Zobrazeno 1 - 10
of 321
pro vyhledávání: '"James J. Christensen"'
Autor:
Ingrid L. Chen, Rebecca J. Nagy, James J. Christensen, Kimberly C. Banks, Nisha Mohindra, Lindsey Shantzer, Hardeep Phull, Jeffrey M. Clarke, Sandip Pravin Patel, Miriam T. Jacobs, William Mitchell, Jyoti D. Patel, Victoria M. Raymond, Richard B. Lanman
Publikováno v:
JCO Precision Oncology. :1-10
Purpose To evaluate the clinical outcome of patients with non–small-cell lung cancer treated by targeting low variant allelic frequency (VAF) driver mutations identified through cell-free DNA (cfDNA) next-generation sequencing (NGS). Detection of d
Autor:
Laura Waters, Melissa Lynne Johnson, Kavita Garg, Lars D. Engstrom, Mark M. Awad, Pasi A. Jänne, Xiaoping Yang, Sai-Hong Inatius Ou, Mark Li, Andrew J. Aguirre, Gregory J. Riely, Viola W. Zhu, Kathryn C. Arbour, Julien Dilly, David E. Root, Rebecca S. Heist, Nicole S. Persky, Lynette M. Sholl, Lee Lim, J. David Lawson, Piro Lito, Shengwu Liu, Peter D. Olson, Joseph O. Jacobson, Tejas Patil, James J. Christensen
Publikováno v:
Cancer Research. 81:LB002-LB002
Background: KRAS glycine-to-cysteine amino acid substitutions at codon 12 (KRASG12C) occur in ~13% of non-small cell lung cancers (NSCLC), ~3% of colorectal cancers (CRC), and less commonly in other cancer types. In early phase clinical trials of pat
Autor:
W. Lawler, Thian Kheoh, Mark A. Socinski, R. Yanagihara, Marina Chiara Garassino, Pasi A. Jänne, Merrill Kingman Shum, S. Roshan, James J. Christensen, Alexander I. Spira, Richard C. Chao, G. J. Riely
Publikováno v:
Journal of Thoracic Oncology. 16:S696
Autor:
Bolot Mambetsariev, Alex E. Pozhitkov, Lars D. Engstrom, James J. Christensen, Ravi Salgia, Tamara Mirzapoiazova, Jiale Wang, Isa Mambetsariev, Yingyu Wang, Carol Tan, Prakash Kulkarni
Publikováno v:
The FASEB Journal. 32
Autor:
Trevor J. Pugh, Lauren L. Ritterhouse, Khanh T. Do, Geoffrey I. Shapiro, Lynette M. Sholl, William C. Hahn, Frank C. Kuo, Ursula A. Matulonis, Philip W. Kantoff, Paul Van Hummelen, Matthew Meyerson, Ethan Cerami, Bruce E. Johnson, Phani K. Davineni, Richard C. Chao, Neal I. Lindeman, Mizuki Nishino, James M. Cleary, Priyanka Shivdasani, Aaron R. Thorner, Joshua D. Campbell, Barrett J. Rollins, Vanesa Rojas-Rudilla, Geoffrey R. Oxnard, Adrian M. Dubuc, Marian H. Harris, Levi A. Garraway, James J. Christensen, David J. Kwiatkowski, Elizabeth P. Garcia, Azra H. Ligon, Laura E. MacConaill, Shakti Ramkissoon, V. Tassell, Alanna J. Church, Yonghui Jia, Alice H. Berger, Ryan P. Abo, Matthew D. Ducar, Katherine A. Janeway
Publikováno v:
JCI Insight. 1
BACKGROUND. Comprehensive genomic profiling of a patient's cancer can be used to diagnose, monitor, and recommend treatment. Clinical implementation of tumor profiling in an enterprise-wide, unselected cancer patient population has yet to be reported
Autor:
Melissa Lynne Johnson, Demiana Faltaos, James J. Christensen, Karen Velastegui, Kyriakos P. Papadopoulos, Sai-Hong Ignatius Ou, Diane Potvin, Richard C. Chao
Publikováno v:
Journal of Clinical Oncology. 37:TPS3161-TPS3161
TPS3161 Background: RAS proteins are part of the family of small GTPases which regulate intracellular signaling pathways responsible for cell growth, migration, survival and differentiation. Oncogenic point mutations in RAS in codons 12, 13, and 61 o
Autor:
Delia Alvarez, Luke T. Nordquist, David R. Shaffer, Donald A. Richards, Daniel Chong, Jeffrey Yorio, Joel Picus, Hirak Der-Torossian, James J. Christensen, Nicholas J. Vogelzang, Gurjyot K. Doshi
Publikováno v:
Journal of Clinical Oncology. 37:TPS498-TPS498
TPS498 Background: Combination therapy with agents targeting molecular and cellular mechanisms of CIT resistance is a rational approach to restoring CIT efficacy in patients (pts) with immunotherapy-resistant UC. Sitravatinib is a tyrosine kinase inh
Publikováno v:
Chemical reviews. 74(3)
Autor:
Richard C. Chao, Jong Seok Lee, Frederico Cappuzzo, Estelamari Rodriguez, Pasi A. Jänne, Demiana Faltaos, Byoung Chul Cho, David S. Hong, Raul Mena, Ji-Youn Han, V. Tassell, Hoon-Kyo Kim, James J. Christensen, Marshall T. Schreeder, Ashiq Masood, Dong Wan Kim, Igor I. Rybkin, Diane Potvin, Lyudmila Bazhenova, Melissa Lynne Johnson, Ranee Mehra, Britt Boleman, Luigi Cavanna, Marta Batus, Hirak Der-Torossian, Ivor John Percent
Publikováno v:
Journal of Thoracic Oncology. 12:S1080-S1081
Autor:
Nisha Mohindra, John Nemunaitis, Missak Haigentz, Keith D. Eaton, Manish R. Patel, James J. Christensen, Diane Potvin, Edward B. Garon, Demiana Faltaos, Mark M. Awad, Matteo Levisetti, Isan Chen, Melissa Lynne Johnson, Tavette Neskorik
Publikováno v:
Journal of Thoracic Oncology. 12:S1073-S1074