Zobrazeno 1 - 10
of 15
pro vyhledávání: '"James J. Hobson"'
Autor:
Paul Curley, James J. Hobson, Neill J. Liptrott, Edward Makarov, Amer Al-khouja, Lee Tatham, Christopher A. W. David, Helen Box, Megan Neary, Joanne Sharp, Henry Pertinez, David Meyers, Charles Flexner, Caren L. Freel Meyers, Larisa Poluektova, Steve Rannard, Andrew Owen
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 1835 (2023)
Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported h
Externí odkaz:
https://doaj.org/article/30c9897dc2e441029b763227a146a61d
Autor:
James J. Hobson, Amer Al-khouja, Paul Curley, David Meyers, Charles Flexner, Marco Siccardi, Andrew Owen, Caren Freel Meyers, Steve P. Rannard
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Non-adherence to daily drug regimens is responsible for many negative clinical effects including drug resistance in life-long treatments for HIV. Here, the authors report on a HIV prodrug nanoparticle platform for long-acting sustained release of wat
Externí odkaz:
https://doaj.org/article/0af90520fd9449aa84b2d09b2855e9b8
Autor:
Owen, Paul Curley, James J. Hobson, Neill J. Liptrott, Edward Makarov, Amer Al-khouja, Lee Tatham, Christopher A. W. David, Helen Box, Megan Neary, Joanne Sharp, Henry Pertinez, David Meyers, Charles Flexner, Caren L. Freel Meyers, Larisa Poluektova, Steve Rannard, Andrew
Publikováno v:
Pharmaceutics; Volume 15; Issue 7; Pages: 1835
Long-acting injectable (LAI) formulations promise to deliver patient benefits by overcoming issues associated with non-adherence. A preclinical assessment of semi-solid prodrug nanoparticle (SSPN) LAI formulations of emtricitabine (FTC) is reported h
Autor:
Frank McCaughan, Lee Tatham, Joanne Herriott, Steve P. Rannard, Kevin Dhaliwal, Edyta Kijak, James P. Stewart, Henry Pertinez, Joanne Sharp, Anja Kipar, James J. Hobson, Paul Curley, Andrew Owen, Helen Box, Usman Arshad, Anthony Valentijn, Rajith K. R. Rajoli, Megan Neary
Publikováno v:
bioRxiv
Successful development of a chemoprophylaxis against SARS-CoV-2 could provide a tool for infection prevention implementable alongside vaccination programmes. Camostat and nafamostat are serine protease inhibitors that inhibit SARS-CoV-2 viral entry i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::188bacb060485772071766ba5cdf2335
https://doi.org/10.1101/2021.07.08.451654
https://doi.org/10.1101/2021.07.08.451654
Autor:
Marco Siccardi, Paul Curley, Steve P. Rannard, Andrew Owen, Alison C. Savage, James J. Hobson, Charles Flexner, Amer Al-khouja, Caren L. Freel Meyers
Publikováno v:
Nanoscale Advances. 1:4301-4307
The facile formation of drug nanoparticles in injectable/ingestible oils, of water-soluble antiretroviral tenofovir disoproxil fumarate, using a novel nanoprecipitation is presented with studies showing drug release into relevant aqueous media.
Autor:
James J. Hobson, Paul Curley, A. B. Dwyer, Usman Arshad, Helen Box, Andrew Owen, Henry Pertinez, Christopher David, Tom O. McDonald, Neill J. Liptrott, Jonathan Massam, Alison C. Savage, Joanne Sharp, Steve P. Rannard, Rajith K. R. Rajoli, Megan Neary, Anthony Valentijn, Catherine Unsworth, Lee Tatham
Publikováno v:
Nanoscale. 13(13)
The control of COVID-19 across the world requires the formation of a range of interventions including vaccines to elicit an immune response and immunomodulatory or antiviral therapeutics. Here, we demonstrate the nanoparticle formulation of a highly
Autor:
Steve P. Rannard, James J. Hobson, Sean Flynn, Pierre Chambon, Helen Cauldbeck, Stephanie E. Edwards
Publikováno v:
RSC ADVANCES
Mucus lines the moist cavities throughout the body, acting as barrier by protecting the underlying cells against the external environment, but it also hinders the permeation of drugs and drug delivery systems. As the rate of diffusion is low, the dev
Publikováno v:
Nanomedicine
Aim: A preclinical safety assessment of a novel nanoemulsion drug-delivery system, initially developed to improve the posology of efavirenz (EFV), was conducted with a specific focus on possible immunological and hematological complications. Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d3abd59f3c0561230a3b3493458964
Publikováno v:
Nanomedicine. 13:1963-1965
Autor:
Paul Curley, Charles Flexner, David J. Meyers, Marco Siccardi, Stephanie Henriquez, Caren L. Freel Meyers, James J. Hobson, Andrew Owen, Amer Al-khouja, Steven Paul Rannard
Publikováno v:
The FASEB Journal. 32