Zobrazeno 1 - 10
of 62
pro vyhledávání: '"James J. Fleming"'
Publikováno v:
Angewandte Chemie. 116:4449-4452
Autor:
Mordecai Rabinovitz, James J. Fleming, Michael R. Mannion, Greg P Manning, Brad L Merner, Ivan Aprahamian, Rudolf J. Vermeij, Tuvia Sheradsky, Graham J. Bodwell
Publikováno v:
Journal of the American Chemical Society. 126:6765-6775
The reduction of a series of [n](2,7)pyrenophanes (n = 7-10) with lithium or potassium metal shows that the strain in the system, controlled by the length of the tether, determines the nature of the reduction products. The reduction of [7](2,7)pyreno
Autor:
Allen J. Bard, James J. Fleming, Graham J. Bodwell, Rebecca Y. Lai, Rudolf J. Vermeij, Brad L. Merner
Publikováno v:
The Journal of Physical Chemistry A. 108:376-383
We report here the photophysical, electrochemical, and electrogenerated chemiluminescent studies of four new pyrenophanes. Comparison with the cyclic voltammogram obtained using the planar parent compound, pyrene, showed these bent-pyrene-containing
Publikováno v:
Tetrahedron. 57:3577-3585
Structures for several mono-, di-, tri- and tetraoxa[7](2,7)pyrenophanes were calculated at the AM1 level of theory and the bend angle ( θ ) of the pyrene system was found to be affected by both the number and the position(s) of the oxygen atom(s).
Publikováno v:
The Journal of Organic Chemistry. 65:5360-5370
A new strategy for the synthesis of Buckybowls is presented and initial attempts to implement it are reported. This involves annulation of further rings onto polycyclic aromatic systems that prefer to be planar but have been “pre-bent” by the ins
Autor:
Pamela M. England, James J. Fleming
Publikováno v:
Nature chemical biology. 6(2)
The ability of the mammalian brain to undergo experience-based adaptations is among its most important and fascinating properties. Such plasticity is reflected in the capacity of neuronal activity to continuously modify the neural circuitry that unde
Autor:
James J. Fleming, Pamela M. England
Publikováno v:
Bioorganicmedicinal chemistry. 18(4)
AMPA receptors are a family of ligand-gated ion channels that play central roles in rapid neural signaling and in regulation of synaptic strength. Additionally, these receptors are implicated in a number of major psychiatric and neurological diseases
Publikováno v:
Journal of the American Chemical Society. 129(32)
A stereoselective synthesis of the bis-guanidinium toxin (+)-saxitoxin (STX), the agent infamously associated with red tides and paralytic shellfish poisoning, is described. Our approach to this unique natural product advances through an unusual nine
Autor:
James J. Fleming, J. Du Bois
Publikováno v:
Journal of the American Chemical Society. 128(12)
An asymmetric synthesis of the bis-guanidinium poison, (+)-saxitoxin (STX), is described. Commencing from an N,O-acetal starting material made readily available through sulfamate ester C−H amination, the completed route to STX showcases the utility
Autor:
Ivan Aprahamian, Graham J. Bodwell, Mordecai Rabinovitz, James J. Fleming, Rudolf J. Vermeij, Michael R. Mannion, Tuvia Sheradsky, Gregory P. Manning
Publikováno v:
Angewandte Chemie (International ed. in English). 42(22)
The reduction of polycyclic aromatic hydrocarbons (PAHs) with alkali metals can, in some cases, afford a reductive dimerization process. This process takes place in systems that have the capability of forming a stable anionic subunit and concentratin