Zobrazeno 1 - 10
of 26
pro vyhledávání: '"James Jafali"'
Autor:
Segun Fatumo, Dassen Sathan, Chaimae Samtal, Itunuoluwa Isewon, Tsaone Tamuhla, Chisom Soremekun, James Jafali, Sumir Panji, Nicki Tiffin, Yasmina Jaufeerally Fakim
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Early identification of genetic risk factors for complex diseases can enable timely interventions and prevent serious outcomes, including mortality. While the genetics underlying many Mendelian diseases have been elucidated, it is harder to
Externí odkaz:
https://doaj.org/article/47b31cded7804d7dab44f1398fc35771
Autor:
Ben Morton, Kayla G. Barnes, Catherine Anscombe, Khuzwayo Jere, Prisca Matambo, Jonathan Mandolo, Raphael Kamng’ona, Comfort Brown, James Nyirenda, Tamara Phiri, Ndaziona P. Banda, Charlotte Van Der Veer, Kwazizira S. Mndolo, Kelvin Mponda, Jamie Rylance, Chimota Phiri, Jane Mallewa, Mulinda Nyirenda, Grace Katha, Paul Kambiya, James Jafali, Henry C. Mwandumba, Stephen B. Gordon, Blantyre COVID-19 Consortium, Jennifer Cornick, Kondwani C. Jambo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Clinical management of COVID-19 in resource-poor settings has distinct challenges and detailed patient characterisation is needed. Here, the authors describe the clinical and immunological profiles of patients at a hospital in Malawi with confirmed a
Externí odkaz:
https://doaj.org/article/5ac0ac388c3f4d77be678f53c3d46ebe
Autor:
Ebrima Bojang, James Jafali, Vincent Perreten, John Hart, Emma M. Harding-Esch, Ansumana Sillah, David C. W. Mabey, Martin J. Holland, Robin L. Bailey, Anna Roca, Sarah E. Burr
Publikováno v:
BMC Microbiology, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Mass drug administration (MDA) with azithromycin is a corner-stone of trachoma control however it may drive the emergence of antimicrobial resistance. In a cluster-randomized trial (Clinical trial gov NCT00792922), we compared the
Externí odkaz:
https://doaj.org/article/7b3342338ed5480d8046320ff0f85996
Autor:
Widad Dantoft, Pablo Martínez-Vicente, James Jafali, Lara Pérez-Martínez, Kim Martin, Konstantinos Kotzamanis, Marie Craigon, Manfred Auer, Neil T. Young, Paul Walsh, Arnaud Marchant, Ana Angulo, Thorsten Forster, Peter Ghazal
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Neonates and especially premature infants are highly susceptible to infection but still can have a remarkable resilience that is poorly understood. The view that neonates have an incomplete or deficient immune system is changing. Human neonatal studi
Externí odkaz:
https://doaj.org/article/d9077d58e65b4a29a7a12f22c62445c4
Autor:
Abdoulie Bojang, James Jafali, Uzochukwu E Egere, Phillip C Hill, Martin Antonio, David Jeffries, Brian M Greenwood, Anna Roca
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0129649 (2015)
We conducted an ancillary study among individuals who had participated in a PCV-7 trial in rural Gambia, to determine the influence of season on the prevalence of pneumococcal carriage.636 individuals above 30 months of age were followed from 4 to 20
Externí odkaz:
https://doaj.org/article/809567b7872d46839055248de5bec43e
Autor:
Aakash Varun Chhibber, Philip C Hill, James Jafali, Momodou Jasseh, Mohammad Ilias Hossain, Malick Ndiaye, Jayani C Pathirana, Brian Greenwood, Grant A Mackenzie
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137095 (2015)
OBJECTIVE:To measure mortality and its risk factors among children discharged from a health centre in rural Gambia. METHODS:We conducted a cohort study between 12 May 2008 and 11 May 2012. Children aged 2-59 months, admitted with suspected pneumonia,
Externí odkaz:
https://doaj.org/article/804699138de74e90876326d8e244e5cf
Autor:
Jacek Skarbinski, Dyson Mwandama, Madalitso Luka, James Jafali, Adam Wolkon, David Townes, Carl Campbell, John Zoya, Doreen Ali, Don P Mathanga
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21995 (2011)
High levels of insecticide treated bednet (ITN) use reduce malaria burden in countries with intense transmission such as Malawi. Since 2007 Malawi has implemented free health facility-based ITN distribution for pregnant women and children
Externí odkaz:
https://doaj.org/article/8e0a11c4713748e38a7c53590be68299
Autor:
Sarah E Burr, Sally Milne, James Jafali, Ebrima Bojang, Megha Rajasekhar, John Hart, Emma M Harding-Esch, Martin J Holland, David CW Mabey, Ansumana Sillah, Robin L Bailey, Anna Roca
Publikováno v:
Bulletin of the World Health Organization, Vol 92, Iss 7, Pp 490-498
Objective To evaluate the effect of repeated mass drug administration (MDA) of azithromycin in the Gambia on the nasopharyngeal carriage of Streptococcus pneumoniae and on the emergence of antibiotic-resistant strains. Methods This study involved vil
Externí odkaz:
https://doaj.org/article/0cbdca96a79c41ca912c2d718f20efa8
Autor:
Raphael Kamng'ona, Ben Morton, Charlotte van der Veer, Grace Katha, Kelvin Mponda, James Nyirenda, Paul Kambiya, Catherine Anscombe, Jennifer E. Cornick, Kayla G. Barnes, Chimota Phiri, Prisca Matambo, Henry C. Mwandumba, Khuzwayo C. Jere, Jane Mallewa, Mulinda Nyirenda, Comfort Brown, Kwazizira Samson Mndolo, Jonathan Mandolo, Tamara Phiri, James Jafali, Jamie Rylance, Kondwani C. Jambo, Stephen B. Gordon, Ndaziona Peter Banda
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
NATURE COMMUNICATIONS
NATURE COMMUNICATIONS
Although the COVID-19 pandemic has left no country untouched there has been limited research to understand clinical and immunological responses in African populations. Here we characterise patients hospitalised with suspected (PCR-negative/IgG-positi
Autor:
Emile R. Chimusa, Funmilayo Makinde, Milaine S S Tchamga, Gaston K. Mazandu, Segun Fatumo, James Jafali, Nicola Mulder
Publikováno v:
Brief Bioinform
Over the past few years, meta-analysis has become popular among biomedical researchers for detecting biomarkers across multiple cohort studies with increased predictive power. Combining datasets from different sources increases sample size, thus over