Zobrazeno 1 - 10
of 94
pro vyhledávání: '"James K. Sutherland"'
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2861-2870
The conversion of (1S, 2S)-3-bromocyclohexa-3,5-diene-1,2-diol, (5S, 6S)-5,6-dihydroxycyclohexa-1,3-diene-1-carbonitrile and methyl (5S,6S)-5,6-dihydroxycyclohexa-1,3-diene-l-carboxylate into 6β-hydroxyshikimic acid and protected derivatives is desc
Publikováno v:
Tetrahedron. 49:8233-8240
Tricyclic cyclohexa-2,4-dienones and methylenecyclohexadienes which are potentially useful for diterpenoid synthesis have been prepared by cyclisation of 1,3,5-hexatriene-1-ones and 1,2,4,6-heptatetraenes.
Autor:
Kathryn Carr, James K. Sutherland, Khairuzzaman B. Mullah, Neil A. Greener, Fiona M. Somerville
Publikováno v:
ChemInform. 23
2-Acetyl-1,4-dihydroxyanthracene-9,10-dione 1 is converted into (±)-demethoxydaunomycinone by substitution with 3,3-dimethoxy-1-nitrobutan-2-one, aldol cyclisation, reduction and hydrolysis. The chiral inductions at C-10 realised on cyclisation of 5
Publikováno v:
ChemInform. 22
On thermolysis, 2-hydroxy-1-isopropyl-2-vinylbicyclo[4.3.0]non-6-en-8-one 18 undergoes oxy-Cope rearrangement followed by an ‘ene’ reaction to give 5-hydroxy-11-isopropyl-8-methyltricyclo[6.3.0.01,5]undec-10-ene-9-one 21, which is cleaved by Pb(O
Publikováno v:
ChemInform. 22
Autor:
Jill Barber, James K. Sutherland, David A. Pye, Jeffrey I. Gyi, Lu-Yun Lian, Gareth A. Morris
Publikováno v:
ChemInform. 23
The 1H and 13C NMR spectra of erythromycin A in [2H6]-DMSO and buffered D2O have been assigned using a range of one and two dimensional NMR techniques. Assignments have been made for both the major (keto) and minor forms of the drug, and the minor fo
Publikováno v:
ChemInform. 23
Cholic and chenodeoxycholic acids have been transformed into analogues of the anti-fungal aza steroid A25822A via the 8(14)-ene and 8,14-diene derivatives.
Publikováno v:
ChemInform. 23
Reaction of 2-acetyl-1,4-dihydroxyanthraquinone with a variety of β-keto esters in presence of tertiary amine in MeOH afforded anthracyclinone derivatives in a one-pot addition–oxidation–aldol sequence.
Publikováno v:
ChemInform. 25
Tricyclic cyclohexa-2,4-dienones and methylenecyclohexadienes which are potentially useful for diterpenoid synthesis have been prepared by cyclisation of 1,3,5-hexatriene-1-ones and 1,2,4,6-heptatetraenes.
Publikováno v:
ChemInform. 26
Two synthetic routes to the methyl ketone 30 from the dione 2 are described. Compound 30 is a potential precursor of 4-demethylforskolin.