Zobrazeno 1 - 7
of 7
pro vyhledávání: '"James Karl A. Till"'
Autor:
Ju-Sim Kim, Alexandra Born, James Karl A. Till, Lin Liu, Sashi Kant, Morkos A. Henen, Beat Vögeli, Andrés Vázquez-Torres
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The response regulator SsrB, a master activator of the Salmonella pathogenicity island-2 gene cluster, is under allosteric control of thioredoxin. Authors utilise in vitro and in vivo models to investigate if other members of the response regulator f
Externí odkaz:
https://doaj.org/article/0efe26c693194b90b5cbf85edd28c641
Autor:
Alyssa Margolis, Lin Liu, Steffen Porwollik, James Karl A. Till, Weiping Chu, Michael McClelland, Andrés Vázquez-Torres
Publikováno v:
Infection and Immunity.
Salmonella invades host cells and replicates inside acidified, remodeled vacuoles that are exposed to reactive oxygen species (ROS) generated by the innate immune response. Oxidative products of the phagocyte NADPH oxidase mediate antimicrobial activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68eaae2e4e8f5aaa6a48e95e5e68b4d1
https://doi.org/10.1128/iai.00120-23
https://doi.org/10.1128/iai.00120-23
Detoxification, scavenging and repair systems embody the archetypical antioxidant defenses of prokaryotic and eukaryotic cells1–3. Metabolic rewiring is an emergent aspect in the adaptation of bacteria to oxidative stress4, 5. Evolutionarily divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85663c817f1ff4e02835bab0c3fa1df6
https://doi.org/10.1101/2022.06.09.495436
https://doi.org/10.1101/2022.06.09.495436
Autor:
Sashi Kant, James Karl A. Till, Lin Liu, Alyssa Margolis, Siva Uppalapati, Ju-Sim Kim, Andres Vazquez-Torres
Publikováno v:
PLOS Biology. 21:e3002051
Detoxification, scavenging, and repair systems embody the archetypical antioxidant defenses of prokaryotic and eukaryotic cells. Metabolic rewiring also aids with the adaptation of bacteria to oxidative stress. Evolutionarily diverse bacteria combat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f0e5570124bedcb51fd97f5fc3c586d
https://doi.org/10.1371/journal.pbio.3002051
https://doi.org/10.1371/journal.pbio.3002051
Autor:
Tyler Offerman, Christopher D. Murakami, Arlo Bradley Simonds, Deion Jones, Kelly Ann Walsh, Erica Lynn Klopf, James Karl A Till, Tia Rowe, Lori Boegershausen
Publikováno v:
Education for Sustainability ISBN: 9789813344761
Universities should use their economic and social leveraging power to support the development of sustainable food systems. Conventional, industrial food systems are often responsible for environmental degradation, inhumane treatment of animals, explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e31786f20e5faa5382355a6b22c5c51d
https://doi.org/10.1007/978-981-33-4477-8_12
https://doi.org/10.1007/978-981-33-4477-8_12
Autor:
Ju-Sim Kim, Sashi Kant, Lin Liu, Jessica Jones-Carson, Steffen Porwollik, Michael McClelland, Liam F. Fitzsimmons, James Karl A Till, Andrés Vázquez-Torres
Publikováno v:
mBio, vol 11, iss 1
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1, p e03397-19 (2020)
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1, p e03397-19 (2020)
Guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), together named (p)ppGpp, regulate diverse aspects of Salmonella pathogenesis, including synthesis of nutrients, resistance to inflammatory mediators, and expression of secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb291b6248c12c6a315d6be72a1afe9
https://escholarship.org/uc/item/044573x6
https://escholarship.org/uc/item/044573x6
Autor:
James Karl A Till, Ju-Sim Kim, Shaodong Dai, Matthew A. Crawford, Madia Trujillo, Andrés Vázquez-Torres, Mauricio Mastrogiovanni, Lin Liu, Rafael Radi, Yang Wang, Liam F. Fitzsimmons
Publikováno v:
Proceedings of the National Academy of Sciences. 115
RNA polymerase is the only known protein partner of the transcriptional regulator DksA. Herein, we demonstrate that the chaperone DnaJ establishes direct, redox-based interactions with oxidized DksA. Cysteine residues in the zinc finger of DksA becom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a285953217431d2110635af027c555e9
https://doi.org/10.1073/pnas.1813572115
https://doi.org/10.1073/pnas.1813572115