Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James L. Mather"'
Autor:
Sergei I. Ochkur, Randall Killingsworth, Donald Archibald, Salman Siddiqui, Michael E. Bozik, Calman Prussin, James L. Mather, Elizabeth A. Jacobsen, Reynold A. Panettieri, Steven I. Dworetzky
Publikováno v:
Idiopathic interstitial pneumonias.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488df6b0950fb05406a9666d459b5264
https://doi.org/10.1183/13993003.congress-2021.rct2900
https://doi.org/10.1183/13993003.congress-2021.rct2900
Autor:
Donald Archibald, Dan Moore, Hiroshi Mitsumoto, James L. Mather, Albert C. Ludolph, Stacy A. Rudnicki, Thomas Petzinger, Leonard H. van den Berg, Michael E. Bozik, Merit Cudkowicz, Bing Zhang, Benjamin Rix Brooks
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 15:406-413
Our objective was to compare the phase II and phase III (EMPOWER) studies of dexpramipexole in ALS and evaluate potential EMPOWER responder subgroups and biomarkers based on significant inter-study population differences. In a post hoc analysis, we c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a312d1187f1ca32d0fac8c02c4ae10f9
https://doi.org/10.3109/21678421.2014.943672
https://doi.org/10.3109/21678421.2014.943672
Publikováno v:
The Journal of Clinical Pharmacology. 51:1177-1185
Dexpramipexole (KNS-760704; [6R]-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine) is a novel synthetic amino-benzothiazole in development for the treatment of amyotrophic lateral sclerosis (ALS). Preclinical studies have shown that dexpramipex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26aa3ddf78c63d91d38d81113698e532
https://doi.org/10.1177/0091270010379412
https://doi.org/10.1177/0091270010379412
Autor:
David A. Schoenfeld, Evan Ingersoll, Jeremy M. Shefner, Mary C. Sullivan, Dan H. Moore, Juliet Moritz, Merit Cudkowicz, Valentin K. Gribkoff, Michael E. Bozik, Donald Archibald, Robert G. Miller, James L. Mather, Craig Amburgey, Hiroshi Mitsumoto
Publikováno v:
Nature medicine. 17(12)
Amyotrophic lateral sclerosis (ALS) is characterized by upper and lower motor neuron dysfunction and loss, rapidly progressive muscle weakness, wasting and death. Many factors, including mitochondrial dysfunction, may contribute to ALS pathogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73104f21dfd9fd2123bdf0a311719e9
https://pubmed.ncbi.nlm.nih.gov/23534617
https://pubmed.ncbi.nlm.nih.gov/23534617