Zobrazeno 1 - 10
of 66
pro vyhledávání: '"James L. Gamble"'
Autor:
James L. Gamble
Publikováno v:
Nutrition Reviews. 47:199-201
Editor's Note : James Gamble's Harvey Lecture of 1947 described experiments that provided the foundation for modern understanding of the physiology of fluid and electrolyte balance during deprivation. The excerpt here reports Gamble's elegantly clear
Contraction-induced Changes in Acetyl-CoA Carboxylase and 5′-AMP-activated Kinase in Skeletal Muscle
Autor:
Abhay Patel, Asish K. Saha, Bruce E. Kemp, Neil B. Ruderman, Lee A. Witters, James L. Gamble, Demetrios G. Vavvas, Alexios Apazidis
Publikováno v:
Journal of Biological Chemistry. 272:13255-13261
The concentration of malonyl-CoA, a negative regulator of fatty acid oxidation, diminishes acutely in contracting skeletal muscle. To determine how this occurs, the activity and properties of acetyl-CoA carboxylase beta (ACC-beta), the skeletal muscl
Autor:
James L. Gamble
Publikováno v:
Perspectives in Biology and Medicine. 39:593-600
Publikováno v:
The Journal of Experimental Medicine
From the data given above the following explanation of the effects of continued loss of the external secretion of the pancreas may be offered. The underlying event is a steadily increasing deficit of sodium and of chloride ion due to the large requir
Publikováno v:
The Journal of Experimental Medicine
The circumstances present in upper intestinal obstruction which may be expected to reduce the water content of the body are fasting with water deprivation and a continued loss of secretions into the stomach. According to the data obtained from the ab
Publikováno v:
The Journal of biological chemistry. 273(52)
The AMP-activated protein kinase is a heterotrimeric enzyme, important in cellular adaptation to the stress of nutrient starvation, hypoxia, increased ATP utilization, or heat shock. This mammalian enzyme is composed of a catalytic alpha subunit and
Autor:
James L. Gamble, Bruce E. Kemp, Christina Ullrich, Lee A. Witters, David Stapleton, Ken I. Mitchelhill, Belinda J. Michell, Colin M. House, Jason R. B. Dyck
Publikováno v:
The Journal of biological chemistry. 272(39)
The AMP-activated protein kinase (AMPK) consists of catalytic alpha and noncatalytic beta and gamma subunits and is responsible for acting as a metabolic sensor for AMP levels. There are multiple genes for each subunit and the rat liver AMPK alpha1 a
Autor:
James L. Gamble
Publikováno v:
Advances in Physiology Education. 277:S136
Buffering of "metabolic" acid in tissues other than blood correlates closely with a change in extracellular bicarbonate concentration rather than with a change in extracellular pH. Of particular importance is the evidence for an absence of relation t
Autor:
James L. Gamble
Publikováno v:
Atlantic Economic Journal. 25:323-323
Autor:
Anne M. Skoff, James L. Gamble
Publikováno v:
Kidney and Blood Pressure Research. 5:157-164
Total CO2 (CO2+HCO-3) was measured in alkaline extracts of quickly frozen rat renal cortex. The mean concentration calculated for tissue water was 18.7 ± SD 1.6 mEq/1 (n=10) when that measured in plasma water was 23.5 ± 1.7. In other experiments (n