Zobrazeno 1 - 10
of 35
pro vyhledávání: '"James Koh"'
Autor:
Robert Lowe, Marita G. Overhoff, Sreeram V. Ramagopalan, James C. Garbe, James Koh, Martha R. Stampfer, David H. Beach, Vardhman K. Rakyan, Cleo L. Bishop
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/4e4acf8addd04514a72a64689dc3c3cb
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161134 (2016)
The functional impact of intratumoral heterogeneity has been difficult to assess in the absence of a means to interrogate dynamic, live-cell biochemical events in the native tissue context of a human tumor. Conventional histological methods can revea
Externí odkaz:
https://doaj.org/article/ee3d0299d29b4f62a25da348e090ca36
Autor:
Yvonne M. Kelly, Casey Ward, Run Zhang, Shareef Syed, Peter G. Stock, Quan-Yang Duh, Julie A. Sosa, James Koh
Publikováno v:
The Journal of surgical research. 276
Parathyroid allotransplantation is an emerging treatment for severe hypoparathyroidism. Ensuring the viability and functional integrity of donor parathyroid glands following procurement is essential for optimal transplantation outcomes.Cellular viabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16df7c6519aab053c71a29f0b4d4fbae
https://pubmed.ncbi.nlm.nih.gov/35468367
https://pubmed.ncbi.nlm.nih.gov/35468367
Ex Vivo Intact Tissue Analysis Reveals Alternative Calcium-sensing Behaviors in Parathyroid Adenomas
Autor:
Julie Ann Sosa, Insoo Suh, Sanziana A. Roman, Quan-Yang Duh, James Koh, Jessica E. Gosnell, Run Zhang, Wen T. Shen
Publikováno v:
J Clin Endocrinol Metab
Context The biochemical basis for clinical variability in primary hyperparathyroidism (PHPT) is poorly understood. Objective This study aimed to define parathyroid tumor biochemical properties associated with calcium-sensing failure in PHPT patients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f06f2ceac57ce934cafcd1c65b5648d
https://pubmed.ncbi.nlm.nih.gov/34590700
https://pubmed.ncbi.nlm.nih.gov/34590700
Autor:
Cleo L. Bishop, Bethany K. Hughes, James C. Garbe, Martha R. Stampfer, Robert Lowe, Ana Gutierrez del Arroyo, Ryan Wallis, Michael P. Philpott, Eleanor J. Tyler, James Koh
SummarySenescence, a state of stable growth arrest, plays an important role in ageing and age-related diseases in vivo. Although the INK4/ARF locus is known to be essential for senescence programs, the key regulators driving p16 and ARF transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60756edfdc90e565879a94f825475bae
https://doi.org/10.1101/2020.09.30.321190
https://doi.org/10.1101/2020.09.30.321190
Autor:
Catherine Starks, Jessica E. Gosnell, Sanziana A. Roman, James Koh, Julie Ann Sosa, Run Zhang, Jessica Foft, Jie Zhang
Publikováno v:
Journal of the Endocrine Society
Disruption of calcium homeostasis is common to all forms of hyperparathyroidism (HPT), but the underlying biochemical mechanisms that distinguish the various forms of HPT pathology remain poorly characterized. We previously have observed that the kin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e49e0401353f9773cf79a3d3b17f7d
https://doi.org/10.1210/jendso/bvaa046.526
https://doi.org/10.1210/jendso/bvaa046.526
Autor:
Randall P. Scheri, Sanziana A. Roman, Hélène Fradin, Joyce A. Hogue, James Koh, Julie Ann Sosa, David L. Corcoran
Publikováno v:
Endocrine-related cancer, vol 25, iss 4
The clinical presentation of primary hyperparathyroidism (PHPT) varies widely, although the underlying mechanistic reasons for this disparity remain unknown. We recently reported that parathyroid tumors can be functionally segregated into two distinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c68fbb0ed74936cc7e30f01d63b87f
https://doi.org/10.1530/erc-17-0470
https://doi.org/10.1530/erc-17-0470
Autor:
John A. Olson, Joyce A. Hogue, Nariman Balenga, Pedram Azimzadeh, Joseph P. Stains, James Koh, Mostafa A. Gabr
Publikováno v:
J Bone Miner Res
The relationship between impaired calcium sensing, dysregulated parathyroid hormone (PTH) secretion, and parathyroid cell proliferation in parathyroid neoplasia is not understood. We previously reported that a GTPase activating protein, regulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b971497bb9fdb28f1d15df911d18798e
https://europepmc.org/articles/PMC8210536/
https://europepmc.org/articles/PMC8210536/
Autor:
Paul N. Staats, Holly K. Dressman, John A. Olson, Nariman Balenga, Joyce A. Hogue, Yuhong Shi, Pedram Azimzadeh, James Koh
Publikováno v:
Journal of Bone and Mineral Research. 32:654-666
Abnormal feedback of serum calcium to parathyroid hormone (PTH) secretion is the hallmark of primary hyperparathyroidism (PHPT). Although the molecular pathogenesis of parathyroid neoplasia in PHPT has been linked to abnormal expression of genes invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb6145eaecf4fac0ace7c6c258ba52bd
https://doi.org/10.1002/jbmr.3023
https://doi.org/10.1002/jbmr.3023
Autor:
Yuhong Shi, Nancy L. Allbritton, James Koh, John A. Olson, Joyce A. Hogue, Matthew DiSalvo, Julie Ann Sosa, Yuli Wang
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of cellular and molecular medicine, vol 20, iss 2
Journal of cellular and molecular medicine, vol 20, iss 2
Primary hyperparathyroidism (PHPT) is a common endocrine neoplastic disorder caused by a failure of calcium sensing secondary to tumour development in one or more of the parathyroid glands. Parathyroid adenomas are comprised of distinct cellular subp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbc32358eeb8443fb5ce2199f9f61d92
https://doi.org/10.1111/jcmm.12732
https://doi.org/10.1111/jcmm.12732