Zobrazeno 1 - 10
of 140
pro vyhledávání: '"James Hopkins"'
Autor:
Joshua Ames, Tejabhiram Yadavalli, Rahul Suryawanshi, James Hopkins, Alexander Agelidis, Chandrashekhar Patil, Brian Fredericks, Henry Tseng, Tibor Valyi-Nagy, Deepak Shukla
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
During herpesvirus infection, most individuals intrinsically suppress a primary infection and therewith preclude potential damage or neurodegeneration of the CNS. Here, Ames et al. show that Optineurin (OPTN), a conserved autophagy receptor, restrict
Externí odkaz:
https://doaj.org/article/04effd8ca26d4bee869ab8aa1646df51
Autor:
Ciara H. O’Flanagan, Kieran R. Campbell, Allen W. Zhang, Farhia Kabeer, Jamie L. P. Lim, Justina Biele, Peter Eirew, Daniel Lai, Andrew McPherson, Esther Kong, Cherie Bates, Kelly Borkowski, Matt Wiens, Brittany Hewitson, James Hopkins, Jenifer Pham, Nicholas Ceglia, Richard Moore, Andrew J. Mungall, Jessica N. McAlpine, The CRUK IMAXT Grand Challenge Team, Sohrab P. Shah, Samuel Aparicio
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Single-cell RNA sequencing (scRNA-seq) is a powerful tool for studying complex biological systems, such as tumor heterogeneity and tissue microenvironments. However, the sources of technical and biological variation in primary sol
Externí odkaz:
https://doaj.org/article/fa6f78c27ad142aba9a969b1f7cd721c
Autor:
Alex Agelidis, Benjamin A. Turturice, Rahul K. Suryawanshi, Tejabhiram Yadavalli, Dinesh Jaishankar, Joshua Ames, James Hopkins, Lulia Koujah, Chandrashekhar D. Patil, Satvik R. Hadigal, Evan J. Kyzar, Anaamika Campeau, Jacob M. Wozniak, David J. Gonzalez, Israel Vlodavsky, Jin-ping Li, David L. Perkins, Patricia W. Finn, Deepak Shukla
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
The drive to withstand environmental stresses and defend against invasion is a universal trait extant in all forms of life. While numerous canonical signaling cascades have been characterized in detail, it remains unclear how these pathways interface
Externí odkaz:
https://doaj.org/article/2ffdf956e9364785bc5fbcaa308dd5a9
Autor:
Emma Rose McGlone, Iain Carey, Vladica Veličković, Prem Chana, Kamal Mahawar, Rachel L Batterham, James Hopkins, Peter Walton, Robin Kinsman, James Byrne, Shaw Somers, David Kerrigan, Vinod Menon, Cynthia Borg, Ahmed Ahmed, Bruno Sgromo, Chandra Cheruvu, Gul Bano, Catherine Leonard, Howard Thom, Carel W le Roux, Marcus Reddy, Richard Welbourn, Peter Small, Omar A Khan
Publikováno v:
PLoS Medicine, Vol 17, Iss 12, p e1003228 (2020)
BackgroundAlthough bariatric surgery is well established as an effective treatment for patients with obesity and type 2 diabetes mellitus (T2DM), there exists reluctance to increase its availability for patients with severe T2DM. The aims of this stu
Externí odkaz:
https://doaj.org/article/d907c696d1794f7698c6183ece9164c6
Autor:
Nicole C. Woitowich, Andrei S. Halavaty, Patricia Waltz, Christopher Kupitz, Joseph Valera, Gregory Tracy, Kevin D. Gallagher, Elin Claesson, Takanori Nakane, Suraj Pandey, Garrett Nelson, Rie Tanaka, Eriko Nango, Eiichi Mizohata, Shigeki Owada, Kensure Tono, Yasumasa Joti, Angela C. Nugent, Hardik Patel, Ayesha Mapara, James Hopkins, Phu Duong, Dorina Bizhga, Svetlana E. Kovaleva, Rachael St. Peter, Cynthia N. Hernandez, Wesley B. Ozarowski, Shatabdi Roy-Chowdhuri, Jay-How Yang, Petra Edlund, Heikki Takala, Janne Ihalainen, Jennifer Brayshaw, Tyler Norwood, Ishwor Poudyal, Petra Fromme, John C. H. Spence, Keith Moffat, Sebastian Westenhoff, Marius Schmidt, Emina A. Stojković
