Zobrazeno 1 - 10
of 28
pro vyhledávání: '"James H. Watterson"'
Publikováno v:
Journal of analytical toxicology. 43(9)
Ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC–QToF–MS) analysis of dextromethorphan (DXM) and its metabolites—dextrorphan, 3-methoxymorphinan (3-MEM) and 3-hydroxymorphinan—in skeletal remains of ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b2e2b65262eabbba0ae65c66c9e3eb
https://pubmed.ncbi.nlm.nih.gov/31504591
https://pubmed.ncbi.nlm.nih.gov/31504591
Autor:
James H. Watterson, K. A. Unger
Publikováno v:
Journal of Analytical Toxicology. 40:669-676
The effects of decomposition microclimate on the distribution of dextromethorphan (DXM) and dextrorphan (DXT) in skeletonized remains of rats acutely exposed to DXM were examined. Animals (n = 10) received DXM (75 mg/kg, i.p.), were euthanized 30 min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d5ed6c3b9a55e3a2adc9b39cb5dbf4
https://doi.org/10.1093/jat/bkw083
https://doi.org/10.1093/jat/bkw083
Publikováno v:
Drug testing and analysis. 10(6)
The use of filtration/pass-through extraction (FPTE) and ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-qTOF-MS) to detect tramadol (TRAM), dextromethorphan (DXM), and metabolites from skeletal remains is de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614402c2f69159e83fdf88f5bd59eb2e
https://pubmed.ncbi.nlm.nih.gov/29055108
https://pubmed.ncbi.nlm.nih.gov/29055108
Publikováno v:
Journal of analytical toxicology. 42(2)
Characterization of degradation products formed from selected phenothiazine drugs during standard solid-phase extraction (SPE) approaches is described. An analytical method for promethazine (PMZ), chlorpromazine (CPZ) and their respective N-desmethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde624708f45bb8f7b1a096fda617db8
https://pubmed.ncbi.nlm.nih.gov/29186521
https://pubmed.ncbi.nlm.nih.gov/29186521
Publikováno v:
Journal of analytical toxicology. 41(6)
Analysis of dextromethorphan (DXM) and its metabolite dextrorphan (DXT) in skeletal remains of rats following acute (ACU, 75 mg/kg, IP, n = 10) or three repeated (REP, 25 mg/kg, IP, n = 10, 40-min interval) doses of DXM is described. Following dosing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b6f2168231b4beccb2c376ba110a90
https://pubmed.ncbi.nlm.nih.gov/28830117
https://pubmed.ncbi.nlm.nih.gov/28830117
Publikováno v:
Journal of Analytical Toxicology. 38:548-554
The influence of body position and microclimate on ketamine (KET) and metabolite distribution in decomposed bone tissue was examined. Rats received 75 mg/kg (i.p.) KET (n = 30) or remained drug-free (controls, n = 4). Following euthanasia, rats were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae8e331828f8b212f82db312649807b
https://doi.org/10.1093/jat/bku053
https://doi.org/10.1093/jat/bku053
Autor:
Treena R. Wiebe, James H. Watterson
Publikováno v:
Forensic Science International. 242:261-265
Decomposed bone and plasma samples of rats exposed to tramadol (TRAM) under different dosing patterns were analyzed. Wistar rats received TRAM as one acute dose (n=4, 45 mg/kg, i.p.) or three doses (n=4, 15 mg/kg, i.p.), 40 min apart. Perimortem hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c05c9d1f06277d2be05d07e2a017857
https://doi.org/10.1016/j.forsciint.2014.07.010
https://doi.org/10.1016/j.forsciint.2014.07.010
Publikováno v:
Journal of Forensic Sciences. 57:544-549
Skeletal remains of a domestic pig were assessed for relative distribution of amitriptyline, citalopram, and metabolites. Following acute exposure and outdoor decomposition for 2 years, drugs and metabolites were analyzed in 13 different bones. Bones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3008ae5ac05db2f6357ee3957816fd3c
https://doi.org/10.1111/j.1556-4029.2011.01994.x
https://doi.org/10.1111/j.1556-4029.2011.01994.x
Publikováno v:
Drug Testing and Analysis. 2:346-356
Skeletal tissues have recently been investigated for use in post-mortem toxicology. Variables affecting drug concentration in these tissues, however, are still poorly characterized. In this work, the relative effects of burial on the response of enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3844713001dc16080c287d7bafb90ab0
https://doi.org/10.1002/dta.144
https://doi.org/10.1002/dta.144
Publikováno v:
Journal of Analytical Toxicology. 32:631-638
Ketamine exposure was detected in skeletal tissues by ELISA and liquid chromatography-tandem mass spectrometry (LC-MS-MS). Rats (n = 9) received ketamine hydrochloride acutely (75 mg/kg, i.p.) and were euthanized within 15, 30, or 90 min. Drug-free c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3208c2ee9f9c0b4d85b6df2381dbf5bc
https://doi.org/10.1093/jat/32.8.631
https://doi.org/10.1093/jat/32.8.631