Zobrazeno 1 - 10
of 107
pro vyhledávání: '"James L. Schardein"'
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 95:160-174
To demonstrate reproductive safety of a new commercial product for reducing the risk of preterm birth, HPC (17α-hydroxyprogesterone caproate, Makena; manufactured by Baxter Pharmaceutical Solutions, Bloomington IN for Ther-Rx Corporation, St. Louis,
Autor:
James L. Schardein
Publikováno v:
Journal of Toxicology: Toxin Reviews. 15:369-391
(1996). Naturally Occurring Teratogens. Journal of Toxicology: Toxin Reviews: Vol. 15, No. 4, pp. 369-391.
Publikováno v:
Teratology. 50:387-394
The developmental toxicity of the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, atorvastatin, was investigated in pregnant rats and rabbits given daily oral doses during organogenesis. Rats received 0, 10, 100, or 300 mg/kg on
Publikováno v:
Fundamental and Applied Toxicology. 23:370-376
Studies reported here assessed the potential adverse effects of silicone gel, Dow Corning Q7-2159A, on general reproduction and fetal development in male and female Charles River CD rats and New Zealand white rabbits. Two control and three treatment
Publikováno v:
Toxicological Sciences. 23:377-381
Reproductive and Developmental Toxicity Studies of Silicone Elastomer Q7-2423/Q7-2551 in Rats and Rabbits. Siddiqui, W. H., Schardein, J. L., Cassidy, S. L., and Meeks, R. G. (1994). Fundam. Appl. Toxicol. 23, 377-381. The purpose of these studies wa
Publikováno v:
Toxicological Sciences. 21:355-365
The neurotoxic potential of N,N-diethyl-m-toluamide (DEET) was evaluated following acute oral administration or following multigeneration plus chronic dietary administration to the rat. For the acute study, rats were administered undiluted DEET at do
Publikováno v:
Fundamental and Applied Toxicology. 16:490-494
Rats received diets containing average daily doses of 0, 50, 150, and 500 mg/kg/day of hexamethylenediamine over two generations. Although no treatment-related mortality was observed in any of the groups, the weight gain of adults and pups was slight
Publikováno v:
Toxicological Sciences. 16:31-40
The purpose of this study was to determine the effect of piroctone olamine, an antidandruff active, on reproductive performance, fertility, parturition, and neonatal viability and growth. Piroctone olamine was administered orally by gavage to three g
Autor:
Mark S. Swanson, Susan L. Schmitt, Patrick Beatty, Richard H. McKee, Zachary A. Wong, James L. Schardein, Ceinwen A. Schreiner
Publikováno v:
Toxicology and Industrial Health. 6:441-460
Catalytic reforming is a refining process that converts naphthenes to aromatics by dehydrogenation to make higher octane gasoline blending components. A portion of this wide boiling range hydrocarbon stream can be separated by distillation and used f