Zobrazeno 1 - 9
of 9
pro vyhledávání: '"James L. Overton"'
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundChloroquine (CQ) and its derivative hydroxychloroquine (HCQ) have recently emerged as potential antiviral and immunomodulatory options for the treatment of 2019 coronavirus disease (COVID-19). To examine the safety profiles of these medicat
Externí odkaz:
https://doaj.org/article/9cd2795f7b584c27af4c17ccabb8e885
Autor:
Lu Ren, Raghavender R. Gopireddy, Guy Perkins, Hao Zhang, Valeriy Timofeyev, Yankun Lyu, Daphne A. Diloretto, Pauline Trinh, Padmini Sirish, James L. Overton, Wilson Xu, Nathan Grainger, Yang K. Xiang, Elena N. Dedkova, Xiao-Dong Zhang, Ebenezer N. Yamoah, Manuel F. Navedo, Phung N. Thai, Nipavan Chiamvimonvat
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 119, iss 36
The sinoatrial node (SAN), the leading pacemaker region, generates electrical impulses that propagate throughout the heart. SAN dysfunction with bradyarrhythmia is well documented in heart failure (HF). However, the underlying mechanisms are not comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b736e79e349d7066dd46a6a8dcb6915a
https://pubmed.ncbi.nlm.nih.gov/36044551
https://pubmed.ncbi.nlm.nih.gov/36044551
Autor:
James L. Overton, Padmini Sirish, Carol E. Nader, Jun Yang, Uma N Srivatsa, Nipavan Chiamvimonvat, Bob Kiaii, Bruce D. Hammock
Publikováno v:
Circulation Research. 129
Introduction: Atrial fibrillation (AF) represents one of the most common arrhythmias seen clinically, yet, current treatment paradigms have proven largely inadequate. One of the main contributors to the pathophysiology of AF is inflammation. Hence, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb25aaa1baac4d915e666ab234e9683
https://doi.org/10.1161/res.129.suppl_1.p476
https://doi.org/10.1161/res.129.suppl_1.p476
Autor:
Wilson Xu, Carol E. Nader, Bruce D. Hammock, Jun Yang, Phung N. Thai, Aldrin V. Gomes, Padmini Sirish, Michael J. Haddad, Lu Ren, Valeriy Timofeyev, Nipavan Chiamvimonvat, James L. Overton
Publikováno v:
Cardiovascular drugs and therapy.
Purpose Nonsteroidal anti-inflammatory drugs (NSAIDs) are among one of the most commonly prescribed medications for pain and inflammation. Diclofenac (DIC) is a commonly prescribed NSAID that is known to increase the risk of cardiovascular diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d234a648e0345edc805edd95656d80b
https://pubmed.ncbi.nlm.nih.gov/34499283
https://pubmed.ncbi.nlm.nih.gov/34499283
Autor:
Hillary K.J. Kao, Dalyir I. Pretto, Alexander A. Merleev, James L. Overton, Emanual Michael Maverakis, Sergey Yechikov, Deborah K. Lieu, Che-Wei Chang, Yao Hui Sun, James W. Chan, Nipavan Chiamvimonvat
Publikováno v:
Stem Cells
Stem cells (Dayton, Ohio), vol 38, iss 1
Stem cells (Dayton, Ohio), vol 38, iss 1
Genetically encoded fluorescent voltage indicators, such as ArcLight, have been used to report action potentials (APs) in human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). However, the ArcLight expression, in all cases, relied o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd20f56a43f14d956497ea2731aaec2
https://doi.org/10.1002/stem.3085
https://doi.org/10.1002/stem.3085
Publikováno v:
Journal of Cardiology
Journal of cardiology, vol 77, iss 5
Journal of cardiology, vol 77, iss 5
Highlights • The usage of antihypertensive drugs is not associated with the risk and severity of COVID-19. • Hypertensive patients with COVID-19 benefit from prior usage of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdb1f34e2b598ca4722e33f97d982f2
http://europepmc.org/articles/PMC7605745
http://europepmc.org/articles/PMC7605745
Autor:
Lu Ren, Alyssa Panitch, Harkanwalpreet Sodhi, Phung N. Thai, Kit S. Lam, Carol E. Nader, Tima Dehghani, Nipavan Chiamvimonvat, Padmini Sirish, Xiaocen Li, James L. Overton, Valeriy Timofeyev
Publikováno v:
Cardiovasc Res
Cardiovascular research, vol 118, iss 1
Cardiovascular research, vol 118, iss 1
Author(s): Dehghani, Tima; Thai, Phung N; Sodhi, Harkanwalpreet; Ren, Lu; Sirish, Padmini; Nader, Carol E; Timofeyev, Valeriy; Overton, James L; Li, Xiaocen; Lam, Kit S; Chiamvimonvat, Nipavan; Panitch, Alyssa | Abstract: AimsOne of the hallmarks of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db4bcc6618876334e7d7e860d5c7dc1
https://europepmc.org/articles/PMC8932156/
https://europepmc.org/articles/PMC8932156/
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology
Background Chloroquine (CQ) and its derivative hydroxychloroquine (HCQ) have recently emerged as potential antiviral and immunomodulatory options for the treatment of 2019 coronavirus disease (COVID-19). To examine the safety profiles of these medica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412d1ad204707d1708104f57dc8f0667
https://doi.org/10.3389/fphar.2020.562777
https://doi.org/10.3389/fphar.2020.562777
Publikováno v:
medRxiv
BackgroundRecently, chloroquine (CQ) and its derivative hydroxychloroquine (HCQ) have emerged as potential antiviral and immunomodulatory options for the treatment of 2019 coronavirus disease (COVID-19). To examine the safety profiles of these medica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d318dc835889d58995cb67455e7c9a