Zobrazeno 1 - 10
of 160
pro vyhledávání: '"James K, Rowlett"'
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/e7e4a164a19e4959a9f2c65a505c997a
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionBenzodiazepines (BZs) are prescribed as anxiolytics, but their use is limited by side effects including abuse liability and daytime drowsiness. Neuroactive steroids are compounds that, like BZs, modulate the effects of GABA at the GABAA r
Externí odkaz:
https://doaj.org/article/c55cfd91072240c591fcfdd7d04a814c
Autor:
Kerry L. Kinney, Yufeng Zheng, Matthew C. Morris, Julie A. Schumacher, Saurabh B. Bhardwaj, James K. Rowlett
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionBenzodiazepines are the most commonly prescribed psychotropic medications, but they may place users at risk of serious adverse effects. Developing a method to predict benzodiazepine prescriptions could assist in prevention efforts.Methods
Externí odkaz:
https://doaj.org/article/bd76bb48a6224ab9acfb2ca8aa565c0c
Autor:
Caio Jovita-Farias, Meagan E. Follett, Behaim C. Dias-Junior, Yasmim A. Serra, Natali D. Kisaki, Thaísa Barros-Santos, Nailton M. S. de Jesus, Isa R. S. Rodrigues, Larissa E. L. Macedo, Elena L. A. Malpezzi-Marinho, Alexandre J. Oliveira-Lima, Eduardo Ary Villela Marinho, James K. Rowlett, Lais F. Berro
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionThe aim of the present study was to investigate the behavioral effects of the benzodiazepine midazolam in male mice, in models of anxiolysis, learning, and abuse-related effects.MethodsIn a first set of experiments, male Swiss mice were s
Externí odkaz:
https://doaj.org/article/071797bab38a4d0b8a89aaa9c1bfbd7b
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Use of amphetamine-type stimulants is associated with numerous adverse health outcomes, with disturbed sleep being one of the most prominent consequences of methamphetamine use. However, the extent to which methamphetamine alters sleep architecture,
Externí odkaz:
https://doaj.org/article/c8b64f0c373d4c579c06b431cf7accdd
Autor:
Lalit K. Golani, Donna M. Platt, Daniela Rüedi-Bettschen, Chitra Edwanker, Shenming Huang, Michael M. Poe, Roman Furtmüller, Werner Sieghart, James M. Cook, James K. Rowlett
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
In order to develop improved anxiolytic drugs, 8-substituted analogs of triazolam were synthesized in an effort to discover compounds with selectivity for α2/α3 subunit-containing GABAA subtypes. Two compounds in this series, XLi-JY-DMH (6-(2-chlor
Externí odkaz:
https://doaj.org/article/a95252a7ff224cdca9d223b58e02c490
Autor:
C. Austin Zamarripa, William S. Doyle, Kevin B. Freeman, James K. Rowlett, Sally L. Huskinson
Publikováno v:
Experimental and Clinical Psychopharmacology. 31:204-218
Illicit drugs like cocaine may be uncertain in terms of the time and effort required to obtain them. Behavior maintained by variable schedules resembles excessive drug-taking compared with fixed schedules. However, no prior research has examined fixe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72be370bc396a2d0d1cfd01bd0495477
https://doi.org/10.1037/pha0000547
https://doi.org/10.1037/pha0000547
Autor:
Lais F Berro, Tanya Pareek, Jaren A Reeves-Darby, Monica L Andersen, Leonard L Howell, Donna M Platt, James K Rowlett
Publikováno v:
J Am Assoc Lab Anim Sci
Rhesus monkeys are naturally social animals, and behavioral management strategies have focused on promoting pairhousing in laboratory settings as an alternative to individual or group housing. In humans, co-sleeping can have a major impact on bed par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586eb46dfe952d09b4742ef27f360f95
https://doi.org/10.30802/aalas-jaalas-21-000027
https://doi.org/10.30802/aalas-jaalas-21-000027
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Benzodiazepines induce electroencephalography (EEG) changes in rodents and humans that are associated with distinct behavioral effects and have been proposed as quantitative biomarkers for GABA(A) receptor modulation. Specifically, central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc17c831344227f6ea9be6568cbc02c
https://doi.org/10.1007/s00213-021-05793-z
https://doi.org/10.1007/s00213-021-05793-z
Autor:
Laurie J. Lynch, Katherine A. Sullivan, Eric J. Vallender, James K. Rowlett, Donna M. Platt, Gregory M. Miller
Publikováno v:
Substance Abuse: Research and Treatment, Vol 2013, Iss 7, Pp 117-126 (2013)
Externí odkaz:
https://doaj.org/article/02311b402b12402693ee31daa3b66e7c