Zobrazeno 1 - 7
of 7
pro vyhledávání: '"James L. Ivett"'
Autor:
Sheila M. Galloway, James L. Ivett, Marilyn J. Aardema, Takeshi Morita, Motoi Ishidate, David Kirkland, Pasquale Mosesso, Toshio Sofuni
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 312:241-261
The following summary represents a consensus of the working group except where noted. The items discussed are listed in the order in which they appear in the OECD guideline (473) for easy reference. Metabolic activation. S9 from animals induced eithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b49c389293eb925fe7aa2f1d3783e0b
https://doi.org/10.1016/0165-1161(94)00012-3
https://doi.org/10.1016/0165-1161(94)00012-3
Publikováno v:
Mutation Research/Genetic Toxicology. 298:43-51
Concentrated organic residues extracted from 5 blended aliquots of commercial beers were evaluated for their ability to induce sister chromatid exchange (SCE), chromosomal aberrations and forward mutation in Chinese hamster ovary (CHO) cells. Each ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15c30e3c729b8cf8d20d81ad6e8a2a7
https://doi.org/10.1016/0165-1218(92)90027-w
https://doi.org/10.1016/0165-1218(92)90027-w
Autor:
James L Ivett, B Jessen, Bhasker Shetty, C C Capen, T E Ryan, R Gasser, Gregory J. Stevens, J C Theiss, Leigh Ann Burns-Naas, R M McClain, G Furman, W Evering, Mark Zorbas, E Wu, J C Cook, Stephanie Webber, M Chen
Publikováno v:
Humanexperimental toxicology. 24(12)
The carcinogenic potential of nelfinavir mesylate (nelfinavir) was evaluated in a 2-year oral (gavage) study on Sprague-Dawley rats at dose levels of 0 (control), 0 (vehicle control), 100, 300 and 1000 mg/kg per day. At the end of the treatment, incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26c16a3607fe5464da333fc5d34f14b
https://pubmed.ncbi.nlm.nih.gov/16408618
https://pubmed.ncbi.nlm.nih.gov/16408618
Autor:
Leigh Ann Burns-Naas, J. Ann McCay, Mark Zorbas, Kimber L. White, James L Ivett, Stephanie Webber
Publikováno v:
Humanexperimental toxicology. 24(2)
The objective of these investigations was to determine whether exposure to the HIV-1 protease inhibitor nelfinavir compromises immune function in Sprague Dawley rats. Animals (20/sex per group) were exposed orally for 1 or 6 months to nelfinavir at d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28ac04d3902f0572db87c411a4f4023
https://pubmed.ncbi.nlm.nih.gov/15850281
https://pubmed.ncbi.nlm.nih.gov/15850281
Autor:
Helen C. Cunny, James L Ivett, Jeffrey M. Charles, B. Bhaskar Gollapudi, Ronald D. Wilson, Hema Murli, James S. Bus
Publikováno v:
Mutation research. 444(1)
The potential for 2,4-D and seven of its salts and esters to induce cytogenetic abnormalities in mammalian cells in vivo was investigated in the mouse bone marrow micronucleus test. All the test materials were administered to male and female mice by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29a7aac33072e83870fcb6deecec4c6
https://pubmed.ncbi.nlm.nih.gov/10477358
https://pubmed.ncbi.nlm.nih.gov/10477358
Autor:
Robert W. Kapp, Lawrence W. Masten, T. H. Gardiner, Richard H. McKee, James L. Ivett, Robert R. Young, Dale J. Marino, T. R. Tyler
Publikováno v:
Environmental and molecular mutagenesis. 22(2)
To assess the mutagenic potential of isopropanol, an in vitro Chinese hamster ovary (CHO) cell/HGPRT gene mutation assay and a bone marrow micronucleus study in mice were conducted. In the CHO/HGPRT assay, concentration levels ranged from 0.5 to 5.0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f87d437f4df71e44f382e1b96391bb5
https://pubmed.ncbi.nlm.nih.gov/8359158
https://pubmed.ncbi.nlm.nih.gov/8359158
Autor:
Hemalatha Murli, James L. Ivett, John J. Mulvihill, Sherri J. Bale, Dilys M. Parry, Allen E. Bale
Publikováno v:
Cancer Genetics and Cytogenetics. 42:273-279
Previous studies of chromosome stability in the nevoid basal cell carcinoma syndrome have yielded inconsistent results and suffered from small sample sizes and less than optimal controls. We investigated chromosome fragility and sister chromatid exch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac19bc812b8d25eaa79d83f7c06e8650
https://doi.org/10.1016/0165-4608(89)90095-2
https://doi.org/10.1016/0165-4608(89)90095-2