Zobrazeno 1 - 10
of 72
pro vyhledávání: '"James L. Burchette"'
Publikováno v:
Rare Tumors, Vol 2 (2010)
Tumors of the matrix of rigid structures include matrical tumors of the hairs, nails, and teeth. These tumors share similar phenotypical and signaling features. Although benign matrical hair tumors are among the most common of these tumors, hair matr
Externí odkaz:
https://doaj.org/article/2d9e720ffa4e4c33931807600170f4c8
Publikováno v:
Hepatology. 61:98-107
Hedgehog (Hh) ligand production by ballooned hepatocytes drives nonalcoholic steatohepatitis (NASH) progression in mice. The NIDDK-sponsored PIVENS trial (NCT00063622) showed that vitamin E (VitE) improved NASH. We investigated whether VitE treatment
Autor:
David Boczkowski, Smita K. Nair, Nancy Pickett, N. Rebecca Haley, Douglas S. Tyler, Duane Mitchell, Gary E. Archer, Mark Harper, Paul J. Mosca, James L. Burchette, Scott K. Pruitt, John H. Sampson, Nicole de Rosa, Jens Dannull, Maria Angelica Selim
Publikováno v:
Journal of Clinical Investigation. 123:3135-3145
Background. Many cancers, including melanoma, exclusively express constitutive proteasomes (cPs) and are unable to express immunoproteasomes (iPs). In contrast, mature DCs used for immunotherapy exclusively express iPs. Since proteasomes generate pep
Publikováno v:
The American Journal of Dermatopathology. 35:458-462
IgG4-related disease is a syndrome which involves lymphoplasmacytic infiltrates and soft tissue sclerosis, elevated serum IgG4 titer, and increased IgG4-positive plasma cells in a variety of tissues. Scleroderma is also characterized by fibrosis and
Autor:
Jerald Z. Gong, Christopher L. Alley, Cherie H. Dunphy, Endi Wang, Elizabeth L. Boswell, Chuanyi M. Lu, James L. Burchette, Anand S. Lagoo
Publikováno v:
Archives of Pathology & Laboratory Medicine. 137:503-517
Context.—Plasma cell myeloma and chronic lymphocytic leukemia are both common hematologic malignancies, sharing many epidemiologic features. Concomitant detection of the 2 conditions poses special diagnostic challenges for the pathologist. Objectiv
Autor:
Mario Gonzalez-Gronow, Gustaaf G. de Ridder, Maria Angelica Selim, Lihong Mo, James L. Burchette, Salvatore V. Pizzo, Edith V. Bowers
Publikováno v:
Melanoma Research. 21:323-334
A correlation between expression of the glucose-regulated protein of 78 kDa (GRP78) in malignant melanoma tumors and poor patient survival is well established. In this study, in addition to demonstrating the expression of GRP78 in tumor tissue, we in
Autor:
Zuowei Su, Antonio García de Herreros, Gloria Broadwater, Joseph Geradts, James L. Burchette, Robin E. Bachelder
Publikováno v:
Human Pathology. 42:1125-1131
Snail1 and ZEB1 are transcriptional repressors that drive tumor initiation and metastasis in animal models. Snail1 and ZEB1 are frequently coexpressed in tumor cell lines, suggesting that these factors may cooperate to promote tumor progression. Howe
Autor:
Wei Chen, Cynthia D. Guy, Ayako Suzuki, Jiuyi Lu, Anna Mae Diehl, Fatima A. Rangwala, Manal F. Abdelmalek, James L. Burchette
Publikováno v:
The Journal of Pathology. 224:401-410
Ballooned hepatocytes distinguish non-alcoholic steatohepatitis (NASH) from steatosis. Such cells contain dilated endoplasmic reticulum and ubiquitin aggregates, characteristics of endoplasmic reticulum stress. Hepatocyte ballooning increases the ris
Autor:
Christina K. Augustine, M. Angelica Selim, Nicole McMahon, Sin-Ho Jung, James C. Padussis, James L. Burchette, Scott K. Pruitt, Jin S. Yoo, Hiroaki Toshimitsu, Georgia M. Beasley, Patricia A. Zipfel, Francis Ali-Osman, Douglas S. Tyler, Yasunori Yoshimoto
Publikováno v:
Molecular Cancer Therapeutics. 9:2090-2101
Melanoma responds poorly to standard chemotherapy due to its intrinsic chemoresistance. Multiple genetic and molecular defects, including an activating mutation in the BRaf kinase gene, are associated with melanoma, and the resulting alterations in s
Autor:
Krystal B. Johnson, Mario Gonzalez-Gronow, James L. Burchette, Salvatore V. Pizzo, John A. Papalas, Kenneth E. Youens, Robin T. Vollmer, Maria Angelica Selim
Publikováno v:
Modern Pathology. 23:134-143
Cell surface expression of glucose-regulated protein 78 (GRP78) occurs in several types of cancer; however, its role in the behavior of primary cutaneous melanoma is not well studied. The association of cell surface GRP78 with other proteins such as