Publikováno v:
IUCrJ, Vol 5, Iss 5, Pp 619-634 (2018)
Phytochromes are red-light photoreceptors that were first characterized in plants, with homologs in photosynthetic and non-photosynthetic bacteria known as bacteriophytochromes (BphPs). Upon absorption of light, BphPs interconvert between two states
Externí odkaz:
https://doaj.org/article/a56c4f1741084155bcfa230773aaee98
Autor:
Karen D Coulman, James Hopkins, Sara T Brookes, Katy Chalmers, Barry Main, Amanda Owen-Smith, Robert C Andrews, James Byrne, Jenny L Donovan, Graziella Mazza, Barnaby C Reeves, Chris A Rogers, Janice L Thompson, Richard Welbourn, Sarah Wordsworth, Jane M Blazeby, BARIACT working group
Publikováno v:
PLoS Medicine, Vol 13, Iss 11, p e1002187 (2016)
BackgroundBariatric and metabolic surgery is used as a treatment for patients with severe and complex obesity. However, there is a need to improve outcome selection and reporting in bariatric surgery trials. A Core Outcome Set (COS), an agreed minimu
Externí odkaz:
https://doaj.org/article/a0bf462dc32e440e9adbbc1ed5e17d04
Autor:
Simone T. Andersen, Beth S. Nelson, Katie A. Read, Shalini Punjabi, Luis Neves, Matthew J. Rowlinson, James Hopkins, Tomás Sherwen, Lisa K. Whalley, James D. Lee, Lucy J. Carpenter
Publikováno v:
Atmospheric Chemistry and Physics. 22:15747-15765
The photostationary state (PSS) equilibrium between NO and NO2 is reached within minutes in the atmosphere and can be described by the PSS parameter, φ. Deviations from expected values of φ have previously been used to infer missing oxidants in div
Autor:
Dominika Pasternak, James Lee, Beth Nelson, Magdalini Alexiadou, Loren Temple, Stéphane Bauguitte, Steph Batten, James Hopkins, Stephen Andrews, Emily Mathews, Thomas Bannan, Huihui Wu, Navaneeth Thamban, Nicholas Marsden, Ming-Xi Yang, Thomas Bell, Hugh Coe, Keith Bower
Since 1st January 2020 the legal sulphur content of shipping fuel was decreased – from 3.5% to 0.5% by mass outside of the Sulphur Emission Control Areas (SECAs) to improve coastal air quality. A possible downside of this change was acceleration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8158b85701bfd04ad5d5d1d712bc697c
https://doi.org/10.5194/egusphere-egu23-7986
https://doi.org/10.5194/egusphere-egu23-7986
Autor:
Roel Bolckmans, Alan Askari, Andrew Currie, Ahmed R. Ahmed, Rachel L. Batterham, James Byrne, James Hopkins, Omar A. Khan, Kamal Mahawar, Alexander Dimitri Miras, Chris M. Pring, Peter K. Small, Richard Welbourn
Publikováno v:
Clinical Obesity. 13
Baseline demographic characteristics and operations undertaken for patients having bariatric surgery in the United Kingdom are largely unknown. This study aimed to describe the profile of patients having primary bariatric surgery in the National Heal
Publikováno v:
Journal of Pediatric Surgery. 57:168-171
The inaugural certifying examination for special competence in pediatric surgery in North America was given by the American Board of Surgery (ABS) in April 1975, the day before the sixth meeting of the American Pediatric Surgical Association at a res