Zobrazeno 1 - 6
of 6
pro vyhledávání: '"James L Shepherdson"'
Autor:
Dana M King, Clarice Kit Yee Hong, James L Shepherdson, David M Granas, Brett B Maricque, Barak A Cohen
Publikováno v:
eLife, Vol 9 (2020)
In embryonic stem cells (ESCs), a core transcription factor (TF) network establishes the gene expression program necessary for pluripotency. To address how interactions between four key TFs contribute to cis-regulation in mouse ESCs, we assayed two m
Externí odkaz:
https://doaj.org/article/f9675b0408cc4d5b9a53f8a0915f9a84
Autor:
James L. Shepherdson, Ryan Z. Friedman, Yiqiao Zheng, Chi Sun, Inez Y. Oh, David M. Granas, Barak A. Cohen, Shiming Chen, Michael A. White
Publikováno v:
bioRxiv
Dozens of variants in the photoreceptor-specific transcription factor (TF) CRX are linked with different human blinding diseases that vary in their severity and age of onset. How different variants in a single TF cause a range of pathological phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f849484d39c188dd4caee3b346c53c3
https://europepmc.org/articles/PMC10245955/
https://europepmc.org/articles/PMC10245955/
Publikováno v:
Bone
Microdeletions within 1q24 have been associated with growth deficiency, varying intellectual disability, and skeletal abnormalities. The candidate locus responsible for the various phenotypic features of this syndrome has previously been predicted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79861f8a1a084d35b2e4ebb9bc0048e3
https://pubmed.ncbi.nlm.nih.gov/33141070
https://pubmed.ncbi.nlm.nih.gov/33141070
Autor:
Brett B Maricque, Clarice Kit Yee Hong, James L Shepherdson, Dana M King, Barak A. Cohen, David M Granas
Publikováno v:
eLife, Vol 9 (2020)
Transcription factors are proteins that flip genetic switches; their role is to control when and where genes are active. They do this by binding to short stretches of DNA called cis-regulatory sequences. Each sequence can have several binding sites f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a62a3639b4c2c02037a0291d1c60fd
https://elifesciences.org/articles/41279
https://elifesciences.org/articles/41279
Autor:
Dana M, King, Clarice Kit Yee, Hong, James L, Shepherdson, David M, Granas, Brett B, Maricque, Barak A, Cohen
Publikováno v:
eLife
In embryonic stem cells (ESCs), a core transcription factor (TF) network establishes the gene expression program necessary for pluripotency. To address how interactions between four key TFs contribute to cis-regulation in mouse ESCs, we assayed two m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93d49ee2ecc403767dfef72df0001844
https://pubmed.ncbi.nlm.nih.gov/32043966
https://pubmed.ncbi.nlm.nih.gov/32043966