Zobrazeno 1 - 9
of 9
pro vyhledávání: '"James Kile"'
Autor:
Ann Carpenter, Michelle A. Waltenburg, Aron Hall, James Kile, Marie Killerby, Barbara Knust, Maria Negron, Megin Nichols, Ryan M. Wallace, Casey Barton Behravesh, Jennifer H. McQuiston, the Vaccine Preventable Zoonotic Disease Working Group
Publikováno v:
Vaccines, Vol 10, Iss 7, p 993 (2022)
Zoonotic diseases represent a heavy global burden, causing important economic losses, impacting animal health and production, and costing millions of human lives. The vaccination of animals and humans to prevent inter-species zoonotic disease transmi
Externí odkaz:
https://doaj.org/article/032daba4133749e1bfaae22785e62b4c
Autor:
Sharmi W Thor, Hieu Nguyen, Amanda Balish, Anh Nguyen Hoang, Kortney M Gustin, Pham Thi Nhung, Joyce Jones, Ngoc Nguyen Thu, William Davis, Thao Nguyen Thi Ngoc, Yunho Jang, Katrina Sleeman, Julie Villanueva, James Kile, Larisa V Gubareva, Stephen Lindstrom, Terrence M Tumpey, C Todd Davis, Nguyen Thanh Long
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133867 (2015)
Highly pathogenic avian influenza (HPAI) H5N1 is endemic in Vietnamese poultry and has caused sporadic human infection in Vietnam since 2003. Human infections with HPAI H5N1 are of concern due to a high mortality rate and the potential for the emerge
Externí odkaz:
https://doaj.org/article/9d16ddcf2da84c269e6f885fb2dc1a53
Autor:
Sarah B. Crist, Karim Azzag, James Kiley, Ilsa Coleman, Alessandro Magli, Rita C. R. Perlingeiro
Publikováno v:
npj Regenerative Medicine, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Pluripotent stem cell (PSC)-based cell therapy is an attractive option for the treatment of multiple human disorders, including muscular dystrophies. While in vitro differentiating PSCs can generate large numbers of human lineage-specific ti
Externí odkaz:
https://doaj.org/article/3ac59d76d3d74db5b598651beb2c7b74
Publikováno v:
Cells, Vol 13, Iss 11, p 972 (2024)
Mutations in the DMD gene cause fatal Duchenne Muscular Dystrophy (DMD). An attractive therapeutic approach is autologous cell transplantation utilizing myogenic progenitors derived from induced pluripotent stem cells (iPSCs). Given that a significan
Externí odkaz:
https://doaj.org/article/8c4239b814e34c778036e237865d9511
Establishment of Skeletal Myogenic Progenitors from Non-Human Primate Induced Pluripotent Stem Cells
Autor:
June Baik, Carolina Ortiz-Cordero, Alessandro Magli, Karim Azzag, Sarah B. Crist, Aline Yamashita, James Kiley, Sridhar Selvaraj, Ricardo Mondragon-Gonzalez, Elizabeth Perrin, John P. Maufort, Jody L. Janecek, Rachael M. Lee, Laura Hocum Stone, Parthasarathy Rangarajan, Sabarinathan Ramachandran, Melanie L. Graham, Rita C. R. Perlingeiro
Publikováno v:
Cells, Vol 12, Iss 8, p 1147 (2023)
Pluripotent stem (PS) cells enable the scalable production of tissue-specific derivatives with therapeutic potential for various clinical applications, including muscular dystrophies. Given the similarity to human counterparts, the non-human primate
Externí odkaz:
https://doaj.org/article/ca90a32d1b4844d29800015a149982ef
Autor:
Neha R. Dhoke, Hyunkee Kim, Sridhar Selvaraj, Karim Azzag, Haowen Zhou, Nelio A.J. Oliveira, Sudheer Tungtur, Carolina Ortiz-Cordero, James Kiley, Qi Long Lu, Anne G. Bang, Rita C.R. Perlingeiro
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109360- (2021)
Summary: Mutations in the fukutin-related protein (FKRP) gene result in a broad spectrum of muscular dystrophy (MD) phenotypes, including the severe Walker-Warburg syndrome (WWS). Here, we develop a gene-editing approach that replaces the entire muta
Externí odkaz:
https://doaj.org/article/6c28b824295349c796db8b9112b5789f
Autor:
Robert P. Hebbel, Peng Wei, Liming Milbauer, Michel T. Corban, Anna Solovey, James Kiley, Jack Pattee, Lilach O. Lerman, Wei Pan, Amir Lerman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 14 (2020)
Background We examined feasibility of a unique approach towards gaining insight into heritable risk for early atherosclerosis: surveying gene expression by endothelial cells from living subjects. Methods and Results Subjects aged
Externí odkaz:
https://doaj.org/article/d576101cb31647759c587fe68362a3d5
Autor:
Alessandro Magli, Tania Incitti, James Kiley, Scott A. Swanson, Radbod Darabi, Fabrizio Rinaldi, Sridhar Selvaraj, Ami Yamamoto, Jakub Tolar, Ce Yuan, Ron Stewart, James A. Thomson, Rita C.R. Perlingeiro
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2867-2877 (2017)
Pluripotent stem (PS)-cell-derived cell types hold promise for treating degenerative diseases. However, PS cell differentiation is intrinsically heterogeneous; therefore, clinical translation requires the development of practical methods for isolatin
Externí odkaz:
https://doaj.org/article/70614948bf39434b9fc02261805bfe17
Autor:
Sridhar Selvaraj, Ricardo Mondragon-Gonzalez, Bin Xu, Alessandro Magli, Hyunkee Kim, Jeanne Lainé, James Kiley, Holly Mckee, Fabrizio Rinaldi, Joy Aho, Nacira Tabti, Wei Shen, Rita CR Perlingeiro
Publikováno v:
eLife, Vol 8 (2019)
Targeted differentiation of pluripotent stem (PS) cells into myotubes enables in vitro disease modeling of skeletal muscle diseases. Although various protocols achieve myogenic differentiation in vitro, resulting myotubes typically display an embryon
Externí odkaz:
https://doaj.org/article/a01d54454c94430f87c88ae4b338d0e1