Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James J. M. Cooper"'
Autor:
James J. M. Cooper, Jessie J. Polanco, Darpan Saraswat, Jennifer J. Peirick, Anna Seidl, Yi Li, Dan Ma, Fraser J. Sim
Publikováno v:
Glia. 71:1018-1035
The failure of remyelination in the human CNS contributes to axonal injury and disease progression in multiple sclerosis (MS). In contrast to regions of chronic demyelination in the human brain, remyelination in murine models is preceded by abundant
Autor:
James J. M. Cooper, Stephanie Newman, Stephanie Egan, Adam Utley, Kelvin P. Lee, Joseph J. Barbi
Publikováno v:
The Journal of Immunology. 200:107.6-107.6
T Regulatory cells (Tregs) are critical mediators of the immune system both during active immune responses and in the maintenance of immune homeostasis. Neuritin, a highly conserved gpi-anchored protein, has been shown to regulate Treg maintenance an
Autor:
Adam Utley, James J. M. Cooper, Colin A. Chavel, Peng Peng, Louise M. Carlson, Shivana M. Lightman, Taku Kambayashi, Jonathan Green, Kelvin P. Lee
Publikováno v:
The Journal of Immunology. 200:51.2-51.2
Durable humoral immunity depends upon bone marrow resident long-lived plasma cell (LLPC) survival. We have shown that CD28, the canonical T-cell costimulatory molecule, is required for LLPC survival; however, the mechanistic basis for this is unclear
Autor:
James J. M. Cooper, Adam Utley, Peng Peng, Amin Mahpour, Louise M Carlson, Sigrid A Carle, Kelvin P Lee
Publikováno v:
The Journal of Immunology. 198:144.5-144.5
Durable humoral immunity is dependent upon sustained antibody production by long-lived plasma cells (LLPCs). We have published that CD28 is required for LLPC survival and antibody production in vivo; however, the mechanistic basis for this is unclear