Zobrazeno 1 - 10
of 12
pro vyhledávání: '"James L. Bloss"'
Autor:
James L. Bloss, Donna L. Hammond
Publikováno v:
European journal of pharmacology. 231(2)
This study evaluated the antinociceptive activity of an opioid dipeptide arylalkylamide, SC-39566 (2,6-dimethyl-L-tyrosinyl-D-alanyl-(3-phenyl-1-propyl)-amide), in the Rhesus monkey using the discrete trial, intermittent shock titration paradigm. I.m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe8629be1d7e6d17888d96837912abb
https://pubmed.ncbi.nlm.nih.gov/8095901
https://pubmed.ncbi.nlm.nih.gov/8095901
Autor:
Robert J. Chorvat, James D. Hirsch, Suzanne Evans Radak, James L. Bloss, Stanley S. Tenen, Bipin N. Desai
Publikováno v:
Journal of Medicinal Chemistry. 26:845-850
A series of oxopyridobenzothiazines (azaphenothiazines) were prepared and evaluated for binding to the benzodiazepine receptor, anticonvulsant activity in the pentylenetetrazole-induced convulsion assay, and, in two cases, ability to increase punishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65702037fa73874c9c5da87829709518
https://doi.org/10.1021/jm00360a011
https://doi.org/10.1021/jm00360a011
Autor:
James L. Bloss, Garry H. Singer
Publikováno v:
Psychopharmacology. 57:295-302
Prostaglandin E2 (PGE2) and 11-thiol-11-desoxy Prostaglandin E2 (SHPGE2) were evaluated in a variety of behavioral and neuropharmacological procedures that are sensitive to neuroleptics. Clozapine (C), thioridazine (T), haloperidol (H), and fluphenaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b65f42b07aa7c4a3092fe43a5a838f
https://doi.org/10.1007/bf00426754
https://doi.org/10.1007/bf00426754
Autor:
James L. Bloss, Dilip R. Sanvordeker
Publikováno v:
Journal of Pharmaceutical Sciences. 66:82-85
The effect of several lipid and nonlipid pharmaceutical solvents on the in vivo activity of 1‐diphenylmethyl‐4‐[(6‐methyl‐2‐pyridyl)methyleneamino]piperazine (I) was evaluated in the mouse. The intensity of onset and the duration of antic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3103c352d81a246bf3308f876e146aa
https://doi.org/10.1002/jps.2600660120
https://doi.org/10.1002/jps.2600660120
Autor:
James L. Bloss, S. E. Radak, Bipinchandra Nanubhai Desai, Robert J. Chorvat, Stanley S. Tenen, J. Hirsch
Publikováno v:
Chemischer Informationsdienst. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef99c590be7c6230392f6ee1ae5db37
https://doi.org/10.1002/chin.198408210
https://doi.org/10.1002/chin.198408210
Publikováno v:
Chemischer Informationsdienst. 10
A number of molecular similarities between the antipsychotic agents butaclamol and clozapine were noted. Based on the premise that this was a strong indicator of a common mechanism of action (i.e., binding at the antagonist state of the dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::294ff7cc6098f5a747e9c7509f50155c
https://doi.org/10.1002/chin.197934225
https://doi.org/10.1002/chin.197934225
Autor:
James L. Bloss, Donna L. Hammond
Publikováno v:
Brain research. 499(2)
This study addressed issues concerning the validity of the shock titration paradigm by using focal, pulsed electrocutaneous stimulation and including unavoidable suprathreshold intensity stimuli among titratable, threshold intensity trials. In saline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56e3ff6c0cfdf307c50ff456a3e88b6
https://pubmed.ncbi.nlm.nih.gov/2804681
https://pubmed.ncbi.nlm.nih.gov/2804681
Publikováno v:
Journal of medicinal chemistry. 22(4)
A number of molecular similarities between the antipsychotic agents butaclamol and clozapine were noted. Based on the premise that this was a strong indicator of a common mechanism of action (i.e., binding at the antagonist state of the dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7252027e3a172b5f7d75408e66339808
https://pubmed.ncbi.nlm.nih.gov/34721
https://pubmed.ncbi.nlm.nih.gov/34721
Publikováno v:
Journal of medicinal chemistry. 20(11)
A series of beta-spiro[pyrrolidinoindolines], 3a-d, was prepared and evaluated for their ability to bind to the glycine receptor. These compounds were also tested in vivo to determine if they would produce convulsant or anxiolytic effects. The target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3850b54babc7f609dd89dcbdc72dc914
https://pubmed.ncbi.nlm.nih.gov/199727
https://pubmed.ncbi.nlm.nih.gov/199727
Publikováno v:
Pain. 30:S253
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e62b1890eacd4766cc1a045d561423d
https://doi.org/10.1016/0304-3959(87)91567-3
https://doi.org/10.1016/0304-3959(87)91567-3