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of 3
pro vyhledávání: '"James L. Meservy"'
Autor:
Vera Gorbunova, Zoltan Sandor, Andrei Seluanov, John H. Wilson, James L. Meservy, Vincent Dion
Publikováno v:
Molecular and Cellular Biology. 23:4485-4493
Despite substantial progress in understanding the mechanism by which expanded CTG/CAG trinucleotide repeats cause neurodegenerative diseases, little is known about the basis for repeat instability itself. By taking advantage of a novel phenomenon, we
Autor:
Gerald M. Adair, R. Geoffrey Sargent, Rodney S. Nairn, James L. Meservy, Brian D. Perkins, Zsofia Intody, John H. Wilson, April E. Kilburn
Publikováno v:
Nucleic Acids Research. 28:3771-3778
Spontaneous recombination between direct repeats at the adenine phosphoribosyltransferase (APRT) locus in ERCC1-deficient cells generates a high frequency of rearrangements that are dependent on the process of homologous recombination, suggesting tha
Autor:
Robert D. Wells, Gregory J. McKenzie, James L. Meservy, John H. Wilson, Ravi R. Iyer, R. Geoffrey Sargent, Fung Chan
Publikováno v:
Molecular and cellular biology. 23(9)
Expansion of CTG triplet repeats in the 3' untranslated region of the DMPK gene causes the autosomal dominant disorder myotonic dystrophy. Instability of CTG repeats is thought to arise from their capacity to form hairpin DNA structures. How these st