Zobrazeno 1 - 10
of 30
pro vyhledávání: '"James K. Pretorius"'
Autor:
Monica Florio, Kannan Gunasekaran, Marina Stolina, Xiaodong Li, Ling Liu, Barbara Tipton, Hossein Salimi-Moosavi, Franklin J. Asuncion, Chaoyang Li, Banghua Sun, Hong Lin Tan, Li Zhang, Chun-Ya Han, Ryan Case, Amy N. Duguay, Mario Grisanti, Jennitte Stevens, James K. Pretorius, Efrain Pacheco, Heidi Jones, Qing Chen, Brian D. Soriano, Jie Wen, Brenda Heron, Frederick W. Jacobsen, Emil Brisan, William G. Richards, Hua Zhu Ke, Michael S. Ominsky
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Antibodies that block the Wnt inhibitors sclerostin and DKK- 1 enhance bone formation and fracture repair. Here the authors show these monospecific antibodies induce compensatory mechanisms that limit efficacy, and have designed a sclerostin/DKK-1 bi
Externí odkaz:
https://doaj.org/article/5b80b8c1d296447f878d119b9b8140cb
Autor:
Gary W. Mathern, James K. Pretorius, Harley I. Kornblum, Delia Mendoza, Alana Lozada, Joao P. Leite, Leila Chimelli, Donald E. Born, Itzhak Fried, Americo C. Sakamoto, Joao A. Assirati, Warwick J. Peacock, George A. Ojemann, P.David Adelson
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 3, Pp 151-176 (1998)
This study determined whether hippocampal kainate (KA) receptor mRNA levels were increased or decreased in temporal lobe epilepsy patients compared with nonseizure autopsies. Hippocampal sclerosis (HS;n= 17), nonsclerosis (non-HS;n= 11), and autopsy
Externí odkaz:
https://doaj.org/article/b731394ad3e94018b3ad02a2fb55b573
Autor:
Harley I. Kornblum, Donald E. Born, George A. Ojemann, João Alberto Assirati, Leila Chimelli, Gary W. Mathern, P. David Adelson, Itzhak Fried, Delia Mendoza, James K. Pretorius, Leslie D. Cahan, João Pereira Leite
Publikováno v:
Annals of Neurology. 46:343-358
Changes in the subunit stoichiometry of the N-methyl-D-aspartate (NMDA) receptor (NMDAR) alters its channel properties, and may enhance or reduce neuronal excitability in temporal lobe epilepsy patients. This study determined whether hippocampal NMDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::891a5df3b83cdfa64d93101d8ebd15c2
https://doi.org/10.1002/1531-8249(199909)46:3<343::aid-ana10>3.0.co
https://doi.org/10.1002/1531-8249(199909)46:3<343::aid-ana10>3.0.co
Publikováno v:
Journal of Neuroscience Research. 54:734-753
There is considerable controversy whether aberrant fascia dentata (FD) mossy fiber sprouting is an epiphenomena related to neuronal loss or a pathologic abnormality responsible for spontaneous limbic seizures. If mossy fiber sprouting contributes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ae6c3f824e11cbceb88d2d291852286
https://doi.org/10.1002/(sici)1097-4547(19981215)54:6<734::aid-jnr2>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19981215)54:6<734::aid-jnr2>3.0.co
Autor:
Warwick J. Peacock, Gary W. Mathern, George A. Ojemann, Leila Chimelli, Itzhak Fried, Alana Lozada, Donald E. Born, Américo Ceiki Sakamoto, João Pereira Leite, João Alberto Assirati, Delia Mendoza, James K. Pretorius, P. David Adelson, Harley I. Kornblum
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 3, Pp 151-176 (1998)
This study determined whether hippocampal kainate (KA) receptor mRNA levels were increased or decreased in temporal lobe epilepsy patients compared with nonseizure autopsies. Hippocampal sclerosis (HS; n = 17), nonsclerosis (non-HS; n = 11), and auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a0ed36f9db359a91ee8a3614062861
http://www.sciencedirect.com/science/article/pii/S0969996198902005
http://www.sciencedirect.com/science/article/pii/S0969996198902005
Autor:
Harley I. Kornblum, Edward H. Bertram, Gary W. Mathern, Delia Mendoza, James K. Pretorius, Alana Lozada, João Pereira Leite
Publikováno v:
Epilepsy Research. 32:154-171
This study compared temporal lobe epilepsy patients, along with kindled animals and self sustained limbic status epilepticus (SSLSE) rats for parallels in hippocampal AMPA and NMDA receptor subunit expression. Hippocampal sclerosis patients (HS), non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6601f20367c168c6a92bd6dd0282a540
https://doi.org/10.1016/s0920-1211(98)00048-5
https://doi.org/10.1016/s0920-1211(98)00048-5
Publikováno v:
Journal of Neuropathology and Experimental Neurology. 56:199-212
This study determined fascia dentata anatomy and hippocampal neuron densities in patients with different epileptic syndromes. Based on presurgical data, patients were classified into: (a) pediatric patients (n=19); (b) temporal mass lesion cases (n=1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8b822eca56d4c0db19740a189ea8d0
https://doi.org/10.1097/00005072-199702000-00011
https://doi.org/10.1097/00005072-199702000-00011
Autor:
Gary W. Mathern, Paula A. Kuhlman, Thomas L. Babb, Edward H. Bertram, Delia Mendoza, James K. Pretorius, S Spradlin
Publikováno v:
Neuroscience. 77:1003-1019
This study determined whether there were differences in hippocampal neuron loss and synaptic plasticity by comparing rats with spontaneous epilepsy after limbic status epilepticus and animals with a similar frequency of kindled seizures. At the Unive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e7f94eafa80aa106b93398d09b2ed5
https://doi.org/10.1016/s0306-4522(96)00516-7
https://doi.org/10.1016/s0306-4522(96)00516-7
Publikováno v:
Molecular and Chemical Neuropathology. 30:53-76
This study determined in temporal lobe epilepsy patients if there were correlations among hippocampal granule cell expression of neurotrophin mRNAs, aberrant supragranular mossy fiber sprouting, and neuron losses. Consecutive surgically resected hipp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff775da88623dffe02c0950c4818d63
https://doi.org/10.1007/bf02815150
https://doi.org/10.1007/bf02815150
Autor:
Gary W. Mathern, Harry V. Vinters, James K. Pretorius, Thomas L. Babb, Paul S. Mischel, João Pereira Leite, Warwick J. Peacock
Publikováno v:
Brain. 119:965-987
Summary In this study, we determined whether childhood seizures were associated with hippocampal neuron loss and mossy fibre synaptic reorganization and if hippocampal sclerosis evolved from longer seizure histories. Children undergoing surgical trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba9ba1ede4ae8eb461a3e3a960e1b67
https://doi.org/10.1093/brain/119.3.965
https://doi.org/10.1093/brain/119.3.965