Zobrazeno 1 - 10
of 123
pro vyhledávání: '"James K, Drennen"'
Autor:
Sandeep Kumar Reddy Adena, Michele Herneisey, Eric Pierce, Paul R. Hartmeier, Suneera Adlakha, Marco A. I. Hosfeld, James K. Drennen, Jelena M. Janjic
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 880 (2021)
In the presented study, we report development of a stable, scalable, and high-quality curcumin-loaded oil/water (o/w) nanoemulsion manufactured by concentration-mediated catastrophic phase inversion as a low energy nanoemulsification strategy. A desi
Externí odkaz:
https://doaj.org/article/8b258132a38642d9a798bad2ac3436c0
Autor:
Suyang Wu, Stephanie A. Ketcham, Claudia C. Corredor, Douglas Both, James K. Drennen, Carl A. Anderson
Publikováno v:
Biotechnology and Bioengineering. 119:857-867
Cell death is one of the failure modes of mammalian cell culture. Apoptosis is a regulated cell death process mainly observed in cell culture. Timely detection of apoptosis onset allows opportunities for preventive controls that ensure high productiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee813b6af3ea601e5bd9edebacd8b8b
https://doi.org/10.1002/bit.28011
https://doi.org/10.1002/bit.28011
Autor:
Sameer, Talwar, Pallavi, Pawar, Huiquan, Wu, Koushik, Sowrirajan, Suyang, Wu, Benoît, Igne, Richard, Friedman, Fernando J, Muzzio, James K, Drennen
Publikováno v:
The AAPS Journal. 24
An online near-infrared (NIR) spectroscopy platform system for real-time powder blending monitoring and blend endpoint determination was tested for a phenytoin sodium formulation. The study utilized robust experimental design and multiple sensors to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06fa8c6013525a0fb72478d4d072cf8f
https://doi.org/10.1208/s12248-022-00748-4
https://doi.org/10.1208/s12248-022-00748-4
Autor:
Suyang Wu, Stephanie A Ketcham, Claudia C. Corredor, Douglas Both, James K. Drennen, Carl A. Anderson
Publikováno v:
Biotechnology journal.
Previous work developed a quantitative model using capacitance spectroscopy in an at-line setup to predict the dying cell percentage measured from a flow cytometer. This work aimed to transfer the at-line model to monitor lab-scale bioreactors in rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a2be7640504c8c5d6b274c1008f51e
https://pubmed.ncbi.nlm.nih.gov/36479620
https://pubmed.ncbi.nlm.nih.gov/36479620
Publikováno v:
The AAPS Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a0f951eccbdbca8466edd1f278927f
https://doi.org/10.1208/s12248-022-00725-x
https://doi.org/10.1208/s12248-022-00725-x
Autor:
Michele Herneisey, Eric Lambert, Allison Kachel, Emma Shychuck, James K. Drennen, Jelena M. Janjic
Publikováno v:
Molecules, Vol 24, Iss 11, p 2066 (2019)
The development of pharmaceutical nanoformulations has accelerated over the past decade. However, the nano-sized drug carriers continue to meet substantial regulatory and clinical translation challenges. In order to address some of these key challeng
Externí odkaz:
https://doaj.org/article/b08d509efc7d4675bf5302bd9099992a
Autor:
Hanzhou Feng, Yi Li, Eiji Kato, Nayeem Hossain, Carl A. Anderson, Noritaka Odani, Shikhar Mohan, James K. Drennen
Publikováno v:
Analytical Chemistry. 92:3658-3665
Near infrared spectroscopy (NIRS) is often used during the tablet coating process to assess coating thickness. As the coating process proceeds, the increase and decrease in NIRS signal from both the coating formulation and tablet core has been relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be818efa45f478e4977f00694a357957
https://doi.org/10.1021/acs.analchem.9b04750
https://doi.org/10.1021/acs.analchem.9b04750
Autor:
Carl A. Anderson, Shikhar Mohan, Yi Li, James K. Drennen, Noritaka Odani, Eiji Kato, Hanzhou Feng, Md. Nayeem Hossain
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 145:35-41
Film coating of nifedipine tablets is commonly performed to reduce photo-degradation. The coating thickness of these tablets is a primary dictating factor of photo-stability. Terahertz spectroscopy enables accurate measurement of coating thickness. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d982599267681fbcdbf209e613f6891
https://doi.org/10.1016/j.ejpb.2019.09.024
https://doi.org/10.1016/j.ejpb.2019.09.024
Publikováno v:
International journal of pharmaceutics. 614
As continuous manufacturing (CM) processes are developed, process analytical technology (PAT) via NIR spectroscopy has become an integral tool in process monitoring. NIR spectroscopy requires the deployment of complex multivariate models to extract t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc06ddcdd469f2aac27867c7ae0043ff
https://pubmed.ncbi.nlm.nih.gov/35026311
https://pubmed.ncbi.nlm.nih.gov/35026311
