Zobrazeno 1 - 10
of 61
pro vyhledávání: '"James K. Roche"'
Autor:
Luther A Bartelt, David T Bolick, Glynis L Kolling, James K Roche, Edna I Zaenker, Ana M Lara, Francisco Jose Noronha, Carrie A Cowardin, John H Moore, Jerrold R Turner, Cirle A Warren, Gregory A Buck, Richard L Guerrant
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 7, p e0004820 (2016)
Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the eff
Externí odkaz:
https://doaj.org/article/f0edf21ea617435ea428c1422f1a8969
Autor:
Orleâncio G R Azevedo, David T Bolick, James K Roche, Relana F Pinkerton, Aldo A M Lima, Michael P Vitek, Cirle A Warren, Reinaldo B Oriá, Richard L Guerrant
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89562 (2014)
Apolipoliprotein E (apoE), a critical targeting protein in lipid homeostasis, has been found to have immunoinflammatory effects on murine models of infection and malnutrition. The effects of apoE in undernourished and Cryptosporidium parvum-infected
Externí odkaz:
https://doaj.org/article/d99aa34025844ac7a61aee2cf836975f
Autor:
Casandra W Philipson, Josep Bassaganya-Riera, Monica Viladomiu, Mireia Pedragosa, Richard L Guerrant, James K Roche, Raquel Hontecillas
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57812 (2013)
Enteroaggregative Escherichia coli (EAEC) is recognized as an emerging cause of persistent diarrhea and enteric disease worldwide. Mucosal immunity towards EAEC infections is incompletely understood due in part to the lack of appropriate animal model
Externí odkaz:
https://doaj.org/article/195041305b574fdbbb28258bef1e6905
Autor:
Monica Viladomiu, Raquel Hontecillas, Mireia Pedragosa, Adria Carbo, Stefan Hoops, Pawel Michalak, Katarzyna Michalak, Richard L Guerrant, James K Roche, Cirle A Warren, Josep Bassaganya-Riera
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47525 (2012)
Clostridium difficile is an anaerobic bacterium that has re-emerged as a facultative pathogen and can cause nosocomial diarrhea, colitis or even death. Peroxisome proliferator-activated receptor (PPAR) γ has been implicated in the prevention of infl
Externí odkaz:
https://doaj.org/article/42b0dad33ca8470fab3574a64c9456ce
Autor:
James K. Roche
Publikováno v:
Inflammatory Cells and Lung Disease ISBN: 9780429274435
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13712c08facd01bf191575a7186ff4c
https://doi.org/10.1201/9780429274435-3
https://doi.org/10.1201/9780429274435-3
Autor:
Caio Calixto Diógenes Pinheiro, Francisco Jose Noronha, Pedro H. Q. S. Medeiros, Glynis L. Kolling, David T. Bolick, James K. Roche, Aldo A. M. Lima, Richard L. Guerrant
Publikováno v:
Virulence
Enteroaggregative Escherichia coli (EAEC) is a major pathogen worldwide, associated with diarrheal disease in both children and adults, suggesting the need for new preventive and therapeutic treatments. We investigated the role of the micronutrient z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e14e128c4e47526505cec3c6b905e9
https://doi.org/10.4161/viru.26120
https://doi.org/10.4161/viru.26120
Autor:
John H. Moore, Carrie A. Cowardin, David T. Bolick, Gregory A. Buck, Jerrold R. Turner, James K. Roche, Ana M. Lara, Francisco Jose Noronha, Glynis L. Kolling, Cirle A. Warren, Luther A. Bartelt, Edna I. Zaenker, Richard L. Guerrant
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 10, Iss 7, p e0004820 (2016)
PLoS Neglected Tropical Diseases, Vol 10, Iss 7, p e0004820 (2016)
Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab83c391e8b2acf315d9760b67ead64
http://europepmc.org/articles/PMC4965189
http://europepmc.org/articles/PMC4965189
Publikováno v:
Journal of Applied Gerontology. 30:67-84
This study assesses three hypotheses regarding a long-term care facility’s ethics environment and the relationships between ethics environment, employees’ work features, and residents’ outcomes. Validated questionnaires measure ethics environme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a78282e60ff0ae9c8586f43664a8c8f
https://doi.org/10.1177/0733464810361464
https://doi.org/10.1177/0733464810361464
Autor:
Tom G. Obrig, Regina M. Seaner, Seth H. Pincus, Matthew K. Stone, James K. Roche, Lisa K. Gross, Matthew H. Lindner
Publikováno v:
Laboratory Investigation. 88:1178-1191
The role of the liver in fatal intoxication with the binary toxin ricin is undefined. Means to reverse pathological events in the liver and to gain host survival after exposure to this toxin have not been described. We report a robust 7/4+ neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67b12d8c60b071a9a622825ddfaf861
https://doi.org/10.1038/labinvest.2008.83
https://doi.org/10.1038/labinvest.2008.83
Autor:
James K. Roche, Adam H. Johnson, Henry F. Frierson, Steven M. Powell, Wael El-Rifai, Sheila E. Crowe, Alexander Zaika, Christopher A. Moskaluk
Publikováno v:
The American Journal of Pathology. 167:577-584
Trefoil factor-1 (Tff1) expression is remarkably down-regulated in nearly all human gastric cancers. Therefore, we used the Tff1 knockout mouse model to detect molecular changes in preneoplastic gastric dysplasia. Oligonucleotide microarray gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1533640d604e2ee527d6a294bdd24de5
https://doi.org/10.1016/s0002-9440(10)62999-9
https://doi.org/10.1016/s0002-9440(10)62999-9