Zobrazeno 1 - 10
of 45
pro vyhledávání: '"James J. McDermott"'
Autor:
Jacob B. Pierce, Muthiah Vaduganathan, Gregg C. Fonarow, Uchechukwu Ikeaba, Karen Chiswell, Javed Butler, Adam D. DeVore, Paul A. Heidenreich, Joanna C. Huang, Michelle M. Kittleson, Karen E. Joynt Maddox, Karthik K. Linganathan, James J. McDermott, Anjali Tiku Owens, Pamela N. Peterson, Scott D. Solomon, Orly Vardeny, Clyde W. Yancy, Stephen J. Greene
Publikováno v:
JAMA Cardiology.
ImportanceClinical guidelines for patients with heart failure with reduced ejection fraction (HFrEF) strongly recommend treatment with a sodium-glucose cotransporter-2 inhibitor (SGLT2i) to reduce cardiovascular mortality or HF hospitalization. Natio
Autor:
Su Ern Yeoh, Joanna Osmanska, Mark C Petrie, Katriona J M Brooksbank, Andrew L Clark, Kieran F Docherty, Paul W X Foley, Kaushik Guha, Crawford A Halliday, Pardeep S Jhund, Paul R Kalra, Gemma McKinley, Ninian N Lang, Matthew M Y Lee, Alex McConnachie, James J McDermott, Elke Platz, Peter Sartipy, Alison Seed, Bethany Stanley, Robin A P Weir, Paul Welsh, John J V McMurray, Ross T Campbell
Publikováno v:
European Heart Journal.
Background and Aims To examine the decongestive effect of the sodium-glucose cotransporter 2 inhibitor dapagliflozin compared to the thiazide-like diuretic metolazone in patients hospitalized for heart failure and resistant to treatment with intraven
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209713 (2018)
Pentatricopeptide repeat (PPR) proteins are helical repeat proteins that bind specific RNA sequences via modular 1-repeat:1-nucleotide interactions. Binding specificity is dictated, in part, by hydrogen bonds between the amino acids at two positions
Externí odkaz:
https://doaj.org/article/3470a3e28d8b4b0c9642d2ffed0c66ed
Autor:
Adam D. DeVore, Nicole Solomon, Paul A. Heidenreich, Anjali T. Owens, Muthiah Vaduganathan, James J McDermott, Clyde W. Yancy, Shuaiqi Zhang, Pamela N. Peterson, Michelle M. Kittleson, Stephen J. Greene, Orly Vardeny, Karen E. Joynt Maddox, Gregg C. Fonarow, Javed Butler, Scott D. Solomon, Karen Chiswell, Joanna C. Huang
Publikováno v:
Journal of cardiac failure. 28(4)
The sodium-glucose cotransporter-2 (SGLT-2) inhibitors form the latest pillar in the management of heart failure with reduced ejection fraction (HFrEF) and appear to be effective across a range of patient profiles. There is increasing interest in ini
Publikováno v:
The Plant Cell. 31:1723-1733
Pentatricopeptide repeat (PPR) proteins bind RNA via a mechanism that facilitates the customization of sequence specificity. However, natural PPR proteins have irregular features that limit the degree to which their specificity can be predicted and c
Autor:
Brooke Alhanti, Stephen J. Greene, James J McDermott, Karen E. Joynt Maddox, Paul A. Heidenreich, Pamela N. Peterson, Shuaiqi Zhang, Muthiah Vaduganathan, Gregg C. Fonarow, Michelle M. Kittleson, Javed Butler, Anjali T. Owens, Scott D. Solomon, Adam D. DeVore, Clyde W. Yancy, Orly Vardeny, Ravi B. Patel, Joanna C. Huang
Publikováno v:
Journal of the American College of Cardiology. 78(4)
Background Few contemporary data exist evaluating care patterns and outcomes in heart failure (HF) across the spectrum of kidney function. Objectives This study sought to characterize differences in quality of care and outcomes in patients hospitaliz
Autor:
Pamela N. Peterson, Michelle M. Kittleson, Javed Butler, Scott D. Solomon, Muthiah Vaduganathan, Paul A. Heidenreich, Clyde W. Yancy, Stephen J. Greene, Shuaiqi Zhang, Maria V. Grau-Sepulveda, Orly Vardeny, Gregg C. Fonarow, Anjali T. Owens, Karen E. Joynt Maddox, Joanna C. Huang, James J McDermott, Adam D. DeVore
Publikováno v:
JAMA Cardiol
IMPORTANCE: In May 2020, dapagliflozin was approved by the US Food and Drug Administration (FDA) as the first sodium-glucose cotransporter 2 inhibitor for heart failure with reduced ejection fraction (HFrEF), based on the Dapagliflozin and Prevention
Autor:
Bernhard H. Weigl, Tim C. Chang, James J McDermott, Caitlin E Anderson, Toan Huynh, Ciela I. Oncina, Samantha A. Byrnes, Kevin P. Nichols
Publikováno v:
Analytical chemistry. 92(5)
Immunoassays are important for the detection of proteins to enable disease identification and monitor treatment, but many immunoassays suffer from sensitivity limitations. The development of digital assays has enabled highly sensitive biomarker detec
Publikováno v:
Nucleic Acids Research
Pentatricopeptide repeat (PPR) proteins are helical-repeat proteins that offer a promising scaffold for the engineering of proteins to bind specified RNAs. PPR tracts bind RNA in a modular 1-repeat, 1-nucleotide fashion. An amino acid code specifying
Publikováno v:
Chemical Science. 6:294-300
Hydrogen sulfide (H2S) has emerged as an important biological signaling molecule in the last decade. During the growth of this field, significant controversy has arisen centered on the physiological concentrations of H2S. Recently, a monobromobimane