Zobrazeno 1 - 10
of 82
pro vyhledávání: '"James J. Lai"'
Autor:
Manuel S. V. Jaimes, Chia‐Te Liao, Max M. Chen, Andreas Czosseck, Tsung‐Lin Lee, Yu‐Hsiang Chou, Yung‐Ming Chen, Shuei‐Liong Lin, James J. Lai, David J. Lundy
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 5, Pp n/a-n/a (2023)
Abstract Calorie restriction (CR) and fasting affect lifespan, disease susceptibility and response to acute injury across multiple animal models, including ischaemic injuries such as myocardial infarction or kidney hypoxia. The cargo and function of
Externí odkaz:
https://doaj.org/article/7423ec3d8ad94608bdc03b76dd6838f6
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Urine is an attractive biospecimen for in vitro diagnostics, and urine-based lateral flow assays are low-cost devices suitable for point-of-care testing, particularly in low-resource settings. However, some of the lateral flow assays exhibit limited
Externí odkaz:
https://doaj.org/article/1df84fc179524378b6864d4752a95938
Autor:
James J. Lai, Zoe L. Chau, Sheng‐You Chen, John J. Hill, Katalin V. Korpany, Nai‐Wen Liang, Li‐Han Lin, Yi‐Hsuan Lin, Joanne K. Liu, Yu‐Chung Liu, Ruby Lunde, Wei‐Ting Shen
Publikováno v:
Advanced Science, Vol 9, Iss 15, Pp n/a-n/a (2022)
Abstract Exosomes are extracellular vesicles that share components of their parent cells and are attractive in biotechnology and biomedical research as potential disease biomarkers as well as therapeutic agents. Crucial to realizing this potential is
Externí odkaz:
https://doaj.org/article/ac9a3853d16d44c6a5175972d47f0920
Autor:
Justin D Vrana, Nuttada Panpradist, Nikki Higa, Daisy Ko, Parker Ruth, Ruth Kanthula, James J Lai, Yaoyu Yang, Samar R Sakr, Bhavna Chohan, Michael H Chung, Lisa M Frenkel, Barry R Lutz, Eric Klavins, Ingrid A Beck
Publikováno v:
PLOS Global Public Health, Vol 2, Iss 2, p e0000185 (2022)
Usability is an overlooked aspect of implementing lab-based assays, particularly novel assays in low-resource-settings. Esoteric instructions can lead to irreproducible test results and patient harm. To address these issues, we developed a software a
Externí odkaz:
https://doaj.org/article/dcdfb395c1bb4ae6a750cadd407f1b57
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Externí odkaz:
https://doaj.org/article/4e51a165284146338059ee4107a9006f
Autor:
Gaurav K. Gulati, Nuttada Panpradist, Samuel W. A. Stewart, Ingrid A. Beck, Ceejay Boyce, Amy K. Oreskovic, Claudia García-Morales, Santiago Avila-Ríos, Peter D. Han, Gustavo Reyes-Terán, Lea M. Starita, Lisa M. Frenkel, Barry R. Lutz, James J. Lai
Publikováno v:
The Analyst. 147:3315-3327
This new workflow enables co-extraction of HIV and SARS-CoV2 RNAs from clinical pooled plasma/nasal secretion samples that allows sensitive detection of SARS-CoV-2 and HIV infections in the patients-living with HIV.
Publikováno v:
ACS Appl Mater Interfaces
Nanoscale coordination polymers are promising vehicles for anticancer drug delivery because their surface composition and particle size can be tuned to exploit the enhanced permeability and retention effect, and their reversible interaction with meta
Publikováno v:
Biomaterials Science. 9:4870-4879
Early diagnosis of infectious diseases is one of the current prevalent challenges, especially in low and limited resource settings where simple, fast, portable, cheap, and sensitive diagnostic approaches are needed. Lateral flow immunoassay (LFIA) is
Autor:
Sheng-Lun Chen, David J. Lundy, Shu-Chian Ruan, Hung-Chih Chen, Yu-Kai Chao, Yuan-Yuan Cheng, Ray Putra Prajnamitra, Chun-Chieh Liao, Chung-Yen Lin, James J. Lai, Patrick C.H. Hsieh
Publikováno v:
Biomaterials. 289
We hypothesized that the host microbiome may influence foreign body responses following biomaterial implantation. To test this, we implanted a variety of clinically relevant biomaterials into germ-free or antibiotic-treated mice. Surprisingly, these
Stimuli-Responsive Polymer-Antibody Conjugates via RAFT and Tetrafluorophenyl Active Ester Chemistry
Publikováno v:
ACS macro letters. 2(2)
Highly efficient polymer-antibody conjugations were demonstrated via a tetrafluorophenyl active ester. A well-defined diblock copolymer was synthesized by reversible addition–fragmentation chain transfer (RAFT) polymerization with a temperature-res