Zobrazeno 1 - 10
of 12
pro vyhledávání: '"James L Holloway"'
Autor:
Dirk Schadendorf, Ignacio Melero, Robert L Ferris, William Sharfman, Satyendra Suryawanshi, Jaclyn Neely, Fabrice Barlesi, Dung T Le, Jason J Luke, Patrick A Ott, Tina Cascone, Nikhil I Khushalani, Abanti Sanyal, Scott Ely, Manish R Sharma, Deanne Lathers, James L Holloway, Rasika Suryawanshi, Neil H Segal
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 3 (2024)
Background Resistance to immune checkpoint inhibitors and targeted treatments for cancer is common; thus, novel immunotherapy agents are needed. Urelumab is a monoclonal antibody agonist that binds to CD137 receptors expressed on T cells. Here, we re
Externí odkaz:
https://doaj.org/article/6310bf50e26a495fafc831096d8929f8
Autor:
Nathan O Siemers, James L Holloway, Han Chang, Scott D Chasalow, Petra B Ross-MacDonald, Charles F Voliva, Joseph D Szustakowski
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179726 (2017)
Therapeutic options for the treatment of an increasing variety of cancers have been expanded by the introduction of a new class of drugs, commonly referred to as checkpoint blocking agents, that target the host immune system to positively modulate an
Externí odkaz:
https://doaj.org/article/97ededee36164e1f82e0b2082605a781
Autor:
Namit Kumar, Ryan Golhar, Kriti Sen Sharma, James L. Holloway, Srikant Sarangi, Isaac Neuhaus, Alice M. Walsh, Zachary W. Pitluk
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Single-cell (sc) sequencing performs unbiased profiling of individual cells and enables evaluation of less prevalent cellular populations, often missed using bulk sequencing. However, the scale and the complexity of the sc dataset
Externí odkaz:
https://doaj.org/article/c3a9fdd3833a4acebbf9e4411caff6e7
Autor:
Peter M. Szabo, Amir Vajdi, Namit Kumar, Michael Y. Tolstorukov, Benjamin J. Chen, Robin Edwards, Keith L. Ligon, Scott D. Chasalow, Kin-Hoe Chow, Aniket Shetty, Mohan Bolisetty, James L. Holloway, Ryan Golhar, Brian A. Kidd, Philip Ansumana Hull, Jeff Houser, Logan Vlach, Nathan O. Siemers, Saurabh Saha
Publikováno v:
Scientific Reports. 13
Epithelial-to-mesenchymal transition (EMT) is associated with tumor initiation, metastasis, and drug resistance. However, the mechanisms underlying these associations are largely unknown. We studied several tumor types to identify the source of EMT g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3f11e56e50ac94feeb55c89610ebe87
https://doi.org/10.1038/s41598-023-28480-9
https://doi.org/10.1038/s41598-023-28480-9
Autor:
Isaac M. Neuhaus, Namit Kumar, Kriti Sen Sharma, Alice M. Walsh, Zachary W. Pitluk, Ryan Golhar, James L. Holloway, Srikant Sarangi
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
BMC Genomics
BMC Genomics
Background Single-cell (sc) sequencing performs unbiased profiling of individual cells and enables evaluation of less prevalent cellular populations, often missed using bulk sequencing. However, the scale and the complexity of the sc datasets poses a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a963927228e6278260524e6f026cd6ff
https://doi.org/10.1186/s12864-020-07300-8
https://doi.org/10.1186/s12864-020-07300-8
Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors
Autor:
Charles F. Voliva, James L. Holloway, Scott D. Chasalow, Han Chang, Nathan O. Siemers, Petra Ross-Macdonald, Joseph D. Szustakowski
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179726 (2017)
PLoS ONE
PLoS ONE
Therapeutic options for the treatment of an increasing variety of cancers have been expanded by the introduction of a new class of drugs, commonly referred to as checkpoint blocking agents, that target the host immune system to positively modulate an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0187df20375a3dec7bee7e9333c037
http://europepmc.org/articles/PMC5531551?pdf=render
http://europepmc.org/articles/PMC5531551?pdf=render
Autor:
Russell J. Rodriguez, David R. Clifton, James L. Holloway, Carl O. Ostberg, Charlotte Rasmussen
Publikováno v:
Transactions of the American Fisheries Society. 132:131-142
A marker based on randomly amplified polymorphic DNA (RAPD), OT-38, was discovered that nonlethally discriminates between stream-type and ocean-type populations of chinook salmon Oncorhynchus tshawytscha in the Columbia River basin, including the thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca8b6b7b6b5fb93c3742b4e76198b4d4
https://doi.org/10.1577/1548-8659(2003)132<0131:ioagmt>2.0.co
https://doi.org/10.1577/1548-8659(2003)132<0131:ioagmt>2.0.co
Autor:
Mark F. Maurer, James L. Holloway, Andrew L. Feldhaus, Kimberly E. Shoemaker, Theodore E. Whitmore
Publikováno v:
Gene. 245:103-108
The cystatin superfamily of cysteine proteinase inhibitors consists of three major families. In the present study, we report the cloning of the cDNA for mouse cystatin T, which is related to family 2 cystatins. The deduced amino acid sequence of cyst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dd411aa980d5db44af19e6990eb5c8
https://doi.org/10.1016/s0378-1119(00)00030-5
https://doi.org/10.1016/s0378-1119(00)00030-5
Autor:
Shannon L. Okada, Harald S. Haugen, Jeff L. Ellsworth, Paul O. Sheppard, Anitra Wolf, James L. Holloway, Diane M. Durnam, Kimberly S. Waggie, Harold Storey, Merideth L. Kelley, Lena Y. Yao, Philippa J. Webster, Hong-Ping Ren, Katherine E. Lewis
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 20(2)
Corticotroph-derived glycoprotein hormone (CGH), also referred to as thyrostimulin, is a noncovalent heterodimer of glycoprotein hormone alpha 2 (GPHA2) and glycoprotein hormone beta 5 (GPHB5). Here, we demonstrate that both subunits of CGH are expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a908fef1baa0d318d6ef5efa4efc31d4
https://pubmed.ncbi.nlm.nih.gov/16210345
https://pubmed.ncbi.nlm.nih.gov/16210345
Autor:
Joel L. Weissfeld, James L. Holloway
Publikováno v:
Archives of Internal Medicine. 151:973
A randomized clinical trial assessed the effectiveness of control, low-intensity, and high-intensity stop-smoking treatments in a Department of Veterans Affairs outpatient setting. The study actively recruited male cigarette smokers attending outpati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa40c8411345e3959a0706476d90a740
https://doi.org/10.1001/archinte.1991.00400050117022
https://doi.org/10.1001/archinte.1991.00400050117022