Zobrazeno 1 - 10
of 19
pro vyhledávání: '"James H. Vickers"'
Autor:
Kuniaki Saito, Akio Noma, Mitsuru Seishima, Melvyn P. Heyes, James H. Vickers, Suwako Fujigaki, Hua Song, Satoshi Maeda
Publikováno v:
The Biochemical journal. 321
Apolipoproteins in cerebrospinal fluid (CSF) might have important functional roles in the pathophysiology of brain and lipid metabolism in the vascular component. The present study examined apolipoprotein A-I (apo-A-I) and apolipoprotein E (apo-E) le
Autor:
Markku Linnoila, D. M. Taub, James H. Vickers, Stephen J. Suomi, Patrick T. Mehlman, J. Dee Higley, Russell E. Poland
Publikováno v:
Biological psychiatry. 40(11)
We studied the potential roles of testosterone and serotonin in various forms of aggressive and violent behaviors by measuring each biochemical and behaviour in free-ranging adolescent male nonhuman primates. Our results showed that (1) CSF free test
Autor:
Stephen J. Suomi, Patrick T. Mehlman, I. Faucher, Markku Linnoila, James H. Vickers, D. M. Taub, James D. Higley, A. A. Lilly
Publikováno v:
The American journal of psychiatry. 151(10)
Objective: The purpose ofthis study was to examine the relationship between behavior and serotonin by using a nonhuman primate model of aggression and impulse control. Method: During a routine capture and medical examination, 26 adolescent male rhesu
Autor:
Charles Krieger, Melvyn P. Heyes, James H. Vickers, Bruce J. Brew, Kuniaki Saito, Naoki Sakai, Sheldon Milstien
Publikováno v:
Journal of neurochemistry. 63(3)
Nitric oxide has been proposed to mediate cytotoxic effects in inflammatory diseases. To investigate the possibility that overproduction of nitric oxide might play a role in the neuropathology of inflammatory and noninflammatory neurological diseases
Autor:
Kuniaki Saito, Sanford P. Markey, Melvyn P. Heyes, Sheldon Milstien, James H. Vickers, Eugene O. Major
Publikováno v:
Brain : a journal of neurology. 116
Quinolinic acid (QUIN), kynurenic acid (KYNA) and L-kynurenine (L-KYN) are neuroactive kynurenine pathway metabolites that accumulate in inflammatory neurological diseases. These increases were attributed to the induction of indoleamine-2,3-dioxygena
Autor:
Kuniaki Saito, James H. Vickers, Melvyn P. Heyes, David Jacobowitz, Osamu Takikawa, Sanford P. Markey
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 6(11)
Accumulation of the neurotoxin quinolinic acid within the brain occurs in a broad spectrum of patients with inflammatory neurologic disease and may be of neuropathologic significance. The production of quinolinic acid was postulated to reflect local
Autor:
James H. Vickers, Beth J Fernald, Sue B. Higley, Markku Linnoila, D. M. Taub, Stephen J. Suomi, Patrick T. Mehlman, J. Dee Higley, Stephen G. Lindell
Publikováno v:
Archives of General Psychiatry. 53:537
Background: The purpose of this study was to assess the impact of central serotonin turnover rate on survival to adulthood among nonhuman primates living in a large, free-ranging colony. Methods: The rate of mortality was ascertained over a 4-year pe
Autor:
D. M. Taub, Markku Linnoila, J. Dee Higley, Sue B. Higley, James H. Vickers, Stephen J. Suomi, Patrick T. Mehlman
Publikováno v:
Archives of General Psychiatry. 49:436
• Clinical and preclinical studies involving several different mammalian species and research paradigms suggest a negative correlation between aggression and central serotonin activity. To test the generalizability of laboratory findings in rhesus
Publikováno v:
Journal of Medical Primatology. 8:129-142
The Caribbean Primate Research Center recently contracted with the Food and Drug Administration to establish a free-ranging island breeding colony of rhesus monkeys. The goal of the program is to produce 600 to 800 offspring yearly from 1,000 breedin
Publikováno v:
JNCI: Journal of the National Cancer Institute. 54:1419-1426
Mice homozygous for the mutation "nude" (nu/nu) are athymic and lack thymus-dependent lymphocytes. Heterozygote (nu/+) controls, which are phenotypically and immunologically normal, and (nu/nu) mice were infected with 1.0 times 10-6 colony-forming un