Zobrazeno 1 - 10
of 92
pro vyhledávání: '"James L. Funderburgh"'
Autor:
Rachelle N. Palchesko, Yiqin Du, Moira L. Geary, Santiago Carrasquilla, Daniel J. Shiwarski, Irona Khandaker, James L. Funderburgh, Adam W. Feinberg
Publikováno v:
Communications Materials, Vol 3, Iss 1, Pp 1-12 (2022)
Tissue regeneration by injecting cells into the damaged area is a common clinical treatment, but is not always affective. Here, a shrink-wrap-like process is reported for corneal endothelial cells, allowing them to be engrafted into the corneal endot
Externí odkaz:
https://doaj.org/article/8ab9287d7ba348aa80f938cc7888d58b
Autor:
Lin Weng, James L. Funderburgh, Irona Khandaker, Moira L. Geary, Tianbing Yang, Rohan Basu, Martha L. Funderburgh, Yiqin Du, Gary Hin-Fai Yam
Publikováno v:
Eye and Vision, Vol 7, Iss 1, Pp 1-14 (2020)
Abstract Background Corneal stromal stem cells (CSSC) reduce corneal inflammation, prevent fibrotic scarring, and regenerate transparent stromal tissue in injured corneas. These effects rely on factors produced by CSSC to block the fibrotic gene expr
Externí odkaz:
https://doaj.org/article/38dd86384fa54355b7323c3fe6d277c2
Autor:
Golnar Shojaati, Irona Khandaker, Martha L. Funderburgh, Mary M. Mann, Rohan Basu, Donna B. Stolz, Moira L. Geary, Aurélie Dos Santos, Sophie X. Deng, James L. Funderburgh
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 11, Pp 1192-1201 (2019)
Abstract Mesenchymal stem cells from corneal stromal stem cells (CSSC) prevent fibrotic scarring and stimulate regeneration of transparent stromal tissue after corneal wounding in mice. These effects rely on the ability of CSSC to block neutrophil in
Externí odkaz:
https://doaj.org/article/acbdd15b352b43dd8c003f9f202aca2a
Autor:
James L. Funderburgh, Sujatha Prakash
Publikováno v:
BioTechniques, Vol 20, Iss 3, Pp 376-378 (1996)
Externí odkaz:
https://doaj.org/article/d18ff09675cd4c19936ebb78b0a69ff9
Autor:
Gary Hin-Fai Yam, Tianbing Yang, Moira L Geary, Mithun Santra, Martha Funderburgh, Elizabeth Rubin, Yiqin Du, Jose A Sahel, Vishal Jhanji, James L Funderburgh
Publikováno v:
Journal of Advanced Research, Vol 45, Iss , Pp 141-155 (2023)
Introduction: Corneal blindness due to scarring is treated with corneal transplantation. However, a global problem is the donor material shortage. Preclinical and clinical studies have shown that cell-based therapy using corneal stromal stem cells (C
Externí odkaz:
https://doaj.org/article/5b9861b24c7f4e1385e9d790328a6fb3
Autor:
Carrasquilla S, Yiqin Du, James L. Funderburgh, Rachelle N. Palchesko, Adam W. Feinberg, Irona Khandaker, Moira L. Geary, Daniel J. Shiwarski
Cell injection has emerged as a widespread approach for therapeutic delivery of healthy cells into diseased and damaged tissues to achieve regeneration. However, cell retention, viability and integration at the injection site has generally been poor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c41bc749d9afc4ea75246c1b83a33dd0
https://doi.org/10.1101/2021.03.01.433476
https://doi.org/10.1101/2021.03.01.433476
Autor:
Rohan Basu, Martha L. Funderburgh, Moira L. Geary, Yiqin Du, Lin Weng, Gary Hin-Fai Yam, James L. Funderburgh, Tianbing Yang, Irona Khandaker
Publikováno v:
Eye and Vision
Eye and Vision, Vol 7, Iss 1, Pp 1-14 (2020)
Eye and Vision, Vol 7, Iss 1, Pp 1-14 (2020)
Background Corneal stromal stem cells (CSSC) reduce corneal inflammation, prevent fibrotic scarring, and regenerate transparent stromal tissue in injured corneas. These effects rely on factors produced by CSSC to block the fibrotic gene expression. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f97350e0dcb200baf401585aa01d89c
https://doi.org/10.1186/s40662-020-00217-z
https://doi.org/10.1186/s40662-020-00217-z
Autor:
Martha L. Funderburgh, Gary Hin-Fai Yam, Irona Khandaker, Yiqin Du, James L. Funderburgh, Vishal Jhanji, Moira L. Geary
Publikováno v:
Exp Eye Res
Corneal opacities affect vision for millions of individuals worldwide. Fibrotic scar tissues accumulate in reaction to inflammatory responses and remain permanently in corneal stroma, and conventionally correctable only by donor corneal transplantati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98231f2dd63e3b786b9e7a5f13bba76
https://pubmed.ncbi.nlm.nih.gov/32979396
https://pubmed.ncbi.nlm.nih.gov/32979396
Autor:
Irona Khandaker, James L. Funderburgh, Kyle Sylakowski, Yiqin Du, Martha L. Funderburgh, Golnar Shojaati
Publikováno v:
Stem Cells Translational Medicine
Stem cells from human corneal stroma (CSSC) suppress corneal stromal scarring in a mouse wound-healing model and promote regeneration of native transparent tissue (PMID:25504883). This study investigated efficacy of compressed collagen gel (CCG) as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46ceff0bb59d6ced892c0ee869f5730
https://doi.org/10.1002/sctm.17-0258
https://doi.org/10.1002/sctm.17-0258
Autor:
Rachelle N. Palchesko, Adam W. Feinberg, Martha L. Funderburgh, Fatima N. Syed-Picard, Andrew Hertsenberg, James L. Funderburgh, Yiqin Du
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 12:59-69
Blinding corneal scarring is predominately treated with allogeneic graft tissue; however, there is a worldwide shortage of donor tissue leaving millions in need of therapy. Human corneal stromal stem cells (CSSC) have been shown produce corneal tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfa3a8d7d8f8f9d98896c88346123676
https://doi.org/10.1002/term.2363
https://doi.org/10.1002/term.2363