Zobrazeno 1 - 10
of 31
pro vyhledávání: '"James IB"'
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Background The adult intestinal epithelium is a complex, self-renewing tissue composed of specialized cell types with diverse functions. Intestinal stem cells (ISCs) located at the bottom of crypts, where they divide to either self-renew, or
Externí odkaz:
https://doaj.org/article/448371cac9694777a9530ddc50b06c00
Autor:
Jeremie Oliver Piña, Resmi Raju, Daniela M. Roth, Emma Wentworth Winchester, Parna Chattaraj, Fahad Kidwai, Fabio R. Faucz, James Iben, Apratim Mitra, Kiersten Campbell, Gus Fridell, Caroline Esnault, Justin L. Cotney, Ryan K. Dale, Rena N. D’Souza
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The terminal differentiation of osteoblasts and subsequent formation of bone marks an important phase in palate development that leads to the separation of the oral and nasal cavities. While the morphogenetic events preceding palatal osteoge
Externí odkaz:
https://doaj.org/article/6f572a2594494ecc86d33a6364a1b88c
Autor:
Resmi Raju, Jeremie Oliver Piña, Daniela M. Roth, Parna Chattaraj, Fahad K. Kidwai, Fabio R. Faucz, James Iben, Gus Fridell, Ryan K. Dale, Rena N. D’Souza
Publikováno v:
Frontiers in Physiology, Vol 14 (2024)
Mouse and human genetic studies indicate key roles of the Wnt10a ligand in odontogenesis. Previous studies have identified effectors and regulators of the Wnt signaling pathway actively expressed during key stages of tooth morphogenesis. However, lim
Externí odkaz:
https://doaj.org/article/a958e080d3da4bdbbc6f230acc3bb8b6
Autor:
Michelle Bloyd, Ninet Sinaii, Fabio Rueda Faucz, James Iben, Steven L. Coon, Sonia Caprio, Nicola Santoro, Constantine A. Stratakis, Edra London
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionPediatric obesity has steadily increased in recent decades. Large-scale genome-wide association studies (GWAS) conducted primarily in Eurocentric adult populations have identified approximately 100 loci that predispose to obesity and type
Externí odkaz:
https://doaj.org/article/3c73aefed5704116b3d0233a2c31eb5f
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Locusts depend upon their sense of smell and provide useful models for understanding olfaction. Extending this understanding requires knowledge of the molecular and structural organization of the olfactory system. Odor sensing begins with ol
Externí odkaz:
https://doaj.org/article/6d7168378d08424c883797667ab9fffd
Autor:
Charles Warwick, Joseph Salsovic, Junichi Hachisuka, Kelly M. Smith, Tayler D. Sheahan, Haichao Chen, James Ibinson, H. Richard Koerber, Sarah E. Ross
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Altered mechanosensation by application of capsaicin to the skin is thought to be spinally mediated. Here, the authors use Ca2+ imaging in spinal neurons and develop a cell profiling approach to identify populations involved in central sensitization.
Externí odkaz:
https://doaj.org/article/80ac351424da470497cb041b61dfcedc
Autor:
Hoda Zarkoob, Anna Allué-Guardia, Yu-Chi Chen, Andreu Garcia-Vilanova, Olive Jung, Steven Coon, Min Jae Song, Jun-Gyu Park, Fatai Oladunni, Jesse Miller, Yen-Ting Tung, Ivan Kosik, David Schultz, James Iben, Tianwei Li, Jiaqi Fu, Forbes D. Porter, Jonathan Yewdell, Luis Martinez-Sobrido, Sara Cherry, Jordi B. Torrelles, Marc Ferrer, Emily M. Lee
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
Human alveolar and tracheobronchial epithelial air liquid interface (ALI) tissues are used as models to examine cellular responses to SARS-CoV-2 and influenza A virus infections and as antiviral drug screening assay platforms.
Externí odkaz:
https://doaj.org/article/003ca60ed064430890c5954d0c4a6343
Autor:
Asif Khalid, Christopher Thomas, Michael Kingsley, Kishore Vipperla, Jeffrey Dueker, Christianna Kreiss, Anna Evans Phillips, Rohit Das, Kenneth Fasanella, James Ibinson
Publikováno v:
Endoscopy International Open, Vol 10, Iss 09, Pp E1188-E1192 (2022)
Background and study aims N95-filtering facepiece respirators (FFR) use is associated with physiological changes and symptoms due to impaired nasal airflow and increased breathing resistance. We prospectively studied the effect of using an external n
Externí odkaz:
https://doaj.org/article/4bfad8d74dd2444ba9063fb14a7a5e1e
Autor:
Ellen Phillips, Naseer Ahmad, Li Sun, James Iben, Christopher J Walkey, Aleksandra Rusin, Tony Yuen, Clifford J Rosen, Ian M Willis, Mone Zaidi, Deborah L Johnson
Publikováno v:
eLife, Vol 11 (2022)
MAF1, a key repressor of RNA polymerase (pol) III-mediated transcription, has been shown to promote mesoderm formation in vitro. Here, we show that MAF1 plays a critical role in regulating osteoblast differentiation and bone mass. Global deletion of
Externí odkaz:
https://doaj.org/article/21c7d77c7c1c4131ace5a7b64a9a61c7
Autor:
Vasilisa Aksenova, Alexandra Smith, Hangnoh Lee, Prasanna Bhat, Caroline Esnault, Shane Chen, James Iben, Ross Kaufhold, Ka Chun Yau, Carlos Echeverria, Beatriz Fontoura, Alexei Arnaoutov, Mary Dasso
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
mRNAs export from the nucleus is thought to be regulated in part by three nucleoporins that comprise the nuclear basket, but whether and how distinct basket nucleoporins interact with the RNA export machinery is unclear. Here, the authors use rapid a
Externí odkaz:
https://doaj.org/article/b11e933a22b94f5d92aa8aec90845e1b