Zobrazeno 1 - 10
of 18
pro vyhledávání: '"James Kozubek"'
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease that lacks known pathogenesis, distinctive diagnostic criteria, and effective treatment options. Understanding the genetic (and other) r
Externí odkaz:
https://doaj.org/article/ea8a2d1b08fe432b814498ef05112b82
Autor:
James Kozubek, Zhihai Ma, Elizabeth Fleming, Tatiana Duggan, Rong Wu, Dong-Guk Shin, Soheil S Dadras
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72699 (2013)
The full repertoire of human microRNAs (miRNAs) that could distinguish common (benign) nevi from cutaneous (malignant) melanomas remains to be established. In an effort to gain further insight into the role of miRNAs in melanoma, we applied Illumina
Externí odkaz:
https://doaj.org/article/05c3999a41684fc4b842c65f93c6e7f6
Autor:
James Kozubek
Would you change your genes if you could? As we confront the'industrial revolution of the genome', the recent discoveries of Crispr-Cas9 technologies are offering, for the first time, cheap and effective methods for editing the human genome. This ope
Autor:
Krystyna Taylor, James Kozubek, Sayoni Das, Mark Strivens, Claus Erik Jensen, Zbigniew Skowron, Marcin Pawlowski, Steve Gardner, Gert Lykke Møller, Matthew Pearson
BACKGROUNDEpidemiological studies indicate that as many as 20% of individuals who test positive for COVID-19 develop severe symptoms that can require hospitalization. These symptoms include low platelet count, severe hypoxia, increased inflammatory c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e36995b8b2bc308d13b4713e7d007f4
Autor:
James Kozubek, Marcin Pawlowski, Sayoni Das, Claus Erik Jensen, Zbigniew Skowron, Steve Gardner, Gert Lykke Møller, Mark Strivens, Matthew Pearson, Krystyna Taylor
BACKGROUNDCoronavirus disease 2019 (COVID-19) is a novel coronavirus strain disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease is highly transmissible and severe disease including viral sepsis has been reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ede62995e6b034d929a189283a8fd03e
https://doi.org/10.1101/2020.05.05.20091918
https://doi.org/10.1101/2020.05.05.20091918
Autor:
James Kozubek
Publikováno v:
Georgetown Journal of International Affairs. 18:112-119
Crispr-Cas9 is a new gene editing technology that can be used to make targeted changes to human genetic material, raising ethical and logistical questions about how best to govern its use.
Publikováno v:
Digital Medicine. 5:180
Background and Objectives: Precision medicine and drug repurposing provide an opportunity to ameliorate the challenges of declining pharmaceutical R&D productivity, rising costs of new drugs, and poor patient response rates to existing medications. M