Zobrazeno 1 - 10
of 127
pro vyhledávání: '"James M, Mullin"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3452 (2024)
Disease modifiers, whether from cancer, sepsis, systemic inflammation, or microbial pathogens, all appear to induce epithelial barrier leak, with induced changes of the Tight Junctional (TJ) complex being pivotal to the process. This leak—and the e
Externí odkaz:
https://doaj.org/article/c333f7c13ac64b70bdac09ddfdc32298
Autor:
Elizabeth Rybakovsky, Katherine M. DiGuilio, Mary Carmen Valenzano, Sophie Geagan, Kaithlyn Pham, Ronald N. Harty, James M. Mullin
Publikováno v:
Physiological Reports, Vol 11, Iss 7, Pp n/a-n/a (2023)
Abstract Using the 16HBE 14o‐ human airway epithelial cell culture model, calcitriol (Vitamin D) was shown to improve barrier function by two independent metrics – increased transepithelial electrical resistance (TER) and reduced transepithelial
Externí odkaz:
https://doaj.org/article/97551726850c4e4787451875ffb06e47
Autor:
Katherine M. DiGuilio, Elizabeth Rybakovsky, Yoongyeong Baek, Mary Carmen Valenzano, James M. Mullin
Publikováno v:
Experimental Lung Research. :1-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d59b1eebbc5efc1e9837d79418c019fb
https://doi.org/10.1080/01902148.2023.2193637
https://doi.org/10.1080/01902148.2023.2193637
Autor:
Ariel Shepley-McTaggart, Cari A Sagum, Isabela Oliva, Elizabeth Rybakovsky, Katie DiGuilio, Jingjing Liang, Mark T Bedford, Joel Cassel, Marius Sudol, James M Mullin, Ronald N Harty
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0251955 (2021)
Newly emerged SARS-CoV-2 is the cause of an ongoing global pandemic leading to severe respiratory disease in humans. SARS-CoV-2 targets epithelial cells in the respiratory tract and lungs, which can lead to amplified chloride secretion and increased
Externí odkaz:
https://doaj.org/article/2040963e947d4968bd423ee2b28d9917
Autor:
Katherine M. DiGuilio, Elizabeth Rybakovsky, Reza Abdavies, Romy Chamoun, Colleen A. Flounders, Ariel Shepley-McTaggart, Ronald N. Harty, James M. Mullin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 6, p 2995 (2022)
The published literature makes a very strong case that a wide range of disease morbidity associates with and may in part be due to epithelial barrier leak. An equally large body of published literature substantiates that a diverse group of micronutri
Externí odkaz:
https://doaj.org/article/c1a9938df5c743cdb5c586e2a89a26c2
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242536 (2020)
Retinoic acid (RA) has been shown to improve epithelial and endothelial barrier function and development and even suppress damage inflicted by inflammation on these barriers through regulating immune cell activity. This paper thus sought to determine
Externí odkaz:
https://doaj.org/article/971496afaf204a1fb638b2e412ca90c2
Autor:
Elizabeth Rybakovsky, Katherine M. DiGuilio, Mary Carmen Valenzano, Sophie Geagan, Kaithlyn Pham, Ronald N. Harty, James M. Mullin
Publikováno v:
Physiological Reports. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d131f94d49fc257e8de4185e84eb629
https://doi.org/10.14814/phy2.15592
https://doi.org/10.14814/phy2.15592
Autor:
Ayyappan K. Rajasekaran, James M. Mullin, James M. Leatherman, Mansoor M. Ahmed, Anna E. Reeves, Jeffrey F. Harper, Susanne B. Nicholas, Charles Lassman, Anna Skay, Landon J. Inge, Cromwell E. Espineda, Daniel G. Wolle, Thu P. Huynh, Sigrid A. Rajasekaran
Epithelial-to-mesenchymal transition (EMT) is an important developmental process, participates in tissue repair, and occurs during pathologic processes of tumor invasiveness, metastasis, and tissue fibrosis. The molecular mechanisms leading to EMT ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39cbde3d69e62f7fe378d302e6466d92
https://doi.org/10.1158/1535-7163.c.6531620
https://doi.org/10.1158/1535-7163.c.6531620
Autor:
Ayyappan K. Rajasekaran, James M. Mullin, James M. Leatherman, Mansoor M. Ahmed, Anna E. Reeves, Jeffrey F. Harper, Susanne B. Nicholas, Charles Lassman, Anna Skay, Landon J. Inge, Cromwell E. Espineda, Daniel G. Wolle, Thu P. Huynh, Sigrid A. Rajasekaran
Supplementary Data from Na,K-ATPase Subunits as Markers for Epithelial-Mesenchymal Transition in Cancer and Fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4174e6cb63ec9ca2d6f2d281a4faae66
https://doi.org/10.1158/1535-7163.22484855.v1
https://doi.org/10.1158/1535-7163.22484855.v1
Publikováno v:
Journal of Pharmacokinetics and Pharmacodynamics
A physiologically based model describing the dissolution, diffusion, and transfer of drug from the intra-articular (IA) space to the plasma, was developed for GastroPlus® v9.8. The model is subdivided into compartments representing the synovial flui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c729c5b6913317fd70841476d14d277b
https://doi.org/10.1007/s10928-021-09781-w
https://doi.org/10.1007/s10928-021-09781-w