Zobrazeno 1 - 9
of 9
pro vyhledávání: '"James J. Spelman"'
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figures 5-7 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5550a69979710e76b33bf0c32049758a
https://doi.org/10.1158/0008-5472.22383065
https://doi.org/10.1158/0008-5472.22383065
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figure 8 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1f22fa15aad5f236df43c06c726794
https://doi.org/10.1158/0008-5472.22383071
https://doi.org/10.1158/0008-5472.22383071
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Methods, Figure and Table Legends from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0800f85e6a3c750e356d1153687ea4d6
https://doi.org/10.1158/0008-5472.22383062.v1
https://doi.org/10.1158/0008-5472.22383062.v1
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Multiple pathways have been proposed to explain how proteasome inhibition induces cell death, but mechanisms remain unclear. To approach this issue, we performed a genome-wide siRNA screen to evaluate the genetic determinants that confer sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::447f83f4a5ac4ed58b1abc343d56192c
https://doi.org/10.1158/0008-5472.c.6500411
https://doi.org/10.1158/0008-5472.c.6500411
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Figures 1-4 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::176e6d9a80ab572faac33eb8592ee188
https://doi.org/10.1158/0008-5472.22383068.v1
https://doi.org/10.1158/0008-5472.22383068.v1
Autor:
Eric S. Lightcap, Jay P. Morgenstern, James J. Spelman, Claudia Rabino, John Ringeling, Patrick J. Leroy, Paul Hales, Jesse Gray, Darshan S. Sappal, Khristofer Garcia, Wei Chen, Anne L. Burkhardt, Trupti Lingaraj, Denise L. Driscoll, Jie Yu, Saurabh Menon, Michael D. Pickard, David M. Rappoli, Xiaozhen J. Liu, Theodore Peters, Jonathan L. Blank, Siquan Chen
Supplementary Table 3A-F from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7456024411b7d0d4b05c26bd9685064b
https://doi.org/10.1158/0008-5472.22383059.v1
https://doi.org/10.1158/0008-5472.22383059.v1
Autor:
Paul Hales, Saurabh Menon, Theodore Peters, Claudia Rabino, Khristofer Garcia, Jesse Gray, John Ringeling, Anne L. Burkhardt, Patrick J. LeRoy, Siquan Chen, Jay P. Morgenstern, Jonathan L. Blank, Wei Chen, Trupti Lingaraj, Darshan S. Sappal, Michael D. Pickard, Jie Yu, David M. Rappoli, Eric S. Lightcap, Xiaozhen J. Liu, Denise L. Driscoll, James J. Spelman
Publikováno v:
Cancer Research. 70:4318-4326
Multiple pathways have been proposed to explain how proteasome inhibition induces cell death, but mechanisms remain unclear. To approach this issue, we performed a genome-wide siRNA screen to evaluate the genetic determinants that confer sensitivity
Autor:
Anne L. Burkhardt, Michael Milhollen, Xiaofeng Yang, Huay-Keng Loke, Lawrence R. Dick, Teresa A. Soucy, Irache Visiers, Frank J. Bruzzese, Michael D. Sintchak, James J. Spelman, Steven P. Langston, Ping Li, Kristin B. Hamman, James M. Gavin, Joseph B. Bolen, Nancy Bump, Sells Todd B, Jingya Ma, Christopher F. Claiborne, Stepan Vyskocil, Courtney Cullis, Hua Liao, Mark Rolfe, Dongyun Wu, James E. Brownell, Trupti Lingaraj, William D. Mallender
Publikováno v:
Molecular cell. 37(1)
The NEDD8-activating enzyme (NAE) initiates a protein homeostatic pathway essential for cancer cell growth and survival. MLN4924 is a selective inhibitor of NAE currently in clinical trials for the treatment of cancer. Here, we show that MLN4924 is a
Autor:
Trupti Lingaraj, Darshan S. Sappal, Jie Yu, Claudia Rabino, Wei Chen, Jonathan L. Blank, Paul Hales, Jay P. Morgenstern, Eric S. Lightcap, Jesse Gray, Saurabh Menon, Anne L. Burkhardt, Patrick J. LeRoy, David M. Rappoli, Michael D. Pickard, Jane Liu, Denise L. Driscoll, James J. Spelman, Theodore Peters, Khristofer Garcia, John Ringeling, Siquan Chen
Publikováno v:
Molecular Cancer Therapeutics. 8:A70-A70
Multiple pathways have been proposed as the mechanism by which proteasome inhibition induces cell death. To clarify their relative importance, we performed a genome-wide siRNA screen to evaluate the genetic determinants that confer sensitivity of the