Zobrazeno 1 - 10
of 11
pro vyhledávání: '"James J. Carlo"'
Autor:
Gladys Ekman, Gregory Pincus, Wilson R. Slaunwhite, Lewis L. Engel, James J. Carlo, Ira T. Nathanson
Publikováno v:
Acta Endocrinologica. 7:321-329
Publikováno v:
Steroids. 5:327-336
When progesterone-4-14C, 2.2–2.4 × 10−4M, was perfused through cow adrenal glands for 10 cycles in the presence of Metopirone, 1.1 × 10−4M, the substances isolated included 11-deoxycortisol (18.5% and 22.6% conversion) and deoxycorticosterone
Publikováno v:
Steroids. 5:337-344
Publikováno v:
Steroids. 5:147-162
Deoxycorticosterone (DOC), 125 mg/l, 3.8 × 10−4 M, in bovine blood was perfused, through bovine adrenal glands in the presence of a varying amount of Metopirone (100-3.15 mg/l, 4.4−0.14 × 10−4M) and for a varying number of cycles (5–35) to
Publikováno v:
Steroids. 5:479-493
Androst-4-en-3,17-dione-4-14C, 350 μM, was perfused through cow adrenals for 5–6 and 30 cycles in the absence of Metopirone and in its presence at 110 μM and 55 μM. Hydroxylations at 11β and 19, the chief reactions in the unmodified perfusion,
Publikováno v:
Steroids. 5:677-686
17β-Estradiol-4-14C was perfused through bovine adrenal glands. The bulk (65%) of the estradiol was recovered, but several metabolites, all in low rates of conversion, were isolated. Four of these were identified as esterone, estriol, 16β-epiestrio
Publikováno v:
Steroids. 5:131-146
The nature of the substances formed from deoxycorticosterone in bovine adrenal perfusion has been reinvestlgated. In addition to corticosterone, the following substances were isolated in crystalline form and identified: 11β,21-dihydroxy-5α-pregnan-
Publikováno v:
Steroids. 85
When 11-deoxycortisol, 3.6 × 10−4M, was perfused through cow adrenals for 5 cycles, cortisol (55.0% conversion) and 19-hydroxy-11-deoxycortisol (2.1%) were isolated. No precursor was recovered. When this perfusion was repeated in the presence of M
Publikováno v:
The Journal of clinical endocrinology and metabolism. 8(3)
THE observation that there is a diurnal rhythm in urinary ketosteroid excretion (1, 2, 3) and that this may be related to stress-stimulated adrenocortical secretion (2) led us to examine other possible indices of adrenocortical secretion. The develop
Publikováno v:
Journal of gerontology. 9(2)