Zobrazeno 1 - 10
of 36
pro vyhledávání: '"James Heyward"'
Autor:
Rishav Adhikari, Kunal Jha, Zeina Dardari, James Heyward, Roger S. Blumenthal, Robert H. Eckel, G. Caleb Alexander, Michael J. Blaha
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 9 (2022)
Background Sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) mitigate cardiovascular risk in individuals with type 2 diabetes, but most eligible patients do not receive them. We cha
Externí odkaz:
https://doaj.org/article/54e819014e4549dc8a35d0dce0097b46
Publikováno v:
BMJ Open, Vol 10, Iss 6 (2020)
Objectives Little is routinely disclosed about the costs of the pivotal clinical trials that provide the key scientific evidence of the treatment benefits of new therapeutic agents. We expand our earlier research to examine why the estimated costs ma
Externí odkaz:
https://doaj.org/article/ee6ef03277a84a5a98be3b09c1f252a4
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234065 (2020)
BackgroundThe association between sodium-glucose cotransporter 2 inhibitors (SGLT2i's) and lower extremity amputation is unclear.PurposeTo systematically review randomized control trials (RCTs) and observational studies quantifying risk of lower extr
Externí odkaz:
https://doaj.org/article/cd85e32ccb90450989ebdbd3f3b69224
Autor:
Evan Mayo-Wilson, James Heyward, Anthony Keyes, Jesse Reynolds, Sarah White, Nidhi Atri, G. Caleb Alexander, Audrey Omar, Daniel E. Ford, on behalf of the National Clinical Trials Registration and Results Reporting Taskforce Survey Subcommittee
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Many clinical trials conducted by academic organizations are not published, or are not published completely. Following the US Food and Drug Administration Amendments Act of 2007, “The Final Rule” (compliance date April 18, 201
Externí odkaz:
https://doaj.org/article/bcb72671c9aa480aa84078d401041e37
Autor:
Evan Mayo-Wilson, Susan Hutfless, Tianjing Li, Gillian Gresham, Nicole Fusco, Jeffrey Ehmsen, James Heyward, Swaroop Vedula, Diana Lock, Jennifer Haythornthwaite, Jennifer L. Payne, Theresa Cowley, Elizabeth Tolbert, Lori Rosman, Claire Twose, Elizabeth A. Stuart, Hwanhee Hong, Peter Doshi, Catalina Suarez-Cuervo, Sonal Singh, Kay Dickersin
Publikováno v:
Systematic Reviews, Vol 7, Iss 1, Pp 1-1 (2018)
Abstract The correct title of the article [1] should be “Integrating multiple data sources (MUDS) for meta-analysis to improve patient-centered outcomes research: a protocol”.
Externí odkaz:
https://doaj.org/article/cd49912a530946bb8b26f6e4c6e7503a
Autor:
Jodi B. Segal, Ravi Varadhan, Rolf H.H. Groenwold, Nicholas C. Henderson, Xiaojuan Li, Kaori Nomura, Sigal Kaplan, Shirin Ardeshirrouhanifard, James Heyward, Fredrik Nyberg, Mehmet Burcu
Publikováno v:
Annals of Internal Medicine. 176:536-544
Autor:
Gene Pennello, Catherine Y. Spong, Milena Lolic, Ravi Varadhan, James Heyward, David C. Atkins
Publikováno v:
Pharmaceutical Statistics. 20:965-978
How do we communicate nuanced regulatory information to different audiences, recognizing that the consumer audience is very different from the physician audience? In particular, how do we communicate the heterogeneity of treatment effects - the poten
Autor:
Jennifer K. Chen, Thomas J. Moore, Kristin Meek, James Heyward, Peter Lurie, G. Caleb Alexander
Publikováno v:
Annals of Internal Medicine. 173:956-963
BACKGROUND Little is known about the evidence required by the U.S. Food and Drug Administration (FDA) for new approvals of opioid analgesics. OBJECTIVE To characterize the quality of safety and efficacy data in new drug applications (NDAs) for opioid
Publikováno v:
Annals of Internal Medicine
Publikováno v:
JAMA Network Open
Key Points Question What are the trends in ambulatory insulin use among adults with type 2 diabetes in the United States between 2016 and 2020? Findings In this cross-sectional study of 27.9 million ambulatory insulin treatment visits, the use of ins