Zobrazeno 1 - 10
of 13
pro vyhledávání: '"James J Richey"'
Autor:
Vienna E. Brunt, Nathan T. Greenberg, Zachary J. Sapinsley, Abigail G. Casso, James J. Richey, Nicholas S. VanDongen, Rachel A. Gioscia-Ryan, Brian P. Ziemba, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals
Publikováno v:
Journal of Applied Physiology. 133:798-813
We provide novel evidence that increased circulating concentrations of the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO) contribute to vascular dysfunction associated with consumption of a Western-style diet and that this dysfunctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54ba50b7ff3f131cfd29cc724131abcd
https://doi.org/10.1152/japplphysiol.00350.2022
https://doi.org/10.1152/japplphysiol.00350.2022
Autor:
Amy E Bazzoni, Andrew P. Neilson, Abigail G. Casso, Vienna E. Brunt, Melanie C. Zigler, Douglas R. Seals, David A. Hutton, James J Richey, Zachary J Sapinsley, Zachary S. Clayton, Kevin P. Davy, Brian P. Ziemba, Nicholas S. VanDongen, Rachel A. Gioscia-Ryan
Publikováno v:
Hypertension. 78:499-511
Aging is associated with stiffening of the large elastic arteries and consequent increases in systolic blood pressure (SBP), which together increase cardiovascular disease risk; however, the upstream mechanisms are incompletely understood. Using comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9e8e35313458aae36f33b041f9179b0
https://doi.org/10.1161/hypertensionaha.120.16895
https://doi.org/10.1161/hypertensionaha.120.16895
Autor:
Rachel A. Gioscia-Ryan, Zachary S. Clayton, Nicholas S. VanDongen, Brian P. Ziemba, Matthew J. Rossman, David A. Hutton, Micah L. Battson, Melanie C. Zigler, James J Richey, Lauren M. Cuevas, Douglas R. Seals
Publikováno v:
J Physiol
KEY POINTS The results of the present study establish the temporal pattern of age-related vascular dysfunction across the adult lifespan in sedentary mice consuming a non-Western diet, and the underlying mechanisms The results demonstrate that consum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15d5aac7d26ad927f417306cf3744ef
https://doi.org/10.1113/jp280607
https://doi.org/10.1113/jp280607
Autor:
Vienna E. Brunt, Andrew P. Neilson, Kevin P. Davy, Douglas R. Seals, Zachary J Sapinsley, Rachel A. Gioscia-Ryan, Brian P. Ziemba, Nicholas S. VanDongen, Abigail G. Casso, Melanie C. Zigler, James J Richey
Publikováno v:
Hypertension. 76:101-112
Age-related vascular endothelial dysfunction is a major antecedent to cardiovascular diseases. We investigated whether increased circulating levels of the gut microbiome-generated metabolite trimethylamine-N-oxide induces endothelial dysfunction with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50587399cfcb0fae280ed912175a44ac
https://doi.org/10.1161/hypertensionaha.120.14759
https://doi.org/10.1161/hypertensionaha.120.14759
Autor:
Melissa R. Mazzo, Douglas R. Seals, Brian P. Ziemba, Sarah A. Johnson, Matthew J. Rossman, Michel Chonchol, Christopher R. Martens, Lindsey R Jankowski, Erzsebet E. Nagy, Yang Wang, Blair A Denman, James J Richey, Courtney M. Peterson
Publikováno v:
GeroScience
Chronic calorie restriction (CR) improves cardiovascular function and several other physiological markers of healthspan. However, CR is impractical in non-obese older humans due to potential loss of lean mass and bone density, poor adherence, and ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2c905f44adb99e19105b7384e1c006
https://europepmc.org/articles/PMC7206473/
https://europepmc.org/articles/PMC7206473/
Autor:
Brian P. Ziemba, Lawrence C. Johnson, Melanie C. Zigler, James J Richey, Rachel Culp-Hill, Rachel A. Gioscia-Ryan, Angelo D'Alessandro, Elan Z. Eisenmesser, Douglas R. Seals, Charles A. Dinarello, Zachary J Sapinsley, Dov B. Ballak, Vienna E. Brunt
Publikováno v:
Aging Cell
Aging is associated with vascular endothelial dysfunction, reduced exercise tolerance, and impaired whole‐body glucose metabolism. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine of the interleukin‐1 family, exerts salutary physiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58dc0240f33d0b4b7246c455ff06ca35
http://europepmc.org/articles/PMC6974720
http://europepmc.org/articles/PMC6974720
Autor:
Matthew J. Rossman, Micah L. Battson, Douglas R. Seals, Melanie C. Zigler, Rachel A. Gioscia-Ryan, James J Richey, Lauren M. Cuevas, Zachary S. Clayton
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82f8157ade2c201fcefa53dd54db50e4
https://doi.org/10.1096/fasebj.2019.33.1_supplement.696.20
https://doi.org/10.1096/fasebj.2019.33.1_supplement.696.20
Autor:
Douglas R. Seals, Yang Wang, Michel Chonchol, Blair A Denman, Lindsey R Jankowski, Christopher R. Martens, Sarah A. Johnson, Matthew J. Rossman, Melissa R. Mazzo, Courtney M. Peterson, Erzsebet E. Nagy, James J Richey
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3821e5483231a75535ff422c9134d10
https://doi.org/10.1096/fasebj.2019.33.1_supplement.590.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.590.2
Autor:
Zachary J Sapinsley, Nicholas S. VanDongen, Andrew P. Neilson, Chris J. Angiletta, Rachel A. Gioscia-Ryan, James J Richey, Abigail G. Casso, Laura E. Griffin, Melanie C. Zigler, Vienna E. Brunt, Douglas R. Seals
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba0b1947e0d5b960b89d95fac61f1a6b
https://doi.org/10.1096/fasebj.2019.33.1_supplement.530.3
https://doi.org/10.1096/fasebj.2019.33.1_supplement.530.3
Autor:
Kevin P. Davy, Tiffany L. Weir, Andrew P. Neilson, Gail Ackermann, James J Richey, Lauren M. Cuevas, Douglas R. Seals, Andrew D. Gilley, Vienna E. Brunt, Yoshiki Vázquez-Baeza, Micah L. Battson, Rachel A. Gioscia-Ryan, Rob Knight, Antonio Gonzalez, Melanie C. Zigler, Andrew T. Smithson
Publikováno v:
J Physiol
KEY POINTS: Age‐related arterial dysfunction, characterized by oxidative stress‐ and inflammation‐mediated endothelial dysfunction and arterial stiffening, is the primary risk factor for cardiovascular diseases. To investigate whether age‐rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a442a8ce1bc70b97dff219902b91229
https://europepmc.org/articles/PMC6487935/
https://europepmc.org/articles/PMC6487935/