Zobrazeno 1 - 5
of 5
pro vyhledávání: '"James H. Mazorodze"'
Autor:
Vikram Saini, Bridgette M. Cumming, Loni Guidry, Dirk A. Lamprecht, John H. Adamson, Vineel P. Reddy, Krishna C. Chinta, James H. Mazorodze, Joel N. Glasgow, Melissa Richard-Greenblatt, Anaximandro Gomez-Velasco, Horacio Bach, Yossef Av-Gay, Hyungjin Eoh, Kyu Rhee, Adrie J.C. Steyn
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 572-585 (2016)
The mechanisms by which Mycobacterium tuberculosis (Mtb) maintains metabolic equilibrium to survive during infection and upon exposure to antimycobacterial drugs are poorly characterized. Ergothioneine (EGT) and mycothiol (MSH) are the major redox bu
Externí odkaz:
https://doaj.org/article/e86030a4d9474eae8ff100fea63540c3
Autor:
Vikram Saini, Joel N. Glasgow, Jack R. Lancaster, Krishna C. Chinta, James H. Mazorodze, Darshan Reddy, Md. Aejazur Rahman, Adrie J. C. Steyn
Publikováno v:
Nitric Oxide. 59:28-41
Mycobacterium tuberculosis (Mtb) is a facultative intracellular pathogen and the second largest contributor to global mortality caused by an infectious agent after HIV. In infected host cells, Mtb is faced with a harsh intracellular environment inclu
Autor:
Loni Guidry, James H. Mazorodze, John H. Adamson, Kyu Y. Rhee, Bridgette M. Cumming, Joel N. Glasgow, Anaximandro Gómez-Velasco, Yossef Av-Gay, Hyungjin Eoh, Horacio Bach, Vineel P. Reddy, Vikram Saini, Krishna C. Chinta, Dirk A. Lamprecht, Melissa Richard-Greenblatt, Adrie J. C. Steyn
Publikováno v:
Cell Reports, Vol 14, Iss 3, Pp 572-585 (2016)
SummaryThe mechanisms by which Mycobacterium tuberculosis (Mtb) maintains metabolic equilibrium to survive during infection and upon exposure to antimycobacterial drugs are poorly characterized. Ergothioneine (EGT) and mycothiol (MSH) are the major r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d8aa09b7842d5b0bf559785589f2f8
https://europepmc.org/articles/PMC4732560/
https://europepmc.org/articles/PMC4732560/
Autor:
Dirk A. Lamprecht, Ryan M. Wells, Adrie J. C. Steyn, Vikram Saini, Bridgette M. Cumming, James H. Mazorodze
Publikováno v:
Molecular Genetics of Mycobacteria
During infection, Mycobacterium tuberculosis is exposed to a diverse array of microenvironments in the human host, each with its own unique set of redox conditions. Imbalances in the redox environment of the bacillus or the host environment serve as