Zobrazeno 1 - 10
of 31
pro vyhledávání: '"James J. Mcgarrigle"'
Autor:
Chun-Chieh Yeh, Ling-Jia Wang, James J. Mcgarrigle, Yong Wang, Chien-Chang Liao, Mustafa Omami, Arshad Khan, Mohammad Nourmohammadzadeh, Joshua Mendoza-Elias, Benjamin Mccracken, Enza Marchese, Barbara Barbaro, Jose Oberholzer
Publikováno v:
Cell Transplantation, Vol 26 (2017)
This study investigates manufacturing procedures that affect islet isolation outcomes from donor pancreata standardized by the North American Islet Donor Score (NAIDS). Islet isolations performed at the University of Illinois, Chicago, from pancreata
Externí odkaz:
https://doaj.org/article/c1abcafccc894152a5d0f2eec07426c1
Autor:
Hok Hei Tam, Daniel G. Anderson, Dale L. Greiner, Hye Jung Han, Marissa Griffin, Katy N. Olafson, Robert Langer, Peter Müller, James J. McGarrigle, Adam Graham, Shady Farah, Piotr S. Kowalski, Joshua C. Doloff, Jose Oberholzer, Jennifer Hollister-Lock, Ashley Meng, Malia McAvoy, Keval Vyas, Gordon C. Weir, Atieh Sadraei
Publikováno v:
Nature materials
Implantable medical devices have revolutionized modern medicine. However, immune-mediated foreign body response (FBR) to the materials of these devices can limit their function or even induce failure. Here we describe long-term controlled-release for
Autor:
Joshua E. Mendoza-Elias, Yi He, Jose Oberholzer, Enza Marchese, Matthew A. Bochenek, Meirigeng Qi, Yuan Xing, Yong Wang, James J. McGarrigle
Publikováno v:
Pancreas. 49(5)
Objectives Previously, we showed that diazoxide (DZ), an effective ischemic preconditioning agent, protected rodent pancreas against ischemia-reperfusion injury. Here, we further investigate whether DZ supplementation to University of Wisconsin (UW)
Autor:
Filip Rázga, Dusan Chorvat, Michal Pelach, Zuzana Kroneková, Jose Oberholzer, Veronika Némethová, Szabolcs Szalai, Vladimír Raus, Petra Mazancová, Eva Majkova, Lucia Uhelská, Igor Lacík, Sofia Ghani, James J. McGarrigle, Peter Siffalovic, Douglas Isa, Mustafa Omami, Dušana Treľová
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
A next-generation cure for type 1 diabetes relies on immunoprotection of insulin-producing cells, which can be achieved by their encapsulation in microspheres made of non-covalently crosslinked hydrogels. Treatment success is directly related to the
Autor:
Jose Oberholzer, Daniel G. Anderson, Douglas Isa, Bo-Ru Yang, Hui jiuan Chen, Hok Hei Tam, Ira Joshi, Volkan Yesilyurt, Arturo J. Vegas, Jun Tao, Joshua C. Doloff, Weiheng Wang, Jie Li, Xi Xie, Sofia Ghani, Mustafa Omami, Andrew Bader, Robert Langer, Shady Farah, Omid Veiseh, James J. McGarrigle, Katrina Ann Williamson, Atieh Sadraei
Publikováno v:
Nature biomedical engineering
Continuous glucose monitors (CGMs), used by patients with diabetes mellitus, can autonomously track fluctuations in blood glucose over time. However, the signal produced by CGMs during the initial recording period following sensor implantation contai
Autor:
Matthew A, Bochenek, Omid, Veiseh, Arturo J, Vegas, James J, McGarrigle, Meirigeng, Qi, Enza, Marchese, Mustafa, Omami, Joshua C, Doloff, Joshua, Mendoza-Elias, Mohammad, Nourmohammadzadeh, Arshad, Khan, Chun-Chieh, Yeh, Yuan, Xing, Douglas, Isa, Sofia, Ghani, Jie, Li, Casey, Landry, Andrew R, Bader, Karsten, Olejnik, Michael, Chen, Jennifer, Hollister-Lock, Yong, Wang, Dale L, Greiner, Gordon C, Weir, Berit Løkensgard, Strand, Anne Mari A, Rokstad, Igor, Lacik, Robert, Langer, Daniel G, Anderson, Jose, Oberholzer
Publikováno v:
Nature biomedical engineering. 2(11)
The transplantation of pancreatic islet cells could restore glycaemic control in patients with type-I diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic control in diabetic rodent models; yet human patients transplanted w
Autor:
Enza Marchese, James J. McGarrigle, Jose Oberholzer, Jin Wuk Lee, Yuan Xing, Matthew A. Bochenek, Mohammad Nourmohammadzadeh, David T. Eddington, Yong Wang, Yeh Chun-Chieh, Joshua E. Mendoza-Elias
Publikováno v:
Lab on a Chip. 16:1466-1472
In this study, we present a microfluidic array for high resolution imaging of individual pancreatic islets. The device is based on hydrodynamic trapping principles and enables real-time analysis of islet cellular responses to insulin secretagogues. T
Autor:
Dale L. Greiner, Siddharth Jhunjhunwala, Joshua C. Doloff, Felicia W. Pagliuca, Jie Li, Arturo J. Vegas, Jeffrey R. Millman, Srujan Gandham, Hok Hei Tam, Daniel G. Anderson, Mads Gürtler, Michael Chen, Gordon C. Weir, Douglas A. Melton, Jose Oberholzer, Andrew Bader, Omid Veiseh, Jennifer Hollister-Lock, Robert Langer, Karsten Olejnik, Matthew A. Bochenek, Erin Langan, James J. McGarrigle, Stephanie Aresta-Dasilva
Publikováno v:
Nature medicine
The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control in individuals with diabetes. Pancreas transplantation and the infusion of cadaveric islets are currently implemented clinically, b
Autor:
Enza Marchese, Yuan Xing, Mustafa Omami, Michael Chen, Omid Veiseh, Karsten Olejnik, Gordon C. Weir, Jose Oberholzer, Matthew A. Bochenek, Joshua E. Mendoza-Elias, Daniel G. Anderson, Arturo J. Vegas, Dale L. Greiner, Joshua C. Doloff, Mohammad Nourmohammadzadeh, Andrew Bader, Douglas Isa, James J. McGarrigle, Berit L. Strand, Robert Langer, Arshad Khan, Jennifer Hollister-Lock, Casey E. Landry, Meirigeng Qi, Jie Li, Igor Lacík, Sofia Ghani, Anne Mari Rokstad, Yong Wang, Chun Chieh Yeh
Publikováno v:
PMC
The transplantation of pancreatic islet cells could restore glycaemic control in patients with type 1 diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic control in rodent models of diabetes; however, humans transplanted w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aad2e64a0b1edbac2208d7813421434
https://hdl.handle.net/1721.1/121978
https://hdl.handle.net/1721.1/121978
Autor:
Matthew A. Bochenek, Mick Reedy, Sofia Ghani, Ira Joshi, Enza Marchese, Yong Wang, Mustafa Omami, Yuan Xing, Jose Oberholzer, Maha Longi, James J. McGarrigle, Douglas Isa
Publikováno v:
Current Diabetes Reports. 17
Type 1 diabetes mellitus (T1DM) is an autoimmune disease that results from the destruction of insulin-producing pancreatic β cells in the islets of Langerhans. Islet cell transplantation has become a successful therapy for specific patients with T1D