Zobrazeno 1 - 10
of 64
pro vyhledávání: '"James I. Kim"'
Autor:
Yosuke Sato, Cierra N. Casson, Atsushi Matsuda, James I. Kim, Judy Qiuju Shi, Shinji Iwasaki, Susan Chen, Brett Modrell, Chingkit Chan, Daniel Tavares, Douglas Austen, Koh Ida, Olga Tayber, Pyae Hein, Robert Comeau, Yafang Lin, Michael H. Shaw
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2421-2431
Ipilimumab, a monoclonal antibody that recognizes cytotoxic T-lymphocyte associated protein 4 (CTLA-4), was the first immune checkpoint inhibitor approved by the FDA to treat metastatic melanoma patients. Multiple preclinical studies have proposed th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487812ab51e1103050ebdd7de9df9697
https://doi.org/10.1007/s00262-022-03170-z
https://doi.org/10.1007/s00262-022-03170-z
Autor:
Andrea Vergani, Francesca Gatti, Kang M. Lee, Francesca D'addio, Sara Tezza, Melissa Chin, Roberto Bassi, Ze Tian, Erxi Wu, Paola Maffi, Moufida Ben Nasr, James I. Kim, Antonio Secchi, James F. Markmann, David M. Rothstein, Laurence A. Turka, Mohamed H. Sayegh, Paolo Fiorina M.D., Ph.D
Publikováno v:
Cell Transplantation, Vol 24 (2015)
The role of the novel costimulatory molecule TIM4 in anti-islet response is unknown. We explored TIM4 expression and targeting in Th1 (BALB/c islets into C57BL/6 mice) and Th2 (BALB/c islets into Tbet -/- C57BL/6 mice) models of anti-islet alloimmune
Externí odkaz:
https://doaj.org/article/2190e16d63fc43438590df1120940b25
Autor:
Kang Mi Lee, Heidi Yeh, Gaoping Zhao, Lingling Wei, Matthew O'connor, Ryan T. Stott, Julie Soohoo, Kyri Dunussi, Paolo Fiorina, Shaoping Deng, James F. Markmann M.D., Ph.D., James I. Kim
Publikováno v:
Cell Transplantation, Vol 23 (2014)
A short course of anti-CD45RB leads to long-term islet allograft survival and donor-specific tolerance in approximately half of immunocompetent mice. We have previously demonstrated that anti-CD45RB antibody-mediated tolerance requires B-cells for ca
Externí odkaz:
https://doaj.org/article/b3b2b40e6e03443daf2ef544df212b1c
Autor:
James I Kim, Ryan T Stott, Julie Soohoo, Kang Mi Lee, Gaoping Zhao, Heidi Yeh, Shaoping Deng, James F Markmann
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82856 (2013)
Immunosenescence predisposes the elderly to infectious and autoimmune diseases and impairs the response to vaccination. We recently demonstrated that ageing also impedes development of transplantation tolerance. Unlike their young counterparts (8-12
Externí odkaz:
https://doaj.org/article/2a2ba3990216439d9681e1d8bda44949
Autor:
Daniel J. Moore, Andrew F. Marshall, Christian Schuetz, Maozhu Yang, James F. Markmann, James I. Kim, Shaoping Deng, Ji Lei, Matthew R O’Connor, Kang Mi Lee, Gaoping Zhao
Publikováno v:
Xenotransplantation. 21:567-573
For the sake of therapy of diabetes, it is critical to understand human beta cell function in detail in health and disease. Current studies of human beta cell physiology in vivo are mostly limited to immunodeficient mouse models, which possess signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882fe9e3b72c218bc1fa7a8166862b92
https://doi.org/10.1111/xen.12126
https://doi.org/10.1111/xen.12126
Autor:
Wei Xiong, R. Stott, James F. Markmann, Kang Mi Lee, Moh Moh Lian, Heidi Yeh, Gaoping Zhao, Elsie Akrawi, James I. Kim, Lindsey Fitzgerald, J. Soohoo, Ji Lei, S. Shi, Shaoping Deng
Publikováno v:
European Journal of Immunology. 44:1728-1736
Regulatory B (Breg) cells have been shown to play a critical role in immune homeostasis and in autoimmunity models. We have recently demonstrated that combined anti-T cell immunoglobulin domain and mucin domain-1 and anti-CD45RB antibody treatment re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e60123d90b903fca30245def5e78c4f8
https://doi.org/10.1002/eji.201344062
https://doi.org/10.1002/eji.201344062
Autor:
James F. Markmann, Gaoping Zhao, R. Stott, Matthew R O’Connor, Paolo Fiorina, Kyri Dunussi, Heidi Yeh, Kang Mi Lee, Lingling Wei, James I. Kim, Shaoping Deng, J. Soohoo
Publikováno v:
Cell Transplantation, Vol 23 (2014)
A short course of anti-CD45RB leads to long-term islet allograft survival and donor-specific tolerance in approximately half of immunocompetent mice. We have previously demonstrated that anti-CD45RB antibody-mediated tolerance requires B-cells for ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a723d44bea6a4d644db20a8010045c9e
https://doi.org/10.3727/096368912x658962
https://doi.org/10.3727/096368912x658962
Publikováno v:
Transplantation Reviews. 27:61-64
One of the most significant advances in the field of immunology in the last decade is delineation of the pivotal role of regulatory T cells (Tregs) in the maintenance of self-tolerance. While Tregs are just now being applied therapeutically in early
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6fe321a5ff53f0dd7235a46e9c911d
https://doi.org/10.1016/j.trre.2013.02.001
https://doi.org/10.1016/j.trre.2013.02.001
Publikováno v:
Frontiers in Immunology
B lymphocytes contribute to acute and chronic allograft rejection through their production of donor-specific antibodies (DSAs). In addition, B cells present allopeptides bound to self-MHC class II molecules and provide costimulation signals to T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291af776f641a0ff4b9bf846ca82474b
https://pubmed.ncbi.nlm.nih.gov/28210263
https://pubmed.ncbi.nlm.nih.gov/28210263
Autor:
Larry Steinman, Amit Bar-Or, Jacinta M. Behne, Daniel Benitez-Ribas, Peter S. Chin, Michael Clare-Salzler, Donald Healey, James I. Kim, David M. Kranz, Andreas Lutterotti, Roland Martin, Sven Schippling, Pablo Villoslada, Cheng-Hong Wei, Howard L. Weiner, Scott S. Zamvil, Michael R. Yeaman, Terry J. Smith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f404a745a55bbbedc9e805cd87a4860
