Zobrazeno 1 - 3
of 3
pro vyhledávání: '"James Kissling"'
Autor:
C. James Kissling, Stephan Glund, Christian Friedrich, Dominick A. Lionetti, Hans-Juergen Woerle, Sanjay Patel, Julian Righetti, Silke Retlich, Ulrike Graefe-Mody
Publikováno v:
British Journal of Clinical Pharmacology. 76:445-454
Aim This was an open label, multicentre phase I trial to study the pharmacokinetics and pharmacodynamics of the dipeptidyl peptidase-4 (DPP-4) inhibitor linagliptin in African American patients with type 2 diabetes mellitus (T2DM). Methods Forty-one
Publikováno v:
The Journal of Clinical Pharmacology. 49:1408-1416
IDX899 and IDX989 are new non-nucleoside reverse-transcriptase inhibitors (NNRTIs) that exhibit potent inhibition of HIV-1 replication, including NNRTI-resistant mutants. This microdose study investigates the pharmacokinetics and determined oral bioa
Autor:
Aram Oganesian, Gavin Choy, Amarpal Sahai, Scott Rasmussen, Mohammad Azab, Joanne Collier, James Kissling, Rajashree Joshi-Hangal, Gil Fine, Sanjeev Redkar
Publikováno v:
Cancer chemotherapy and pharmacology. 70(1)
Amuvatinib is a multi-targeted tyrosine kinase inhibitor with activity that also disrupts DNA damage repair through suppression of homologous recombination protein Rad51. Amuvatinib dry-powder capsules (DPC) showed evidence of activity in early Phase