Zobrazeno 1 - 10
of 25
pro vyhledávání: '"James H. Kimura"'
Autor:
Matthew B. Heller, Kornelia M. Szauter, Matthias K. Jansen, Michael Loomis, Katalin Csiszar, James H. Kimura, Tercia Ku, Richard A. Girton, Charles D. Boyd, Gordon Okimoto, Maarit Tiirikainen
Publikováno v:
Biochemistry Insights, Vol 2011, Iss 4, Pp 13-27 (2011)
Biochemistry Insights, Vol 4 (2011)
Biochemistry Insights, Vol 4 (2011)
In spite of current standard therapies to target the major pathomechanisms in myocardial infarction (MI), inflammatory gene expression patterns have been consistently revealed in MI patients. In a multiethnic cohort, we aimed to identify MI-associate
Autor:
Tamayuki Shinomura, Sayaka Nakamura, Magnus Höök, Shin Ichi Shirasawa, James H. Kimura, Kazuo Ito
Publikováno v:
Journal of Biological Chemistry. 283:33658-33664
Follicular dendritic cell-secreted protein (FDC-SP) is a small secretory protein having structural similarities to statherin, a protein in saliva thought to play a role in calcium retention in saliva. In contrast, FDC-SP is thought to play a role in
Publikováno v:
Biochemical and Biophysical Research Communications. 341:167-174
This study reports a new system that is very effective in identifying genes closely related to the early phase of chondrogenic differentiation. While studying chondrogenesis in a progenitor cell line, ATDC5, we found that the amount of culture media
Autor:
Takeshi Muneta, Masayuki Yoshimi, Magnus Höök, Tamayuki Shinomura, Hideaki Kamochi, Shin Ichi Shirasawa, James H. Kimura
Publikováno v:
Journal of Biochemistry. 137:79-85
We have developed a simple and unique strategy for identifying cell surface and extracellular matrix molecules produced by chondrocytes. Our strategy comprises two methods, retrovirus-based signal sequence gene trapping and culturing of Swarm rat cho
The establishment and characterization of an immortal cell line with a stable chondrocytic phenotype
Autor:
James H. Kimura, Karen B. King
Publikováno v:
Journal of Cellular Biochemistry. 89:992-1004
A cell line was developed from the transplantable Swarm rat chondrosarcoma (RCS) and has been maintained in continuous monolayer tissue culture for a number of years. This long term-cultured (LTC) cell line exhibits the morphological and biochemical
Autor:
Nancy Burton-Wurster, Scott Tashman, Dale R. Sumner, Rajesh V. Kamath, Wenhua Liu, James H. Kimura, George Lust, Tibor T. Glant, Gabriella Cs-Szabo
Publikováno v:
Journal of Orthopaedic Research. 21:730-737
The unilateral canine model is the most commonly used model of experimental osteoarthritis (OA). In this model, the anterior cruciate ligament (ACL) of one knee is transected and the contralateral joint is usually used as a control. However, dogs, si
Publikováno v:
The Anatomical Record. 267:292-295
During development and growth, biological tissues and organisms can control their size and mass by regulating cell number (Raff, 1992; Conlon and Raff, 1999). Later in life both cell number and organ mass decrease (Buetow, 1985). We demonstrate that
Publikováno v:
Annals of Biomedical Engineering. 29:476-482
As part of a program of research aimed at determining the role of mechanical forces in connective tissue differentiation, we have developed a model for investigating the effects of dynamic compressive loading on chondrocyte differentiation in vitro.
Autor:
J. I. Khoury, Mitchell B. Schaffler, David P. Fyhrie, James H. Kimura, Deepak Vashishth, Gary Gibson
Publikováno v:
Bone. 28:195-201
In this study, the influence of nonenzymatic glycation (NEG) on the mechanical properties of bone and bone collagen were investigated. Bovine cortical bone specimens were incubated in ribose to cause collagen cross-links in vitro, and nondestructive
Autor:
Yoshihiko Yamada, Takahiro Ochi, Kazuhiro Tanaka, James H. Kimura, Tomoatsu Kimura, Noriyuki Tsumaki
Publikováno v:
Journal of Biological Chemistry. 273:22861-22864
Type XI collagen, a heterotrimer specific to cartilage matrix, plays an important role in cartilage morphogenesis. We analyzed various alpha2(XI) collagen promoter-lacZ reporter gene constructs in transgenic mice to understand tissue-specific transcr