Zobrazeno 1 - 10
of 48
pro vyhledávání: '"James L. Kenyon"'
Publikováno v:
Cell Calcium. 43:388-404
We recorded Ca2+ current and intracellular Ca2+ ([Ca2+](i)) in isolated adult rat dorsal root ganglion (DRG) neurons at 20 and 30 degrees C. In neurons bathed in tetraethylammonium and dialyzed with cesium, warming reduced resting [Ca2+](i) from 87 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d45b1cdced03ec33b70d674d19ee5be
https://doi.org/10.1016/j.ceca.2007.07.001
https://doi.org/10.1016/j.ceca.2007.07.001
Autor:
Neal Fleming, R. Partain, James L. Kenyon, S. H. Kang, Seungil Ro, Kathleen D. Keef, A. M. Farrelly, Tamas Ordog, Kenton M. Sanders
Publikováno v:
Biochemical and Biophysical Research Communications. 345:1342-1349
K(V)11.1 (HERG) channels contribute to membrane potential in a number of excitable cell types. We cloned a variant of K(V)11.1 from human jejunum containing a 171 bp deletion spanning exons 3 and 4. Expression of a full-length cDNA clone containing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbecc7d3ae40e761f7e4ab84cf9167f7
https://doi.org/10.1016/j.bbrc.2006.05.032
https://doi.org/10.1016/j.bbrc.2006.05.032
Publikováno v:
The Journal of General Physiology
The aim of the present study was to provide a mechanistic insight into how phosphatase activity influences calcium-activated chloride channels in rabbit pulmonary artery myocytes. Calcium-dependent Cl- currents (I(ClCa)) were evoked by pipette soluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c2f5aaa377a1e9fe02274d79ce93e6b
https://doi.org/10.1085/jgp.200609507
https://doi.org/10.1085/jgp.200609507
Autor:
J. M. McHugh, James L. Kenyon
Publikováno v:
American Journal of Physiology-Cell Physiology. 286:C342-C348
We wrote a program that runs as a Microsoft Excel spreadsheet to calculate the diffusion of Ca2+in a spherical cell in the presence of a fixed Ca2+buffer and two diffusible Ca2+buffers, one of which is considered to be a fluorescent Ca2+indicator. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e007d2a4cc38502e097f1b85279d1329
https://doi.org/10.1152/ajpcell.00270.2003
https://doi.org/10.1152/ajpcell.00270.2003
Publikováno v:
American Journal of Physiology-Cell Physiology. 281:C1512-C1523
Localized Ca2+transients resulting from inositol trisphosphate (IP3)-dependent Ca2+release couple to spontaneous transient outward currents (STOCs) in murine colonic myocytes. Confocal microscopy and whole cell patch-clamp techniques were used to inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae2f41865c944e6512da0f5a095dacf5
https://doi.org/10.1152/ajpcell.2001.281.5.c1512
https://doi.org/10.1152/ajpcell.2001.281.5.c1512
Publikováno v:
The Journal of Physiology. 533:341-355
1. Two components of voltage-gated, inward currents were observed from murine colonic myocytes. One component had properties of L-type Ca(2+) currents and was inhibited by nicardipine (5 x 10(-7) M). A second component did not 'run down' during dialy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82376c0cad6afce8848890c61c11fa8b
https://doi.org/10.1111/j.1469-7793.2001.0341a.x
https://doi.org/10.1111/j.1469-7793.2001.0341a.x
Autor:
Burton Horowitz, Philip Doherty, James L. Kenyon, A. Carl, William J. Hatton, Mark J. Latten, Kenton M. Sanders, Helen S. Mason
Publikováno v:
The Journal of Physiology. 533:315-327
1. Located within the gastrointestinal (GI) musculature are networks of cells known as interstitial cells of Cajal (ICC). ICC are associated with several functions including pacemaker activity that generates electrical slow waves and neurotransmissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997d0d4048314953ac86dd766ad43c36
https://doi.org/10.1111/j.1469-7793.2001.0315a.x
https://doi.org/10.1111/j.1469-7793.2001.0315a.x
Publikováno v:
Life Sciences. 68:1585-1591
Some drugs acting on 5-hydroxytryptamine receptors inhibit the rapid component of delayed rectifying potassium currents (I(Kr)) in cardiac muscle cells. This is associated with lengthening of the QT interval in the cardiac cycle and can lead to fatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::179edba2e5b0e281d94091be6a222e3a
https://doi.org/10.1016/s0024-3205(01)00947-x
https://doi.org/10.1016/s0024-3205(01)00947-x
Autor:
James L. Kenyon
Publikováno v:
Neuroscience Letters. 296:9-12
In order to establish the physiological role of the Ca(2+)-activated Cl(-) current (I(Cl(Ca))) of chick primary afferent neurons, I measured the reversal potential of this current using either the amphotericin perforated patch technique (that alters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20836819db5e12a4c3bf2b76d0b5530d
https://doi.org/10.1016/s0304-3940(00)01610-4
https://doi.org/10.1016/s0304-3940(00)01610-4
Autor:
James L. Kenyon, R.J Bauer
Publikováno v:
Journal of Neuroscience Methods. 96:105-111
We investigated the ability of amplitude distributions to determine if the gating of a pair of channels is coupled. These distributions are expressed as probability density amplitude histograms with peaks corresponding to zero, one, or two open chann
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b039b3ac090dbc50b5280f9051ca49
https://doi.org/10.1016/s0165-0270(99)00189-2
https://doi.org/10.1016/s0165-0270(99)00189-2