Zobrazeno 1 - 10
of 180
pro vyhledávání: '"James L. Gleason"'
Autor:
Camille Barbier, Ali Mansour, Aiten Ismailova, Fatemeh Sarmadi, David A. Scarlata, Manuella Bouttier, Camille Zeitouni, Catherine Wang, James L. Gleason, John H. White
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25D), and its analogues signal through the nuclear vitamin D receptor (VDR), a ligand-regulated transcription factor, and have been extensively investigated as anticancer agents. 1,25D
Externí odkaz:
https://doaj.org/article/8e5febe9a7fc41268166f1bbb0aaa9e7
Publikováno v:
Organic Letters. 25:777-781
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c48669b5b0d425aec44a6353f9c1f7f
https://doi.org/10.1021/acs.orglett.2c04269
https://doi.org/10.1021/acs.orglett.2c04269
Autor:
James L. Gleason, Josephine M. Warnica
Publikováno v:
Canadian Journal of Chemistry. 100:212-216
A cyclic hydrazide catalyst bearing a pendant anthracene catalyzes the polyene cyclization of 1,5-hexadiene-2-carboxaldehydes. Bicyclic closure proceeds in substrates with non-activated terminating groups that fail to react with simple hydrazide cata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edb9f3517eeebe68e8fed9a5ad612f1d
https://doi.org/10.1139/cjc-2021-0150
https://doi.org/10.1139/cjc-2021-0150
Autor:
Anthony R. Izzotti, James L. Gleason
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(49)
The cycloaddition of heptafulvalene (1) with tetracyanoethylene (TCNE) was previously described as an example of an antarafacial cycloaddition, a [π
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ebe61bf8572b7770a3b96d17f98cfc
https://pubmed.ncbi.nlm.nih.gov/35671245
https://pubmed.ncbi.nlm.nih.gov/35671245
Autor:
Samuel J. Plamondon, James L. Gleason
Publikováno v:
Organic letters. 24(12)
The first total synthesis of the abietaquinone methide diterpenoid (-)-3-oxoisotaxodione is reported. The key enabling step is the use of a chiral bicyclic hydrazide as an organocatalyst for the enantioselective polyene cyclization of a (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e63a7cf6f93568df34c8811f223b52
https://pubmed.ncbi.nlm.nih.gov/35311261
https://pubmed.ncbi.nlm.nih.gov/35311261
Publikováno v:
Journal of the American Chemical Society. 142:16877-16886
The mechanism of the organocatalytic Cope rearrangement is elucidated through a combined computational and experimental approach. As reported previously, hydrazides catalyze the Cope rearrangement of 1,5-hexadiene-2-carboxaldehydes via iminium ion fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38afc29fe7e9ac63d381afb3e76e4624
https://doi.org/10.1021/jacs.0c08427
https://doi.org/10.1021/jacs.0c08427
Autor:
Kyle F. Biegasiewicz, Michelle L. Ingalsbe, Jeffrey D. St. Denis, James L. Gleason, Junming Ho, Michelle L. Coote, G. Paul Savage, Ronny Priefer
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 1814-1818 (2012)
Recently, a novel chiral cubane-based Schiff base ligand was reported to yield modest enantioselectivity in the Henry reaction. To further explore the utility of this ligand in other asymmetric organic transformations, we evaluated its stereoselectiv
Externí odkaz:
https://doaj.org/article/8359bd1cc5e6480bbd01fb670fbc4d17
Autor:
Adam A. H. Elmehriki, James L. Gleason
Publikováno v:
Organic Letters. 21:9729-9733
Cyclic α-quaternary carbon stereocenters were prepared from biselectrophillic substrates and an easily prepared chiral bicyclic sulfonyl lactam. This was achieved in two steps by spiroalkylation, e...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10b7990d54c610d41439331760bacef4
https://doi.org/10.1021/acs.orglett.9b03887
https://doi.org/10.1021/acs.orglett.9b03887
Autor:
David Cotnoir-White, Ryan R.G. Barrett, Axel A. Thomson, Sylvie Mader, James L. Gleason, Marine Diennet, Claire Nash, Christopher Doyle
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 55:128441
The combination of androgen receptor antagonists with histone deacetylase inhibitors (HDACi) has been shown to be more effective than antiandrogens alone in halting growth of prostate cancer cell lines. Here we have designed, synthesized and assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b905996f6789c62644b4424906836aa6
https://doi.org/10.1016/j.bmcl.2021.128441
https://doi.org/10.1016/j.bmcl.2021.128441
Publikováno v:
European Journal of Organic Chemistry. 2018:5412-5416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0acd49e1ceed585e9d26a7199f4c5700
https://doi.org/10.1002/ejoc.201801009
https://doi.org/10.1002/ejoc.201801009