrate, indole and berberine were evaluated for their ability to induce remodeling of epithelial tight junctions (TJs) and enhance barrier integrity in the CACO-2 gastrointestinal epithelial cell culture model. A
Externí odkaz:
https://doaj.org/article/f3fdcac2b9c74a16ae3e086d87c76d4b
Autor:
Joanna Mercado, Mary Carmen Valenzano, Cameron Jeffers, Jason Sedlak, Marina K Cugliari, Eleni Papanikolaou, Jacob Clouse, Jingya Miao, Nina E Wertan, James M Mullin
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78775 (2013)
Amid an increasing number of reports in the literature concerning epithelial barrier enhancement by various nutrient compounds, there has never been a study performing side-by-side comparisons of these agents in a single epithelial model. We compare
Externí odkaz:
https://doaj.org/article/1cd0a19dcc364bdaa97b299debe03b35
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3452 (2024)
Disease modifiers, whether from cancer, sepsis, systemic inflammation, or microbial pathogens, all appear to induce epithelial barrier leak, with induced changes of the Tight Junctional (TJ) complex being pivotal to the process. This leak—and the e
Externí odkaz:
https://doaj.org/article/c333f7c13ac64b70bdac09ddfdc32298
Autor:
Elizabeth Rybakovsky, Katherine M. DiGuilio, Mary Carmen Valenzano, Sophie Geagan, Kaithlyn Pham, Ronald N. Harty, James M. Mullin
Publikováno v:
Physiological Reports, Vol 11, Iss 7, Pp n/a-n/a (2023)
Abstract Using the 16HBE 14o‐ human airway epithelial cell culture model, calcitriol (Vitamin D) was shown to improve barrier function by two independent metrics – increased transepithelial electrical resistance (TER) and reduced transepithelial
Externí odkaz:
https://doaj.org/article/97551726850c4e4787451875ffb06e47
Autor:
Katherine M. DiGuilio, Elizabeth Rybakovsky, Yoongyeong Baek, Mary Carmen Valenzano, James M. Mullin
Publikováno v:
Experimental Lung Research. :1-14
Autor:
Elizabeth Rybakovsky, Katherine M. DiGuilio, Mary Carmen Valenzano, Sophie Geagan, Kaithlyn Pham, Ronald N. Harty, James M. Mullin
Publikováno v:
Physiological Reports. 11
Autor:
Ayyappan K. Rajasekaran, James M. Mullin, James M. Leatherman, Mansoor M. Ahmed, Anna E. Reeves, Jeffrey F. Harper, Susanne B. Nicholas, Charles Lassman, Anna Skay, Landon J. Inge, Cromwell E. Espineda, Daniel G. Wolle, Thu P. Huynh, Sigrid A. Rajasekaran
Epithelial-to-mesenchymal transition (EMT) is an important developmental process, participates in tissue repair, and occurs during pathologic processes of tumor invasiveness, metastasis, and tissue fibrosis. The molecular mechanisms leading to EMT ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cbde3d69e62f7fe378d302e6466d92
https://doi.org/10.1158/1535-7163.c.6531620
https://doi.org/10.1158/1535-7163.c.6531620